Bookmarks by ANSA NINAN https://padlet.com/ansaninan2002/Bookmarks Made with charm en-us 2022-05-09 07:36:14 UTC 2023-09-26 07:37:20 UTC hello@padlet.com Task 3: Gr 5-7Perform the first 7 steps from Task 2.8. Calculate the ratio of genotypes and phenotypes by dividing the number of squares with each outcome by the total number of squares.9. Discuss the results and interpret the patterns of inheritance observed in Punnett square. Determine the probability of offspring inheriting the dominant or recessive trait. ansaninan2002 https://padlet.com/ansaninan2002/Bookmarks/wish/2342016504 2022-10-16 17:20:10 UTC https://padlet.com/ansaninan2002/Bookmarks/wish/2342016504 UAE context: Research and find out some genetic disorders that are prevalent in UAE and follow Mendelian genetics like thalassemia, cystic fibrosis, Sickle Cell Anemia etc. ansaninan2002 https://padlet.com/ansaninan2002/Bookmarks/wish/2342018738 2022-10-16 17:23:45 UTC https://padlet.com/ansaninan2002/Bookmarks/wish/2342018738 Critical thinking/Challenge- illustrate one of the ways in which meiosis is responsible for the tremendous variation that exists in every sexual species. ansaninan2002 https://padlet.com/ansaninan2002/Bookmarks/wish/2342020870 2022-10-16 17:26:56 UTC https://padlet.com/ansaninan2002/Bookmarks/wish/2342020870 Plenary- Let’s go back to your hypothesis.  Do you think you had formulated the right hypothesis or do you want to change the hypothesis? After today’s lesson mention at least one importance of being aware of inheritance patterns of traits in the family. (BIG IDEA) Padlet- How well have you learnt monohybrid cross? ansaninan2002 https://padlet.com/ansaninan2002/Bookmarks/wish/2342030738 2022-10-16 17:42:13 UTC https://padlet.com/ansaninan2002/Bookmarks/wish/2342030738 Reflection, Process Success criteria , Plenary -???? ansaninan2002 https://padlet.com/ansaninan2002/Bookmarks/wish/2342050920 2022-10-16 18:13:16 UTC https://padlet.com/ansaninan2002/Bookmarks/wish/2342050920 ASSESSMENT -Blooket ansaninan2002 https://padlet.com/ansaninan2002/Bookmarks/wish/2342089554 2022-10-16 19:15:31 UTC https://padlet.com/ansaninan2002/Bookmarks/wish/2342089554 Innovation: Real life Case study 1: A brown-eyed man, whose mother was blue-eyed, marries a brown-eyed woman whose father had blue eyes. What is the probability that this couple will have a blue-eyed child? Find out using Punnett square. Analyze how meiosis leads to variations. ansaninan2002 https://padlet.com/ansaninan2002/Bookmarks/wish/2342467961 2022-10-17 03:30:12 UTC https://padlet.com/ansaninan2002/Bookmarks/wish/2342467961 Methodology-A monohybrid cross is the hybrid of two individuals with homozygous genotypes which result in the opposite phenotype for a certain genetic trait.” “The cross between two monohybrid traits (TT and tt) is called a Monohybrid Cross.” Monohybrid cross is responsible for the inheritance of one gene. ansaninan2002 https://padlet.com/ansaninan2002/Bookmarks/wish/2582407694 2023-05-08 17:08:41 UTC https://padlet.com/ansaninan2002/Bookmarks/wish/2582407694 Task-2 [Gr 3 and 4]-Determine the trait you want to study, such as eye color (dominant: brown(B), recessive: blue(b)).2. Assign one color of bean to represent the dominant allele (e.g., red bean-brown) and another color to represent the recessive allele (e.g., white bean- blue).3. Each group of 2 students will pick up 2 plastic bags filled with 4 red (brown) beans and 4 white (blue) beans. Create Punnett square. https://padlet.com/ansaninan2002/Bookmarks/wish/2586883223 2023-05-11 08:57:16 UTC https://padlet.com/ansaninan2002/Bookmarks/wish/2586883223 Starter-Quiz: Circle the choices that are examples of each of those words. 1. Dominant alleleD e k L N n R S 2. Recessive allele M n d F G r k P 3. Homozygous dominant AA Gg KK mm uu Rr TT. 4. Homozygous recessive Ff HH Oo qq Uu ww. 5. Genotypes in which dominant gene must show AA Dd EE ff Jj RR Ss 6. Genotypes in which recessive gene must show aa Gg Ff KK rr Oo Tt https://padlet.com/ansaninan2002/Bookmarks/wish/2586885184 2023-05-11 08:58:39 UTC https://padlet.com/ansaninan2002/Bookmarks/wish/2586885184 Task-1Group 1 and 2-Assign one color of bean to represent the dominant allele (e.g., red bean- brown) and another color to represent the recessive allele (e.g., white bean- blue).3. Each group of 2 students will pick up 1 plastic bag filled with 4 red (brown) beans and another one with 4 white (blue) beans. This represents the 2 parents. 4. If each bag represents the genotype of one parent. Write the resulting genotype and phenotype . Create punnett square d7539 https://padlet.com/ansaninan2002/Bookmarks/wish/2586904535 2023-05-11 09:13:54 UTC https://padlet.com/ansaninan2002/Bookmarks/wish/2586904535 SDG-COP28- Propose an environmental factor that might influence both phenotypic and genotypic traits in humans. https://padlet.com/ansaninan2002/Bookmarks/wish/2586912825 2023-05-11 09:21:25 UTC https://padlet.com/ansaninan2002/Bookmarks/wish/2586912825 Objective: Simulate a monohybrid cross and utilize the experimental data to develop a Punnett Square for the prediction of the offspring ansaninan2002 https://padlet.com/ansaninan2002/Bookmarks/wish/2717858329 2023-09-24 13:28:40 UTC https://padlet.com/ansaninan2002/Bookmarks/wish/2717858329 What new learning? ansaninan2002 https://padlet.com/ansaninan2002/Bookmarks/wish/2717987006 2023-09-24 16:00:22 UTC https://padlet.com/ansaninan2002/Bookmarks/wish/2717987006 Group 1 https://padlet.com/ansaninan2002/Bookmarks/wish/2720506639 2023-09-26 04:58:02 UTC https://padlet.com/ansaninan2002/Bookmarks/wish/2720506639 GROUP 4 https://padlet.com/ansaninan2002/Bookmarks/wish/2720524025 In the UAE, prevalent genetic disorders include thalassemia, a Mendelian blood disorder causing anemia, and cystic fibrosis, a genetic lung condition. Sickle cell anemia is less common but present among certain ethnic groups.






]]> 2023-09-26 05:10:46 UTC https://padlet.com/ansaninan2002/Bookmarks/wish/2720524025 GROUP - 3 https://padlet.com/ansaninan2002/Bookmarks/wish/2720684263 2023-09-26 07:12:20 UTC https://padlet.com/ansaninan2002/Bookmarks/wish/2720684263 Group 7 https://padlet.com/ansaninan2002/Bookmarks/wish/2720689064 2023-09-26 07:15:46 UTC https://padlet.com/ansaninan2002/Bookmarks/wish/2720689064 Group 7 - Punnett Square https://padlet.com/ansaninan2002/Bookmarks/wish/2720689814 2023-09-26 07:16:18 UTC https://padlet.com/ansaninan2002/Bookmarks/wish/2720689814 Group 3 i https://padlet.com/ansaninan2002/Bookmarks/wish/2720693126 2023-09-26 07:18:30 UTC https://padlet.com/ansaninan2002/Bookmarks/wish/2720693126 Group 5 https://padlet.com/ansaninan2002/Bookmarks/wish/2720694287 2023-09-26 07:19:20 UTC https://padlet.com/ansaninan2002/Bookmarks/wish/2720694287 Group 2 https://padlet.com/ansaninan2002/Bookmarks/wish/2720695255 2023-09-26 07:20:01 UTC https://padlet.com/ansaninan2002/Bookmarks/wish/2720695255 SDG-COP28 (group 3) https://padlet.com/ansaninan2002/Bookmarks/wish/2720698509 One environmental factor that might influence both phenotypic and genotypic traits in humans is exposure to certain pollutants or toxins. For example, exposure to air pollution or chemicals in the environment can potentially impact gene expression and lead to changes in phenotypic traits. This can manifest as respiratory issues, allergies, or even genetic mutations that can be passed down to future generations. It is important to study and mitigate the effects of such environmental factors to promote healthier outcomes for both current and future generations.]]> 2023-09-26 07:22:21 UTC https://padlet.com/ansaninan2002/Bookmarks/wish/2720698509 Group 1 10H (Punnett Square) https://padlet.com/ansaninan2002/Bookmarks/wish/2720698723 2023-09-26 07:22:30 UTC https://padlet.com/ansaninan2002/Bookmarks/wish/2720698723 Group 3 https://padlet.com/ansaninan2002/Bookmarks/wish/2720698927 2023-09-26 07:22:39 UTC https://padlet.com/ansaninan2002/Bookmarks/wish/2720698927 1 HGroup:CONTEXT UAE https://padlet.com/ansaninan2002/Bookmarks/wish/2720701146
  • Thalassemia: Thalassemia is a group of blood disorders characterized by the inadequate production of hemoglobin. It is relatively common in the UAE due to a high rate of consanguineous marriages.
  • Sickle Cell Anemia: Sickle Cell Anemia is another blood disorder where red blood cells become misshapen and break down. It's less common in the UAE compared to other regions, but still exists.
  • Cystic Fibrosis: Cystic Fibrosis is a genetic disorder affecting the respiratory, digestive, and reproductive systems. It occurs at lower frequencies in the UAE compared to other regions.
  • G6PD Deficiency: This is an X-linked recessive disorder that affects the red blood cells. It's relatively common in the UAE, particularly among males.
  • Phenylketonuria (PKU): PKU is a metabolic disorder that prevents the breakdown of phenylalanine. It's screened for in newborns and managed through dietary restrictions.
  • Alpha-Thalassemia: Another type of thalassemia, alpha-thalassemia, is also prevalent in the UAE.

    • ]]>     2023-09-26 07:24:10 UTC https://padlet.com/ansaninan2002/Bookmarks/wish/2720701146     Punnett square heterozygous https://padlet.com/ansaninan2002/Bookmarks/wish/2720701877 2023-09-26 07:24:44 UTC https://padlet.com/ansaninan2002/Bookmarks/wish/2720701877 GROUP 6 https://padlet.com/ansaninan2002/Bookmarks/wish/2720708600 2023-09-26 07:29:21 UTC https://padlet.com/ansaninan2002/Bookmarks/wish/2720708600 UAE genetic disorders https://padlet.com/ansaninan2002/Bookmarks/wish/2720709690 Cystic fibrosis is a genetic disorder that mainly affects the lungs, but can also affect the pancreas, liver, kidneys, and intestines. Common symptoms include:

    Difficulty breathing
    Frequent coughing
    Chest and sinus infections
    Production of sticky mucus
    Salty-tasting skin
    The Cystic Fibrosis Program at Cleveland Clinic Abu Dhabi specializes in the treatment of cystic fibrosis, a genetically-inherited disorder that mainly affects the lungs, but can also affect other organs.
    Thalassemia
    Thalassemia, a group of genetic (autosomal recessive) blood disorders characterised by abnormal hemoglobin production in red blood cells, is a major health challenge in the United Arab Emirates (UAE) burdening the healthcare system, individuals and families.
    It has been found that consanguineous marriages lead to the increased expression of autosomal recessive disorders
    Sickle blood cells 
    Sickle cell anemia also known as sickle cell disease is a genetic disorder of the red blood cells in which the body lacks enough healthy red blood cells to transport oxygen to the tissues and organs. In a normal situation, the red blood cells have a disc like shape which makes them flexible to travel through blood vessels. However, in sickle cell anemia, the red blood cells have an abnormal sickle or crescent like shape. This makes them rigid and sticky and prone to getting stuck in the small blood vessels which can block or slow down the blood flow hence disrupting oxygenation of the body tissues and organs. This can result in pain and organ damage.




    ]]>     2023-09-26 07:29:57 UTC https://padlet.com/ansaninan2002/Bookmarks/wish/2720709690     Innovation: Real Life Case Study 1 https://padlet.com/ansaninan2002/Bookmarks/wish/2720711562 2023-09-26 07:31:18 UTC https://padlet.com/ansaninan2002/Bookmarks/wish/2720711562 https://padlet.com/ansaninan2002/Bookmarks/wish/2720714901 Genetic variation is increased by meiosis because of recombination and independent assortment in meiosis, each gamete contains a different set of DNA. This produces a unique combination of genes in the resulting zygote.

    GROUP1]]>     2023-09-26 07:33:49 UTC https://padlet.com/ansaninan2002/Bookmarks/wish/2720714901     COP 28 group 1 10H https://padlet.com/ansaninan2002/Bookmarks/wish/2720715045 2023-09-26 07:33:56 UTC https://padlet.com/ansaninan2002/Bookmarks/wish/2720715045 Group 6 https://padlet.com/ansaninan2002/Bookmarks/wish/2720715210 The United Arab Emirates (UAE) has a relatively high prevalence of genetic disorders, like many other Arab countries . According to a recent study, the most common genetic disorders in the UAE are blood disorders such as:

    1.     Anemia

    2.     Sickle cell

    3.     Thalassemia

    4.     Haemophilia

    5.     Glucose-6-phosphate dehydrogenase deficiency (G6PD) 

    It’s worth noting that the UAE has a unique demographic, with close to 90% of the population being expatriate. A recent study analyzed all genetic disorders and gene variants reported in Emirati nationals and hosted on the Catalogue for Transmission Genetics in Arabs (CTGA), an open-access database hosting bibliographic data on human gene variants associated with inherited or heritable phenotypes in Arabs. To date, CTGA hosts 665 distinct genetic conditions that have been described in Emiratis, 621 of which follow a clear Mendelian inheritance. Over half of these are extremely rare according to global prevalence rates, predominantly with an autosomal recessive mode of inheritance. This is likely due to the relatively high consanguinity rates within the Emirati population. 


    ]]>     2023-09-26 07:34:03 UTC https://padlet.com/ansaninan2002/Bookmarks/wish/2720715210     New learning -Group 6 https://padlet.com/ansaninan2002/Bookmarks/wish/2720717426 We have gotten a better understanding of heterozygous crossing using a punnet square. ]]> 2023-09-26 07:35:37 UTC https://padlet.com/ansaninan2002/Bookmarks/wish/2720717426 Ayesha s and Apoorva https://padlet.com/ansaninan2002/Bookmarks/wish/2720717875 We learnt more about the seriousness of genetic disorders in UAE and how they are caused. We also learnt about homozygous and heterozygous alleles.]]> 2023-09-26 07:35:52 UTC https://padlet.com/ansaninan2002/Bookmarks/wish/2720717875 Group 3 https://padlet.com/ansaninan2002/Bookmarks/wish/2720718101 We’ve learned about the genotyping and phenotypic ratio and also more about homozygous and heterozygous alleles.]]> 2023-09-26 07:36:03 UTC https://padlet.com/ansaninan2002/Bookmarks/wish/2720718101 https://padlet.com/ansaninan2002/Bookmarks/wish/2720719138 2023-09-26 07:36:42 UTC https://padlet.com/ansaninan2002/Bookmarks/wish/2720719138