BIOL400921 Mol genetics by Ahmed, Mohammed https://padlet.com/mohammed_ahmed1/xm6cejsekuu49pha Made with a creative frenzy en-us 2021-10-05 17:26:11 UTC 2021-10-29 09:46:22 UTC hello@padlet.com Huntington's disease mohammed_ahmed1 https://padlet.com/mohammed_ahmed1/xm6cejsekuu49pha/wish/1793898807 2021-10-05 17:28:50 UTC https://padlet.com/mohammed_ahmed1/xm6cejsekuu49pha/wish/1793898807 hemochromatosis - Excess Iron in body mohammed_ahmed1 https://padlet.com/mohammed_ahmed1/xm6cejsekuu49pha/wish/1793912431 2021-10-05 17:33:14 UTC https://padlet.com/mohammed_ahmed1/xm6cejsekuu49pha/wish/1793912431 fragile X syndrome mohammed_ahmed1 https://padlet.com/mohammed_ahmed1/xm6cejsekuu49pha/wish/1793914591 2021-10-05 17:33:57 UTC https://padlet.com/mohammed_ahmed1/xm6cejsekuu49pha/wish/1793914591 Xeroderma pigmentosum mohammed_ahmed1 https://padlet.com/mohammed_ahmed1/xm6cejsekuu49pha/wish/1793917268 2021-10-05 17:34:50 UTC https://padlet.com/mohammed_ahmed1/xm6cejsekuu49pha/wish/1793917268 person is highly sensitive to sunlight, has premature skin ageing and is prone to developing skin cancers. mohammed_ahmed1 https://padlet.com/mohammed_ahmed1/xm6cejsekuu49pha/wish/1793922762 2021-10-05 17:36:38 UTC https://padlet.com/mohammed_ahmed1/xm6cejsekuu49pha/wish/1793922762 Point Mutation in DNA repair machinary mohammed_ahmed1 https://padlet.com/mohammed_ahmed1/xm6cejsekuu49pha/wish/1793927146 2021-10-05 17:38:06 UTC https://padlet.com/mohammed_ahmed1/xm6cejsekuu49pha/wish/1793927146 impaired nucleotide excision repair (NER) system mohammed_ahmed1 https://padlet.com/mohammed_ahmed1/xm6cejsekuu49pha/wish/1793927334 2021-10-05 17:38:10 UTC https://padlet.com/mohammed_ahmed1/xm6cejsekuu49pha/wish/1793927334 no cure for xeroderma pigmentosum. Gene therapy for xeroderma pigmentosum is a possible future avenue mohammed_ahmed1 https://padlet.com/mohammed_ahmed1/xm6cejsekuu49pha/wish/1793932793 2021-10-05 17:39:59 UTC https://padlet.com/mohammed_ahmed1/xm6cejsekuu49pha/wish/1793932793 https://padlet.com/mohammed_ahmed1/xm6cejsekuu49pha/wish/1853563279 HD is typically inherited from an affected parent, who carries a mutation in the huntingtin gene (HTT). However, up to 10% of cases are due to a new mutation.]]> 2021-10-29 09:25:23 UTC https://padlet.com/mohammed_ahmed1/xm6cejsekuu49pha/wish/1853563279 https://padlet.com/mohammed_ahmed1/xm6cejsekuu49pha/wish/1853563650 Trinucleotide repeat expansion ]]> 2021-10-29 09:25:40 UTC https://padlet.com/mohammed_ahmed1/xm6cejsekuu49pha/wish/1853563650 https://padlet.com/mohammed_ahmed1/xm6cejsekuu49pha/wish/1853564803 Expansion of CAG repeats of cytosine-adenine-guanine (known as a trinucleotide repeat expansion) in the gene coding for the huntingtin protein results in an abnormal mutant protein (mHtt), which gradually damages brain cells.]]> 2021-10-29 09:26:31 UTC https://padlet.com/mohammed_ahmed1/xm6cejsekuu49pha/wish/1853564803 caused due to multiple trinucleotide CAG repeats on the chr4 at loci 4p16.3 https://padlet.com/mohammed_ahmed1/xm6cejsekuu49pha/wish/1853565253 2021-10-29 09:26:51 UTC https://padlet.com/mohammed_ahmed1/xm6cejsekuu49pha/wish/1853565253 Mutation in the htt gene https://padlet.com/mohammed_ahmed1/xm6cejsekuu49pha/wish/1853565510 2021-10-29 09:27:01 UTC https://padlet.com/mohammed_ahmed1/xm6cejsekuu49pha/wish/1853565510 Fragile X syndrome caused by an abnormality (mutation) in the FMR1 gene. https://padlet.com/mohammed_ahmed1/xm6cejsekuu49pha/wish/1853565685 2021-10-29 09:27:10 UTC https://padlet.com/mohammed_ahmed1/xm6cejsekuu49pha/wish/1853565685 Huntington disease is an autosomal dominant mutation, having a change in one of the 2 copies in HTT gene that causes the condition https://padlet.com/mohammed_ahmed1/xm6cejsekuu49pha/wish/1853565979 2021-10-29 09:27:24 UTC https://padlet.com/mohammed_ahmed1/xm6cejsekuu49pha/wish/1853565979 https://padlet.com/mohammed_ahmed1/xm6cejsekuu49pha/wish/1853566190 •Depression
•Difficulty moving 
•Mood swings and personality changes
•Problems in swallowing, speaking and breathing.]]> 2021-10-29 09:27:33 UTC https://padlet.com/mohammed_ahmed1/xm6cejsekuu49pha/wish/1853566190 https://padlet.com/mohammed_ahmed1/xm6cejsekuu49pha/wish/1853566253 HTT mutation - CAG trinucleotide repeat JS]]> 2021-10-29 09:27:35 UTC https://padlet.com/mohammed_ahmed1/xm6cejsekuu49pha/wish/1853566253 https://padlet.com/mohammed_ahmed1/xm6cejsekuu49pha/wish/1853566634 Involuntary movements/chorea
Muscle dystonia
Impaired posture/balance
Difficulty with speech/swallowing]]> 2021-10-29 09:27:51 UTC https://padlet.com/mohammed_ahmed1/xm6cejsekuu49pha/wish/1853566634 https://padlet.com/mohammed_ahmed1/xm6cejsekuu49pha/wish/1853566705 Hemochromatosis - type 1 substitution mutation in HFE gene, type 2 in HJV/HAMP, type 3 in TFR2 gene, and type 4 in SLC40A1 gene]]> 2021-10-29 09:27:55 UTC https://padlet.com/mohammed_ahmed1/xm6cejsekuu49pha/wish/1853566705 elzadayathomas18m https://padlet.com/mohammed_ahmed1/xm6cejsekuu49pha/wish/1853567521 Inherited from affected parents]]> 2021-10-29 09:28:33 UTC https://padlet.com/mohammed_ahmed1/xm6cejsekuu49pha/wish/1853567521 https://padlet.com/mohammed_ahmed1/xm6cejsekuu49pha/wish/1853567720 No cure for HD is known, and full-time care is required in the later stages. Treatments can relieve some symptoms, and in some, improve quality of life.]]> 2021-10-29 09:28:43 UTC https://padlet.com/mohammed_ahmed1/xm6cejsekuu49pha/wish/1853567720 Fragile X https://padlet.com/mohammed_ahmed1/xm6cejsekuu49pha/wish/1853567809 Caused by A methylation to the FMR1 gene which causes the resulting FMRP protein to be deficient.]]> 2021-10-29 09:28:47 UTC https://padlet.com/mohammed_ahmed1/xm6cejsekuu49pha/wish/1853567809 HD symptoms- difficulty concentrating and memory lapses, Depression, stumbling and clumsiness, mood swings and personality changes, involuntary jerking, problems swallowing, speaking and breathing, difficulty moving https://padlet.com/mohammed_ahmed1/xm6cejsekuu49pha/wish/1853568217 2021-10-29 09:29:05 UTC https://padlet.com/mohammed_ahmed1/xm6cejsekuu49pha/wish/1853568217 https://padlet.com/mohammed_ahmed1/xm6cejsekuu49pha/wish/1853568613 Uncontrollable body movements called chorea
rigidity
writhing motions
abnormal posturing]]> 2021-10-29 09:29:20 UTC https://padlet.com/mohammed_ahmed1/xm6cejsekuu49pha/wish/1853568613 mutation in the HTT gene via Repeat expansion. https://padlet.com/mohammed_ahmed1/xm6cejsekuu49pha/wish/1853568996 2021-10-29 09:29:38 UTC https://padlet.com/mohammed_ahmed1/xm6cejsekuu49pha/wish/1853568996 https://padlet.com/mohammed_ahmed1/xm6cejsekuu49pha/wish/1853569447 Hemochromatosis - Joint pain, abdominal pain, weight loss, chronic fatigue, impotence, jaundice, arrhythmia, alopecia.]]> 2021-10-29 09:30:00 UTC https://padlet.com/mohammed_ahmed1/xm6cejsekuu49pha/wish/1853569447 HD https://padlet.com/mohammed_ahmed1/xm6cejsekuu49pha/wish/1853569452 Mostly caused by a mutation in the HTT gene - involving a DNA segment known as CAG trinucleotide repeat.]]> 2021-10-29 09:30:00 UTC https://padlet.com/mohammed_ahmed1/xm6cejsekuu49pha/wish/1853569452 https://padlet.com/mohammed_ahmed1/xm6cejsekuu49pha/wish/1853569494 There is no cure for Huntington's disease]]> 2021-10-29 09:30:01 UTC https://padlet.com/mohammed_ahmed1/xm6cejsekuu49pha/wish/1853569494 Inability to concentrate https://padlet.com/mohammed_ahmed1/xm6cejsekuu49pha/wish/1853569991 Clumsiness
Loss of short term memory
Mood swings
Depression
Aggressive behaviour
Difficulty in speech and swallowing

]]> 2021-10-29 09:30:26 UTC https://padlet.com/mohammed_ahmed1/xm6cejsekuu49pha/wish/1853569991 symptoms https://padlet.com/mohammed_ahmed1/xm6cejsekuu49pha/wish/1853570947 depression
poor coordination
irritability   ]]> 2021-10-29 09:31:08 UTC https://padlet.com/mohammed_ahmed1/xm6cejsekuu49pha/wish/1853570947 https://padlet.com/mohammed_ahmed1/xm6cejsekuu49pha/wish/1853571046 Involuntary movements
Depression
Stumbling and difficulty moving
Personality alterations and mood swings]]> 2021-10-29 09:31:13 UTC https://padlet.com/mohammed_ahmed1/xm6cejsekuu49pha/wish/1853571046 https://padlet.com/mohammed_ahmed1/xm6cejsekuu49pha/wish/1853571186 Trinucleotide CAG repeats numbering over 28 are unstable during replication, and this instability increases with the number of repeats present.]]> 2021-10-29 09:31:20 UTC https://padlet.com/mohammed_ahmed1/xm6cejsekuu49pha/wish/1853571186 Fragile X syndrome (ADSPS) https://padlet.com/mohammed_ahmed1/xm6cejsekuu49pha/wish/1853571519 Person has trouble learning skills like walking, sitting, etc.
Extreme sensitivity to light or sound.
Anxiety.
Hyperactivity.]]> 2021-10-29 09:31:33 UTC https://padlet.com/mohammed_ahmed1/xm6cejsekuu49pha/wish/1853571519 Fragile X syndrome has no actual cure however, educational, behaviour and physical therapy and medicines can be opted for treatment. https://padlet.com/mohammed_ahmed1/xm6cejsekuu49pha/wish/1853571731 2021-10-29 09:31:43 UTC https://padlet.com/mohammed_ahmed1/xm6cejsekuu49pha/wish/1853571731 Motor and cognitive disfunction , psychiatric symptoms, physical symptoms like tremor , chorea https://padlet.com/mohammed_ahmed1/xm6cejsekuu49pha/wish/1853572020 2021-10-29 09:31:56 UTC https://padlet.com/mohammed_ahmed1/xm6cejsekuu49pha/wish/1853572020 https://padlet.com/mohammed_ahmed1/xm6cejsekuu49pha/wish/1853572228 base excision repair mechanism]]> 2021-10-29 09:32:04 UTC https://padlet.com/mohammed_ahmed1/xm6cejsekuu49pha/wish/1853572228 HD https://padlet.com/mohammed_ahmed1/xm6cejsekuu49pha/wish/1853572542 Difficulty concentrating and memory lapses, depression, stumbling and clumsiness, moody swings and personality changes , involuntary jerking, fidgety movements of the limbs and body, problems swallowing]]> 2021-10-29 09:32:19 UTC https://padlet.com/mohammed_ahmed1/xm6cejsekuu49pha/wish/1853572542 HD occurs as a result of an alteration in HTT gene. and the result mutagene is passed from one generation to another. https://padlet.com/mohammed_ahmed1/xm6cejsekuu49pha/wish/1853572711 2021-10-29 09:32:27 UTC https://padlet.com/mohammed_ahmed1/xm6cejsekuu49pha/wish/1853572711 https://padlet.com/mohammed_ahmed1/xm6cejsekuu49pha/wish/1853572728 DNA mismatch repair]]> 2021-10-29 09:32:28 UTC https://padlet.com/mohammed_ahmed1/xm6cejsekuu49pha/wish/1853572728 elzadayathomas18m https://padlet.com/mohammed_ahmed1/xm6cejsekuu49pha/wish/1853572843 Difficulty to concentrate,
Problems in swallowing, speaking and breathing. Stumbling and clumsiness]]> 2021-10-29 09:32:33 UTC https://padlet.com/mohammed_ahmed1/xm6cejsekuu49pha/wish/1853572843 https://padlet.com/mohammed_ahmed1/xm6cejsekuu49pha/wish/1853572943 C282Y and H63D mutations in HFE gene]]> 2021-10-29 09:32:37 UTC https://padlet.com/mohammed_ahmed1/xm6cejsekuu49pha/wish/1853572943 XP parisatorbati https://padlet.com/mohammed_ahmed1/xm6cejsekuu49pha/wish/1853573407 -severe sunburn
- freckling
- dry skin
- nervous system problems (e.g. hearing loss, seizure, etc.)
- cataracts

]]> 2021-10-29 09:32:56 UTC https://padlet.com/mohammed_ahmed1/xm6cejsekuu49pha/wish/1853573407 https://padlet.com/mohammed_ahmed1/xm6cejsekuu49pha/wish/1853574225 Weight loss, weakness, fatigue]]> 2021-10-29 09:33:31 UTC https://padlet.com/mohammed_ahmed1/xm6cejsekuu49pha/wish/1853574225 https://padlet.com/mohammed_ahmed1/xm6cejsekuu49pha/wish/1853574732 An increase in the reaction of ROS to damage the HTT gene.]]> 2021-10-29 09:33:56 UTC https://padlet.com/mohammed_ahmed1/xm6cejsekuu49pha/wish/1853574732 https://padlet.com/mohammed_ahmed1/xm6cejsekuu49pha/wish/1853574739 mutation in HFE on the short arm of chr 6]]> 2021-10-29 09:33:56 UTC https://padlet.com/mohammed_ahmed1/xm6cejsekuu49pha/wish/1853574739 HD https://padlet.com/mohammed_ahmed1/xm6cejsekuu49pha/wish/1853574768 No cure, however there are medications to keep the symptoms under control such as tetrabenazine, antipsychotic drugs, antidepressants and tranquillisers]]> 2021-10-29 09:33:58 UTC https://padlet.com/mohammed_ahmed1/xm6cejsekuu49pha/wish/1853574768 https://padlet.com/mohammed_ahmed1/xm6cejsekuu49pha/wish/1853575223 Hemochromatosis - No cure, but gene therapy is available. Therapy aims to reduce DMT-1 transporter gene expression, inhibiting iron uptake in the gut. ]]> 2021-10-29 09:34:22 UTC https://padlet.com/mohammed_ahmed1/xm6cejsekuu49pha/wish/1853575223 In Fragile x male child has behavioral problem, developmental problem with walking... https://padlet.com/mohammed_ahmed1/xm6cejsekuu49pha/wish/1853575575 2021-10-29 09:34:38 UTC https://padlet.com/mohammed_ahmed1/xm6cejsekuu49pha/wish/1853575575 Mutation inthe FMR1gene causes Fragile X syndrome https://padlet.com/mohammed_ahmed1/xm6cejsekuu49pha/wish/1853575726 2021-10-29 09:34:45 UTC https://padlet.com/mohammed_ahmed1/xm6cejsekuu49pha/wish/1853575726 https://padlet.com/mohammed_ahmed1/xm6cejsekuu49pha/wish/1853575796 Huntingtin repair complex is impaired and which usually excises products of oxidative DNA damage. Expanded huntingtin accumulates adducts and cannot excise N6FFA]]> 2021-10-29 09:34:50 UTC https://padlet.com/mohammed_ahmed1/xm6cejsekuu49pha/wish/1853575796 https://padlet.com/mohammed_ahmed1/xm6cejsekuu49pha/wish/1853576257 damaging the ubiquitin-protease system]]> 2021-10-29 09:35:10 UTC https://padlet.com/mohammed_ahmed1/xm6cejsekuu49pha/wish/1853576257 XP parisatorbati https://padlet.com/mohammed_ahmed1/xm6cejsekuu49pha/wish/1853576285 no certain treatment. only preventing symptoms via avoiding UV]]> 2021-10-29 09:35:11 UTC https://padlet.com/mohammed_ahmed1/xm6cejsekuu49pha/wish/1853576285 Cystic fibrosis https://padlet.com/mohammed_ahmed1/xm6cejsekuu49pha/wish/1853576356 2021-10-29 09:35:15 UTC https://padlet.com/mohammed_ahmed1/xm6cejsekuu49pha/wish/1853576356 treatment https://padlet.com/mohammed_ahmed1/xm6cejsekuu49pha/wish/1853576390 no cure currently, care and support can help reduce the problems caused by the condition. ]]> 2021-10-29 09:35:16 UTC https://padlet.com/mohammed_ahmed1/xm6cejsekuu49pha/wish/1853576390 Fragile X syndrome stuttering, developmental delays, intellectual and learning disabilities* general or social anxiety* autism* impulsiveness https://padlet.com/mohammed_ahmed1/xm6cejsekuu49pha/wish/1853576593 2021-10-29 09:35:27 UTC https://padlet.com/mohammed_ahmed1/xm6cejsekuu49pha/wish/1853576593 Hemochromatosis https://padlet.com/mohammed_ahmed1/xm6cejsekuu49pha/wish/1853577317 Phlebotomy]]> 2021-10-29 09:36:02 UTC https://padlet.com/mohammed_ahmed1/xm6cejsekuu49pha/wish/1853577317 FXS is caused by a defect in the FMR1 gene located on the X chromosome. https://padlet.com/mohammed_ahmed1/xm6cejsekuu49pha/wish/1853577595 2021-10-29 09:36:15 UTC https://padlet.com/mohammed_ahmed1/xm6cejsekuu49pha/wish/1853577595 Fragile x syndrome https://padlet.com/mohammed_ahmed1/xm6cejsekuu49pha/wish/1853577924 Is a genetic condition that causes a range of developmental problems, especially learning disabilities and cognitive impairment. ]]> 2021-10-29 09:36:32 UTC https://padlet.com/mohammed_ahmed1/xm6cejsekuu49pha/wish/1853577924 CF- germline mutation, faulty gene that affects the movement salt and water in and out of the cells https://padlet.com/mohammed_ahmed1/xm6cejsekuu49pha/wish/1853578570 2021-10-29 09:36:57 UTC https://padlet.com/mohammed_ahmed1/xm6cejsekuu49pha/wish/1853578570 Hemochromatosis https://padlet.com/mohammed_ahmed1/xm6cejsekuu49pha/wish/1853579262 •Joint pain
•Weekness
•Weight loss

]]> 2021-10-29 09:37:29 UTC https://padlet.com/mohammed_ahmed1/xm6cejsekuu49pha/wish/1853579262 Fragile X syndrome - ADSPS https://padlet.com/mohammed_ahmed1/xm6cejsekuu49pha/wish/1853579386 Base Excision Repair 
DNA mismatch repair
Down regulation of DNA damage pathway transcripts.]]> 2021-10-29 09:37:36 UTC https://padlet.com/mohammed_ahmed1/xm6cejsekuu49pha/wish/1853579386 https://padlet.com/mohammed_ahmed1/xm6cejsekuu49pha/wish/1853580038
Mismatch Repair
Somatic CAG Expansion
NER
Base excision repair uses enzymes like DNA Polymerase β, Flap endonuclease 1 and DNA ligase in preventing strand slippage and trinucleotide-repeat expansion]]> 2021-10-29 09:38:08 UTC https://padlet.com/mohammed_ahmed1/xm6cejsekuu49pha/wish/1853580038 CF- chest infection, difficulty putting on weight, malnutrition, Jaundice, diarrhea, constipation https://padlet.com/mohammed_ahmed1/xm6cejsekuu49pha/wish/1853580103 2021-10-29 09:38:12 UTC https://padlet.com/mohammed_ahmed1/xm6cejsekuu49pha/wish/1853580103 DNA methylation leads to DNA repair down regulation and trinucleotide instability in mitotically activated Huntington disease cells https://padlet.com/mohammed_ahmed1/xm6cejsekuu49pha/wish/1853580118 2021-10-29 09:38:13 UTC https://padlet.com/mohammed_ahmed1/xm6cejsekuu49pha/wish/1853580118 HD https://padlet.com/mohammed_ahmed1/xm6cejsekuu49pha/wish/1853580814 Base excision repair, nucleotide excision repair]]> 2021-10-29 09:38:48 UTC https://padlet.com/mohammed_ahmed1/xm6cejsekuu49pha/wish/1853580814 CF- treatment can help with symptoms but no cure yet https://padlet.com/mohammed_ahmed1/xm6cejsekuu49pha/wish/1853581326 2021-10-29 09:39:14 UTC https://padlet.com/mohammed_ahmed1/xm6cejsekuu49pha/wish/1853581326 Fragile X syndrome https://padlet.com/mohammed_ahmed1/xm6cejsekuu49pha/wish/1853581491 Anxiety 
Extreme sensitivity to light or sound
Difficulty in learning skills like walking, sitting ]]> 2021-10-29 09:39:21 UTC https://padlet.com/mohammed_ahmed1/xm6cejsekuu49pha/wish/1853581491 https://padlet.com/mohammed_ahmed1/xm6cejsekuu49pha/wish/1853581714
  • Normal: Individuals with less than 45 CGG repeats have a normal FMR1 gene.
  • Intermediate: Those with 45-54 CGG repeats have what is called an “intermediate” or “gray zone allele,” which does not cause any of the known Fragile X associated disorders.
  • Premutation: Individuals with 55-200 CGG repeats have a premutation, which means they carry an unstable mutation of the gene that can expand in future generations and thus cause Fragile X syndrome in their children or grandchildren. Individuals with a premutation can also develop FXTAS or FXPOI themselves.
  • Full Mutation: Individuals with over 200 CGG repeats have a full mutation of the FMR1 gene, which causes Fragile X syndrome.

    • ]]>     2021-10-29 09:39:32 UTC https://padlet.com/mohammed_ahmed1/xm6cejsekuu49pha/wish/1853581714     Early symptoms include irritability, depreesion, memory lapses, mood swings https://padlet.com/mohammed_ahmed1/xm6cejsekuu49pha/wish/1853581914 2021-10-29 09:39:42 UTC https://padlet.com/mohammed_ahmed1/xm6cejsekuu49pha/wish/1853581914 There is no cure for Huntington disease, tetrabenazine was used to treat the disease like chorea https://padlet.com/mohammed_ahmed1/xm6cejsekuu49pha/wish/1853582438 2021-10-29 09:40:09 UTC https://padlet.com/mohammed_ahmed1/xm6cejsekuu49pha/wish/1853582438 Hyperactive, Anxiety, difficulty focusing on specific thing. https://padlet.com/mohammed_ahmed1/xm6cejsekuu49pha/wish/1853582439 2021-10-29 09:40:09 UTC https://padlet.com/mohammed_ahmed1/xm6cejsekuu49pha/wish/1853582439 https://padlet.com/mohammed_ahmed1/xm6cejsekuu49pha/wish/1853583019 Hemochromatosis symptoms include:
    • Joint pain.
    • Abdominal pain.
    • Fatigue.
    • Weakness.
    • Diabetes.
    • Impotence.
    • Heart failure.

    ]]>     2021-10-29 09:40:38 UTC https://padlet.com/mohammed_ahmed1/xm6cejsekuu49pha/wish/1853583019     Hemochromatosis https://padlet.com/mohammed_ahmed1/xm6cejsekuu49pha/wish/1853583211 The mutation occurs in HFE gene on the short arm of chromosome 6]]> 2021-10-29 09:40:47 UTC https://padlet.com/mohammed_ahmed1/xm6cejsekuu49pha/wish/1853583211 Mutation at FMR1 gene https://padlet.com/mohammed_ahmed1/xm6cejsekuu49pha/wish/1853584209 2021-10-29 09:41:39 UTC https://padlet.com/mohammed_ahmed1/xm6cejsekuu49pha/wish/1853584209 https://padlet.com/mohammed_ahmed1/xm6cejsekuu49pha/wish/1853585182 Haemochromatosis treatments that can reduce the amount of iron in your body such as Phlebotomy and Chelation therapy.


    ]]>     2021-10-29 09:42:27 UTC https://padlet.com/mohammed_ahmed1/xm6cejsekuu49pha/wish/1853585182     https://padlet.com/mohammed_ahmed1/xm6cejsekuu49pha/wish/1853589625 Hemochromatosis involves point mutation in the HFE gene on the short arm of chromosome 6. Most patients have a substitution of tyrosine for cysteine at position 282 (C282Y).]]> 2021-10-29 09:46:06 UTC https://padlet.com/mohammed_ahmed1/xm6cejsekuu49pha/wish/1853589625 CF- gene edting, however, method is challenging and low success rate https://padlet.com/mohammed_ahmed1/xm6cejsekuu49pha/wish/1853589916 2021-10-29 09:46:22 UTC https://padlet.com/mohammed_ahmed1/xm6cejsekuu49pha/wish/1853589916