Reacciones Pericíclicas by López Vargas Miranda Michelle https://padlet.com/lopezmiranda/xfbqvka9xhqpkdek en-us 2024-10-05 03:53:15 UTC 2024-10-14 08:32:16 UTC hello@padlet.com Diseño de fármacos, 4FM1. Reacciones Pericíclicas. lopezmiranda https://padlet.com/lopezmiranda/xfbqvka9xhqpkdek/wish/3154350258 2024-10-05 04:08:06 UTC https://padlet.com/lopezmiranda/xfbqvka9xhqpkdek/wish/3154350258 cynthiaramos6996 https://padlet.com/lopezmiranda/xfbqvka9xhqpkdek/wish/3155724723 Ramos Pérez Cynthia Alejandra

https://www.canva.com/design/DAGSrJJatEg/y6wHGpvpYrCEC0iQtxKYcg/edit?utm_content=DAGSrJJatEg&utm_campaign=designshare&utm_medium=link2&utm_source=sharebutton

]]> 2024-10-06 20:55:00 UTC https://padlet.com/lopezmiranda/xfbqvka9xhqpkdek/wish/3155724723 mairaitzalonso11 https://padlet.com/lopezmiranda/xfbqvka9xhqpkdek/wish/3155974514 Alonso Martinez Maira Itzel

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]]> 2024-10-09 02:26:48 UTC https://padlet.com/lopezmiranda/xfbqvka9xhqpkdek/wish/3160225552 https://padlet.com/lopezmiranda/xfbqvka9xhqpkdek/wish/3160332399 Gonzalez Gonzalez Rodrigo Alexis

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]]> 2024-10-09 04:53:54 UTC https://padlet.com/lopezmiranda/xfbqvka9xhqpkdek/wish/3160383815 https://padlet.com/lopezmiranda/xfbqvka9xhqpkdek/wish/3161467181 FUENTES BARRERA ESTEFANÍA NARAYANI

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]]> 2024-10-11 06:34:15 UTC https://padlet.com/lopezmiranda/xfbqvka9xhqpkdek/wish/3164431734 sharonarlettcruz https://padlet.com/lopezmiranda/xfbqvka9xhqpkdek/wish/3164469332 Cruz Hernández Sharon Arlett

]]> 2024-10-11 07:04:58 UTC https://padlet.com/lopezmiranda/xfbqvka9xhqpkdek/wish/3164469332 coraymaacosta12 https://padlet.com/lopezmiranda/xfbqvka9xhqpkdek/wish/3164484216 Acosta Mesino Corayma

]]> 2024-10-11 07:16:19 UTC https://padlet.com/lopezmiranda/xfbqvka9xhqpkdek/wish/3164484216 https://padlet.com/lopezmiranda/xfbqvka9xhqpkdek/wish/3165404121 2024-10-11 20:40:04 UTC https://padlet.com/lopezmiranda/xfbqvka9xhqpkdek/wish/3165404121 https://padlet.com/lopezmiranda/xfbqvka9xhqpkdek/wish/3166953219 Las reacciones Periciclicas tienen una gran importancia en la industria farmaceutica debido a su alta eficiencia y selectividad en la formacion de enlaces, lo que facilita la sintesis de compuestos bioactivos complejos.


1.-SINTESIS DE MOLÉCULAS COMPLEJAS:

1.1 Permiten formar estructuras ciclicas, comunes en muchos farmacos, sin necesidad de catalizadores metalicos.

1.2 Ejemplo: la reaccion de Diels-Alder se utiliza para sintetizar anillos de seis miembros, presentes en esteroides, antibioticos, y antiinflamatorios.


2.-CONTROL ESTEREOESPECIFICO:

2.1 Facilitan la obtencion de productos con una configuracion estereoquimica específica, importante para la bioactividad de fármacos.

2.2 En la sintesis de medicamentos como prostaglandinas, es esencial controlar la geometria de los productos.


3.-MINIMIZACION DE SUBPRODUCTOS:

3.1 Al ser reacciones concertadas (transcurren sin intermediarios), disminuyen la formacion de subproductos, optimizando los proces. Esto reduce costos y facilita la purificacion de los compuestos activos.


4.-DESARROLLO DE NUEVOS MEDICAMENTOS:

4.1 Las reacciones periciclicas se utilizan en la síntesis de productos naturales y analogos que pueden tener actividad farmacologica, como alcaloides, antitumorales y antivirales.


LibreTexts Español. (s. f.). 21.11: Reacciones pericíclicas. LibreTexts. Recuperado el 13 de octubre de 2024, de https://espanol.libretexts.org






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García Bacilio Sergio

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