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      <title>CBL- GASTRIC CARCINOMA: Students to post answers for the questions in description.The groups should make minimum two posts, you can comment on others posts and question others posts also.Scope: Clinical Reasoning &amp; Diagnosis
Tasks (short keyword-based Padlet posts):
1.	What is the significance of mass in pyloric region?
2.	What is the eponym of supraclavicular lymphadenopathy ? List some other eponyms used in clinical practice regarding carcinoma stomach. by Dharma Saranya</title>
      <link>https://padlet.com/dharmasaranya3/xkgynid5rr8ap14z</link>
      <description>A 58-year-old male from a rural background presents with fatigue, epigastric discomfort, weight loss, early satiety, and dark-colored stools. He has a history of chronic gastritis and heavy smoking. On examination, he is pale with a hard, palpable epigastric mass and left supraclavicular lymphadenopathy. Endoscopy shows an ulcerated mass in the pyloric region; biopsy reveals poorly differentiated adenocarcinoma. HER2 testing is positive.</description>
      <language>en-us</language>
      <pubDate>2025-06-07 14:26:31 UTC</pubDate>
      <lastBuildDate>2025-06-16 10:08:27 UTC</lastBuildDate>
      <webMaster>hello@padlet.com</webMaster>
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         <title>1. Significance of growth in pyloric region - could cause gastric outlet obstruction... Causes include - cicatrisation of duodenal ulcer, carcinoma of stomach.</title>
         <author></author>
         <link>https://padlet.com/dharmasaranya3/xkgynid5rr8ap14z/wish/3482057750</link>
         <description><![CDATA[<p>2. Troisiers sign, Sister Mary Joseph nodules, Irish nodes</p>]]></description>
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         <pubDate>2025-06-07 15:18:53 UTC</pubDate>
         <guid>https://padlet.com/dharmasaranya3/xkgynid5rr8ap14z/wish/3482057750</guid>
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         <title></title>
         <author></author>
         <link>https://padlet.com/dharmasaranya3/xkgynid5rr8ap14z/wish/3482058080</link>
         <description><![CDATA[<p>Mass in pyloric region can be benign or malignant. <strong>BENIGN</strong> mass may be leiomyoma which is rare.<strong>CIACATRISATION</strong> of pyloric ulcer can mimic like a mass which leads to pyloric <a rel="noopener noreferrer nofollow" href="http://stenosis.It">stenosis.It</a> may be malignant like <strong>GASTRIC CARCINOMA,GASRIC LYMPHOMA.</strong>Any mass whether it is benign or malignant ,if it totally occludes the pylorus,food cannot <a rel="noopener noreferrer nofollow" href="http://pass.so">pass.so</a> symptoms like  projectile vomiting of undigested food,loss of weight,loss of appetite,continuous vomiting leads to dehydration,abdominal pain,mass per abdomen,anemia.</p><p><br></p><ol start="2"><li><p><strong>Eponym of left supraclavicular lymphadenopathy</strong>-Troisier sign</p></li><li><p><strong>Irish node</strong>-left axillary lymphadenopathy</p></li><li><p><strong>Sister Mary Joseph nodule</strong> -nodule around umbilicus</p></li><li><p><strong>Blumer shelf</strong>-rectal deposits of carcinoma</p></li><li><p><strong>Krukenberg tumor</strong>-transperitoneal spread of carcinoma to ovary through paraaortic lymph node</p></li><li><p><br></p></li></ol><p><br></p><p><br></p>]]></description>
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         <pubDate>2025-06-07 15:19:54 UTC</pubDate>
         <guid>https://padlet.com/dharmasaranya3/xkgynid5rr8ap14z/wish/3482058080</guid>
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         <title></title>
         <author></author>
         <link>https://padlet.com/dharmasaranya3/xkgynid5rr8ap14z/wish/3482059034</link>
         <description><![CDATA[<p>1. What is the significance of mass in pyloric region?</p><p>The significance of a mass in the pyloric region, especially in the context of the clinical scenario described (58-year-old male with fatigue, epigastric discomfort, weight loss, early satiety, dark colored stools, history of chronic gastritis, and heavy smoking, along with a palpable epigastric mass and left supraclavicular lymphadenopathy), is highly suggestive of gastric carcinoma (stomach cancer).</p><p>The pyloric region is a common site for gastric tumors. A mass in this area can indicate the primary tumor itself. The symptoms like weight loss, early satiety, and dark stools (melena, indicating upper GI bleeding) are classic signs of advanced gastric cancer.</p><p>2. What is the eponym of supraclavicular lymphadenopathy? List some other eponyms used in clinical practice regarding carcinoma stomach.</p><p> * Eponym of supraclavicular lymphadenopathy: The eponym for left supraclavicular lymphadenopathy, particularly in the context of gastric or other abdominal malignancies, is Virchow's node (also known as Troisier's sign). It indicates metastatic spread to the lymphatic system.</p><p> * Other eponyms used in clinical practice regarding carcinoma stomach:</p><p>   * Krukenberg tumor: Refers to metastatic adenocarcinoma in the ovary, typically originating from the gastrointestinal tract, most commonly the stomach.</p><p>   * Sister Mary Joseph nodule: A metastatic tumor in the umbilicus, often originating from gastric, ovarian, or pancreatic cancer.</p><p>   * Blumer's shelf: A palpable shelf-like lesion in the rectum, indicating metastatic deposits from abdominal malignancies, including gastric cancer, that have spread to the rectovesical or rectouterine pouch.</p><p>   * Irish node: An enlarged anterior axillary lymph node, which can be a metastatic site from gastric carcinoma (less common than Vircho</p><p>w's node).</p>]]></description>
         <enclosure url="" />
         <pubDate>2025-06-07 15:23:03 UTC</pubDate>
         <guid>https://padlet.com/dharmasaranya3/xkgynid5rr8ap14z/wish/3482059034</guid>
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         <title></title>
         <author></author>
         <link>https://padlet.com/dharmasaranya3/xkgynid5rr8ap14z/wish/3482260717</link>
         <description><![CDATA[<p>PYLORIC MASS</p><p><br></p><p>BENIGN </p><p>Peptic ulcer citatrisation</p><p>Tricobazor</p><p>Superior Mesenteric vessel syndrome </p><p>Annular pancrease </p><p>Celiac lymphadenopathy </p><p><br></p><p>MALIGNANT</p><p>Gastric Carcinoma</p><p>Head of pancreas cancer</p><p>Infiltration of pylorus by Gall bladder and liver carcinoma</p><p><br></p><p><br></p><p>EPONYMS </p><p>Troisier ' s sign - Virchows node palpable</p><p>Sister joseph nodule</p><p>Krukenberg tumor</p><p>Blomers cell tumor</p><p>Stump carcinoma</p><p><br></p>]]></description>
         <enclosure url="" />
         <pubDate>2025-06-08 06:25:32 UTC</pubDate>
         <guid>https://padlet.com/dharmasaranya3/xkgynid5rr8ap14z/wish/3482260717</guid>
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         <title>After studying </title>
         <author></author>
         <link>https://padlet.com/dharmasaranya3/xkgynid5rr8ap14z/wish/3485364050</link>
         <description><![CDATA[<p>---Pyloric Mass ----</p><p>•Malignant Causes:</p><p>1. Gastric Adenocarcinoma(most common malignancy).  </p><p>2. Gastrointestinal Stromal Tumor (GIST)</p><p>3. Pancreatic Cancer (invading pylorus).  </p><p>4. Metastatic Tumors (e.g., melanoma, breast).  </p><p>5. Lymphoma(e.g., MALT lymphoma). </p><p>6. Pancreatic carcinoma</p><p>7. Gall bladder and biliary tract carcinoma</p><p><br></p><p>•Benign Causes: </p><p>1. Congenital hypertrophic Pyloric Stenosis ( in infants ).  </p><p>2. Peptic Ulcer Disease (chronic, with scarring/fibrosis leading to cicatisation ).  </p><p>3. Hyperplastic Polyps or Adenomas</p><p>4. Pancreatic  (Heterotopic Pancreas, annular pancreas)</p><p>5. TrichoBezoar(ingested hair mass).  </p><p>6. Inflammatory Pseudotumor </p><p><br></p><p> ---Eponyms---</p><p>1. Troisier's Sign  </p><p>   - Metastasis to left supraclavicular lymph node- Virchow's node </p><p><br></p><p>2. Krukenberg Tumor </p><p>   - Ovarian metastasis of  gastric cancer.  </p><p><br></p><p>3. Sister Mary Joseph Nodule</p><p>   - Periumbilical nodule from peritoneal metastasis.  </p><p><br></p><p>4. Blumer's Shelf</p><p>   - Rectal shelf palpable on exam due to peritoneal metastasis.  </p><p><br></p><p>5. Irish's Syndrome (Trifecta of Gastric Cancer)  </p><p>   - Acanthosis nigricans, hyperkeratosis, and tripe palms.  </p><p><br></p><p>6. Bormann Classification</p><p>   - Macroscopic growth patterns of gastric cancer (Types I–IV).  </p><p><br></p><p>7. Linitis Plastica ("Leather Bottle Stomach")  </p><p>8. Billroth I/II</p><p>   - Surgical reconstructions post-gastrectomy (not a tumor type, but associated management). </p><p>  9. Stump carcinoma- carcinoma due to bile reflex after 10-20 years after gastrojejnostomy</p>]]></description>
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         <pubDate>2025-06-10 14:58:14 UTC</pubDate>
         <guid>https://padlet.com/dharmasaranya3/xkgynid5rr8ap14z/wish/3485364050</guid>
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         <title></title>
         <author></author>
         <link>https://padlet.com/dharmasaranya3/xkgynid5rr8ap14z/wish/3489652884</link>
         <description><![CDATA[<p>1) Significance of mass in pyloric region</p><p>Gastric carcinoma(adenocarcinoma)</p><p>can cause gastric outlet obstruction (in late stage) - early satiety, epigastric fullness, weight loss, vomiting</p><p>palpable epigastric mass</p><p>2) Eponym of left supraclavicular lymphadenopathy - Virchow’s node</p><p>Irish node - left axillary lymphadenopathy</p><p>Blumer’s shelf - hard mass can be felt on rectal examination </p><p>Sister Mary Joseph nodule - periumblical nodule ( metastatic spread from gastric or ovarian cancer)</p><p>Krukenberg tumor - ovarian metastasis of gastric carcinoma</p>]]></description>
         <enclosure url="" />
         <pubDate>2025-06-13 15:39:48 UTC</pubDate>
         <guid>https://padlet.com/dharmasaranya3/xkgynid5rr8ap14z/wish/3489652884</guid>
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         <title></title>
         <author></author>
         <link>https://padlet.com/dharmasaranya3/xkgynid5rr8ap14z/wish/3490474560</link>
         <description><![CDATA[<p><br/></p><p>Pyloric obstruction  delayed gastric emptying</p><p>Early satiety, projectile vomiting, weight loss</p><p>Infiltrative tumors in the pylorus can spread to nearby structures</p><p>May present with epigastric fullness and succussion splash</p><p>Virchow’s node</p><p>Left supraclavicular lymph node</p><p>Sign of gastric carcinoma metastasis via thoracic duct drainage</p><p>Other eponyms used in gastric carcinoma clinical practice:</p><p>Eponym	Description</p><p>Sister Mary Joseph nodule	Periumbilical metastatic nodule usually from GI or ovarian cancer</p><p>Blumer’s shelf	Palpable mass on rectal exam  peritoneal metastasis</p><p>Irish node	Left axillary lymph node metastasis</p><p>Krukenberg tumor	Bilateral ovarian metastases from gastric adenocarcinoma</p><p><br/></p>]]></description>
         <enclosure url="" />
         <pubDate>2025-06-15 05:53:21 UTC</pubDate>
         <guid>https://padlet.com/dharmasaranya3/xkgynid5rr8ap14z/wish/3490474560</guid>
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         <title></title>
         <author></author>
         <link>https://padlet.com/dharmasaranya3/xkgynid5rr8ap14z/wish/3490474808</link>
         <description><![CDATA[<p>1. What is the significance of a mass in the pyloric region?</p><p>Pyloric obstruction → delayed gastric emptying</p><p>Early satiety, projectile vomiting, weight loss</p><p>Infiltrative tumors in the pylorus can spread to nearby structures</p><p>May present with epigastric fullness and succussion splash</p><p>---</p><p>2. What is the eponym of supraclavicular lymphadenopathy?</p><p>Virchow’s node</p><p>Left supraclavicular lymph node</p><p>Sign of gastric carcinoma metastasis via thoracic duct drainage</p><p>---</p><p>Other eponyms used in gastric carcinoma clinical practice:</p><p>Eponym	Description</p><p>Sister Mary Joseph nodule	Periumbilical metastatic nodule (usually from GI or ovarian cancer)</p><p>Blumer’s shelf	Palpable mass on rectal exam → peritoneal metastasis</p><p>Irish node	Left axillary lymph node metastasis</p><p>Krukenberg tumor	Bilateral ovarian metastases from gastric adenocarcinoma</p><p><br/></p>]]></description>
         <enclosure url="" />
         <pubDate>2025-06-15 05:54:32 UTC</pubDate>
         <guid>https://padlet.com/dharmasaranya3/xkgynid5rr8ap14z/wish/3490474808</guid>
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         <title>1. The mass can cause gastric outlet obstruction which causes the symptoms of the patient.</title>
         <author></author>
         <link>https://padlet.com/dharmasaranya3/xkgynid5rr8ap14z/wish/3491704098</link>
         <description><![CDATA[<p>Causes: cicatrisation of duodenal ulcer</p><p>               Distal CA stomach </p><p><br/></p><ol start="2"><li><p>Virchow node; other eponyms - Irish node, Sister Mary Joseph nodules </p></li></ol>]]></description>
         <enclosure url="" />
         <pubDate>2025-06-16 10:08:25 UTC</pubDate>
         <guid>https://padlet.com/dharmasaranya3/xkgynid5rr8ap14z/wish/3491704098</guid>
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