https://padlet.com/gregoretti668/x83q7hkpmuqnq8q1 en-us 2023-09-15 01:58:42 UTC 2023-10-12 22:09:37 UTC hello@padlet.com gregoretti668 https://padlet.com/gregoretti668/x83q7hkpmuqnq8q1/wish/2705116268 2023-09-15 01:59:56 UTC https://padlet.com/gregoretti668/x83q7hkpmuqnq8q1/wish/2705116268 gregoretti668 https://padlet.com/gregoretti668/x83q7hkpmuqnq8q1/wish/2705116756 blue = lecture]]> 2023-09-15 02:00:14 UTC https://padlet.com/gregoretti668/x83q7hkpmuqnq8q1/wish/2705116756 gregoretti668 https://padlet.com/gregoretti668/x83q7hkpmuqnq8q1/wish/2705117309 green = textbook]]> 2023-09-15 02:00:37 UTC https://padlet.com/gregoretti668/x83q7hkpmuqnq8q1/wish/2705117309 gregoretti668 https://padlet.com/gregoretti668/x83q7hkpmuqnq8q1/wish/2705117688 yellow = article]]> 2023-09-15 02:00:51 UTC https://padlet.com/gregoretti668/x83q7hkpmuqnq8q1/wish/2705117688 gregoretti668 https://padlet.com/gregoretti668/x83q7hkpmuqnq8q1/wish/2705120237 2023-09-15 02:02:33 UTC https://padlet.com/gregoretti668/x83q7hkpmuqnq8q1/wish/2705120237 gregoretti668 https://padlet.com/gregoretti668/x83q7hkpmuqnq8q1/wish/2705129213 - distribute motor fibers to effector organs (glands and muscles)
- collect somatosensory info to be passed to the brain
- some autonomy
> reflexive control circuits]]> 2023-09-15 02:08:02 UTC https://padlet.com/gregoretti668/x83q7hkpmuqnq8q1/wish/2705129213 gregoretti668 https://padlet.com/gregoretti668/x83q7hkpmuqnq8q1/wish/2705133938 2023-09-15 02:11:05 UTC https://padlet.com/gregoretti668/x83q7hkpmuqnq8q1/wish/2705133938 gregoretti668 https://padlet.com/gregoretti668/x83q7hkpmuqnq8q1/wish/2705145967 - spinal root: bundle of axons surrounded by connective tissue tat occurs in pair, fuse and form --> spinal nerve
- cauda equina: bundle of spinal roots located caudle to end of spinal cord
- caudal block: anesthesia and paralysis of lower part of body produced by injection of local anesthetic into cerebrospinal fluid surrounding the cauda equina]]> 2023-09-15 02:18:43 UTC https://padlet.com/gregoretti668/x83q7hkpmuqnq8q1/wish/2705145967 gregoretti668 https://padlet.com/gregoretti668/x83q7hkpmuqnq8q1/wish/2705147913 2023-09-15 02:19:55 UTC https://padlet.com/gregoretti668/x83q7hkpmuqnq8q1/wish/2705147913 gregoretti668 https://padlet.com/gregoretti668/x83q7hkpmuqnq8q1/wish/2705156937 - dorsal root: spinal root that contains incoming (afferent) sensory fibers
- ventral root: spinal root that contains incoming (efferent) motor fibers]]> 2023-09-15 02:26:02 UTC https://padlet.com/gregoretti668/x83q7hkpmuqnq8q1/wish/2705156937 gregoretti668 https://padlet.com/gregoretti668/x83q7hkpmuqnq8q1/wish/2705160685 meninges = 3 layers of SC and brain]]> 2023-09-15 02:28:15 UTC https://padlet.com/gregoretti668/x83q7hkpmuqnq8q1/wish/2705160685 gregoretti668 https://padlet.com/gregoretti668/x83q7hkpmuqnq8q1/wish/2705172472 - white matter: ascending and descending bundles of myelinated axons
- white matter in SC is on the outside
> opposite in brain where white matter is on the inside
- gray matter: neural cell bodies and short, unmyelinated axons
- gray matter in SC is on the inside]]> 2023-09-15 02:36:49 UTC https://padlet.com/gregoretti668/x83q7hkpmuqnq8q1/wish/2705172472 gregoretti668 https://padlet.com/gregoretti668/x83q7hkpmuqnq8q1/wish/2705176205 - dorsal (posterior) horns contain interneurons
> receive info from sensory neurons in dorsal root
> cell bodies in dorsal root ganglion
- ventral (anterior) horns contain motor neurons of somatic (voluntary) NS
> sends info out of ventral root]]> 2023-09-15 02:39:58 UTC https://padlet.com/gregoretti668/x83q7hkpmuqnq8q1/wish/2705176205 gregoretti668 https://padlet.com/gregoretti668/x83q7hkpmuqnq8q1/wish/2705179068 - gray matter surrounds central canal
- central canal is filed with CSF]]> 2023-09-15 02:41:14 UTC https://padlet.com/gregoretti668/x83q7hkpmuqnq8q1/wish/2705179068 gregoretti668 https://padlet.com/gregoretti668/x83q7hkpmuqnq8q1/wish/2705970012 2023-09-15 13:57:11 UTC https://padlet.com/gregoretti668/x83q7hkpmuqnq8q1/wish/2705970012 gregoretti668 https://padlet.com/gregoretti668/x83q7hkpmuqnq8q1/wish/2705979824 - nerve: bundle of neurons outside of CNS
- endoneurium: connective tissue sheath that surrounds each fiber; binds groups of fascicles
- perineurium: wraps groups of fibers bound into a fascicle]]> 2023-09-15 14:03:19 UTC https://padlet.com/gregoretti668/x83q7hkpmuqnq8q1/wish/2705979824 gregoretti668 https://padlet.com/gregoretti668/x83q7hkpmuqnq8q1/wish/2705982385 mixed nerves: both sensory and motor fibers
sensory (afferent) nerves: carries impulses to CNS
motor (efferent) nerves: carries impulses from CNS]]> 2023-09-15 14:04:45 UTC https://padlet.com/gregoretti668/x83q7hkpmuqnq8q1/wish/2705982385 gregoretti668 https://padlet.com/gregoretti668/x83q7hkpmuqnq8q1/wish/2706187448 - 12 pairs of nerves mostly for head and neck
- pair of vagus nerves extend to thoracic and abdominal cavities
- most nerves are mixed
- 3 sensory only nerves
> optic, olfactory, vestibulocochlear]]> 2023-09-15 16:45:00 UTC https://padlet.com/gregoretti668/x83q7hkpmuqnq8q1/wish/2706187448 gregoretti668 https://padlet.com/gregoretti668/x83q7hkpmuqnq8q1/wish/2706188676 2023-09-15 16:46:08 UTC https://padlet.com/gregoretti668/x83q7hkpmuqnq8q1/wish/2706188676 gregoretti668 https://padlet.com/gregoretti668/x83q7hkpmuqnq8q1/wish/2706193175 2023-09-15 16:50:26 UTC https://padlet.com/gregoretti668/x83q7hkpmuqnq8q1/wish/2706193175 gregoretti668 https://padlet.com/gregoretti668/x83q7hkpmuqnq8q1/wish/2706194680 2023-09-15 16:51:50 UTC https://padlet.com/gregoretti668/x83q7hkpmuqnq8q1/wish/2706194680 gregoretti668 https://padlet.com/gregoretti668/x83q7hkpmuqnq8q1/wish/2706195686 2023-09-15 16:52:52 UTC https://padlet.com/gregoretti668/x83q7hkpmuqnq8q1/wish/2706195686 gregoretti668 https://padlet.com/gregoretti668/x83q7hkpmuqnq8q1/wish/2706196850 2023-09-15 16:53:58 UTC https://padlet.com/gregoretti668/x83q7hkpmuqnq8q1/wish/2706196850 gregoretti668 https://padlet.com/gregoretti668/x83q7hkpmuqnq8q1/wish/2706215157 - spinal nerve: peripheral nerve attached to the spinal cord
- 31 pairs of spinal nerves
> combination of ventral and dorsal roots of SC]]> 2023-09-15 17:11:13 UTC https://padlet.com/gregoretti668/x83q7hkpmuqnq8q1/wish/2706215157 gregoretti668 https://padlet.com/gregoretti668/x83q7hkpmuqnq8q1/wish/2706222549 - PNS isn't protected (no skull, vertebrae, CSF)
- cranial & spinal nerves (except optic nerve) are in PNS
- cranial nerve cell bodies originate in the brain, but axons extend out of the skull]]> 2023-09-15 17:17:31 UTC https://padlet.com/gregoretti668/x83q7hkpmuqnq8q1/wish/2706222549 gregoretti668 https://padlet.com/gregoretti668/x83q7hkpmuqnq8q1/wish/2706228043 not divisions w/in somatic & autonomic]]> 2023-09-15 17:22:33 UTC https://padlet.com/gregoretti668/x83q7hkpmuqnq8q1/wish/2706228043 gregoretti668 https://padlet.com/gregoretti668/x83q7hkpmuqnq8q1/wish/2706229283 2023-09-15 17:23:37 UTC https://padlet.com/gregoretti668/x83q7hkpmuqnq8q1/wish/2706229283 gregoretti668 https://padlet.com/gregoretti668/x83q7hkpmuqnq8q1/wish/2706230842 2023-09-15 17:25:07 UTC https://padlet.com/gregoretti668/x83q7hkpmuqnq8q1/wish/2706230842 gregoretti668 https://padlet.com/gregoretti668/x83q7hkpmuqnq8q1/wish/2706236725 - ramus: branch of spinal nerve
>both motor and sensory fibers
- dorsal rami: serve the skin and muscles of posterior trunk
- ventral rami (T1-T12): intercostal nerves that supply muscles & skin of ribs & trunk
- ventral rami (except T1-T12): form complex of networks (plexus) for the anterior]]> 2023-09-15 17:30:46 UTC https://padlet.com/gregoretti668/x83q7hkpmuqnq8q1/wish/2706236725 gregoretti668 https://padlet.com/gregoretti668/x83q7hkpmuqnq8q1/wish/2706240645 - plexus: network of nerves serving motor and sensory needs of limbs
- formed from ventral rami of spinal nerves in cervical, lumbar, and sacral regions
- 4 plexuses
> cervical, brachial, lumbar, sacral]]> 2023-09-15 17:33:38 UTC https://padlet.com/gregoretti668/x83q7hkpmuqnq8q1/wish/2706240645 gregoretti668 https://padlet.com/gregoretti668/x83q7hkpmuqnq8q1/wish/2706241146 2023-09-15 17:34:05 UTC https://padlet.com/gregoretti668/x83q7hkpmuqnq8q1/wish/2706241146 gregoretti668 https://padlet.com/gregoretti668/x83q7hkpmuqnq8q1/wish/2706243240 2023-09-15 17:34:42 UTC https://padlet.com/gregoretti668/x83q7hkpmuqnq8q1/wish/2706243240 gregoretti668 https://padlet.com/gregoretti668/x83q7hkpmuqnq8q1/wish/2706244125 2023-09-15 17:35:32 UTC https://padlet.com/gregoretti668/x83q7hkpmuqnq8q1/wish/2706244125 gregoretti668 https://padlet.com/gregoretti668/x83q7hkpmuqnq8q1/wish/2706246406 2023-09-15 17:37:50 UTC https://padlet.com/gregoretti668/x83q7hkpmuqnq8q1/wish/2706246406 gregoretti668 https://padlet.com/gregoretti668/x83q7hkpmuqnq8q1/wish/2706251560 - lemniscal pathway: dorsal column-medial lemniscus pathway (DCML); sensory pathway of the CNS
> fine touch, vibration, pressure, proprioception
- spinothamalic pathway
- corticospinal pathway

]]> 2023-09-15 17:42:48 UTC https://padlet.com/gregoretti668/x83q7hkpmuqnq8q1/wish/2706251560 gregoretti668 https://padlet.com/gregoretti668/x83q7hkpmuqnq8q1/wish/2706256191 - dorsal column-medial lemniscus pathway (DCML)
- sensory pathway of the CNS
> fine touch, vibration, pressure, proprioception]]> 2023-09-15 17:46:48 UTC https://padlet.com/gregoretti668/x83q7hkpmuqnq8q1/wish/2706256191 gregoretti668 https://padlet.com/gregoretti668/x83q7hkpmuqnq8q1/wish/2706266828 - transmit info from body by primary somatosensory cortex
- receives info from sensory receptors throughout the body
- carried through nerve tract in white matter of dorsal column of the SC to the
>> medulla
>> medial lemniscus
>> thalamus
>> internal capsule
>> somatosensory cortex]]> 2023-09-15 17:56:38 UTC https://padlet.com/gregoretti668/x83q7hkpmuqnq8q1/wish/2706266828 gregoretti668 https://padlet.com/gregoretti668/x83q7hkpmuqnq8q1/wish/2706268104 - two adjacent pathways
> anterior
>> carries info about crude touch
> lateral
>> carries info abt pain and temperature

- spinothalamic tract in SC has somatotopic organization]]> 2023-09-15 17:57:55 UTC https://padlet.com/gregoretti668/x83q7hkpmuqnq8q1/wish/2706268104 gregoretti668 https://padlet.com/gregoretti668/x83q7hkpmuqnq8q1/wish/2707074597 - neurons in this tract are mainly from nucleus proprius in laminae III and IV or dorsal horn
- axons of these neurons cross obliquely via ventral white commissure to enter the contra-lateral white matter where they ascend in the lateral funic-ulus]]> 2023-09-16 23:37:13 UTC https://padlet.com/gregoretti668/x83q7hkpmuqnq8q1/wish/2707074597 gregoretti668 https://padlet.com/gregoretti668/x83q7hkpmuqnq8q1/wish/2707075923 - pyramidal tract
- major neuronal pathway providing info necessary for voluntary motor fxn
- connects cortex and SC to the muscles for necessary movement]]> 2023-09-16 23:40:34 UTC https://padlet.com/gregoretti668/x83q7hkpmuqnq8q1/wish/2707075923 gregoretti668 https://padlet.com/gregoretti668/x83q7hkpmuqnq8q1/wish/2707076168 - lateral corticospinal tract axons weave out of tract into anterior horns of SC
- corticospinal tract controls fine movements of ipsilateral (same side of body) limbs, but corresponding motor cortex is contralateral
> distal to pyramidal decussation
- anterior corticospinal tract controls central axial and girdle muscles

]]> 2023-09-16 23:40:57 UTC https://padlet.com/gregoretti668/x83q7hkpmuqnq8q1/wish/2707076168 gregoretti668 https://padlet.com/gregoretti668/x83q7hkpmuqnq8q1/wish/2710880513 - separate from tracts that originate in the cortex
- originates in the BS
- carries motor fibers to SC
- involuntary movement]]> 2023-09-19 13:49:30 UTC https://padlet.com/gregoretti668/x83q7hkpmuqnq8q1/wish/2710880513 gregoretti668 https://padlet.com/gregoretti668/x83q7hkpmuqnq8q1/wish/2710920811 ganglia: clusters and bundles of neuronal tracts that come off the SC
peripheral nervous system ONLY]]> 2023-09-19 14:09:04 UTC https://padlet.com/gregoretti668/x83q7hkpmuqnq8q1/wish/2710920811 gregoretti668 https://padlet.com/gregoretti668/x83q7hkpmuqnq8q1/wish/2710934820 mininges: 3 protective layers in NS
goal: protect, allow everything in NS to stick together, make space for CSF to flow]]> 2023-09-19 14:15:42 UTC https://padlet.com/gregoretti668/x83q7hkpmuqnq8q1/wish/2710934820 gregoretti668 https://padlet.com/gregoretti668/x83q7hkpmuqnq8q1/wish/2710942268 nerve: PNS
neuron: CNS]]> 2023-09-19 14:19:40 UTC https://padlet.com/gregoretti668/x83q7hkpmuqnq8q1/wish/2710942268 gregoretti668 https://padlet.com/gregoretti668/x83q7hkpmuqnq8q1/wish/2710978558 branching happens after nerves leave the dorsal/ventral roots]]> 2023-09-19 14:37:40 UTC https://padlet.com/gregoretti668/x83q7hkpmuqnq8q1/wish/2710978558 gregoretti668 https://padlet.com/gregoretti668/x83q7hkpmuqnq8q1/wish/2711014243 - questions abt cranial nerves
> person presents this, what cranial nerves? or what SC nerve?
- questions will be clinical, case study
- get familiar w/ diagrams]]> 2023-09-19 14:55:22 UTC https://padlet.com/gregoretti668/x83q7hkpmuqnq8q1/wish/2711014243 gregoretti668 https://padlet.com/gregoretti668/x83q7hkpmuqnq8q1/wish/2719654618 parasympathetic and sympathetic states of of autonomic]]> 2023-09-25 16:29:17 UTC https://padlet.com/gregoretti668/x83q7hkpmuqnq8q1/wish/2719654618 gregoretti668 https://padlet.com/gregoretti668/x83q7hkpmuqnq8q1/wish/2719657548 - motor neurons originate in the CNS
- axons extend to skeletal muscles]]> 2023-09-25 16:31:15 UTC https://padlet.com/gregoretti668/x83q7hkpmuqnq8q1/wish/2719657548 gregoretti668 https://padlet.com/gregoretti668/x83q7hkpmuqnq8q1/wish/2719660444 - chain of 2 motor neurons
> preganglionic neurons in brain and SC
> postganglionic neurons extends to organs
- 2 arms
> sympathetic and parasymp divisions]]> 2023-09-25 16:33:06 UTC https://padlet.com/gregoretti668/x83q7hkpmuqnq8q1/wish/2719660444 gregoretti668 https://padlet.com/gregoretti668/x83q7hkpmuqnq8q1/wish/2719675942 - organs serves by autonomic NS get nerve fibers from symp and parasymp divisions
- exceptions only get symp fibers
> blood vessels, skin structures, some glands, and adrenal medulla]]> 2023-09-25 16:42:57 UTC https://padlet.com/gregoretti668/x83q7hkpmuqnq8q1/wish/2719675942 gregoretti668 https://padlet.com/gregoretti668/x83q7hkpmuqnq8q1/wish/2719680339 division that serve the same organ cause antagonistic effects bc of diff NT]]> 2023-09-25 16:45:07 UTC https://padlet.com/gregoretti668/x83q7hkpmuqnq8q1/wish/2719680339 gregoretti668 https://padlet.com/gregoretti668/x83q7hkpmuqnq8q1/wish/2719682181 postganglionic (adrenergic) fibers release norepinephrine]]> 2023-09-25 16:46:21 UTC https://padlet.com/gregoretti668/x83q7hkpmuqnq8q1/wish/2719682181 gregoretti668 https://padlet.com/gregoretti668/x83q7hkpmuqnq8q1/wish/2719683868 parasymp (cholinergic) fibers release acetylecholine]]> 2023-09-25 16:47:22 UTC https://padlet.com/gregoretti668/x83q7hkpmuqnq8q1/wish/2719683868 gregoretti668 https://padlet.com/gregoretti668/x83q7hkpmuqnq8q1/wish/2719684599 preganglionic axon in both release acetycholine]]> 2023-09-25 16:47:52 UTC https://padlet.com/gregoretti668/x83q7hkpmuqnq8q1/wish/2719684599 gregoretti668 https://padlet.com/gregoretti668/x83q7hkpmuqnq8q1/wish/2719694534 - response to unusual stimulus when emotionally or physically stress or threatened
- increases activity
- E division
> Exercise
> Excitement
> Emergency
> Embarrassment]]> 2023-09-25 16:54:04 UTC https://padlet.com/gregoretti668/x83q7hkpmuqnq8q1/wish/2719694534 gregoretti668 https://padlet.com/gregoretti668/x83q7hkpmuqnq8q1/wish/2719697454 - rest and digest
- conserve energy
- D division
> digestion
> defecation
> diuresis]]> 2023-09-25 16:55:56 UTC https://padlet.com/gregoretti668/x83q7hkpmuqnq8q1/wish/2719697454 gregoretti668 https://padlet.com/gregoretti668/x83q7hkpmuqnq8q1/wish/2719702940 - preganglionic neurons originate:
> cranial nerves 3, 7, 9, 10
> S₂ to S₄ regions of SC
- preganglionic neurons synapse w terminal ganglia
- then postganglionic axons extend to organs served]]> 2023-09-25 16:59:25 UTC https://padlet.com/gregoretti668/x83q7hkpmuqnq8q1/wish/2719702940 gregoretti668 https://padlet.com/gregoretti668/x83q7hkpmuqnq8q1/wish/2719707127 - preganglionic neurons originate T₁ to L_2
- axons pass through ramus communicans to enter sympathetic trunk ganglion
- sympathetic trunk or chains near the SC]]> 2023-09-25 17:02:13 UTC https://padlet.com/gregoretti668/x83q7hkpmuqnq8q1/wish/2719707127 gregoretti668 https://padlet.com/gregoretti668/x83q7hkpmuqnq8q1/wish/2719708607 2023-09-25 17:03:07 UTC https://padlet.com/gregoretti668/x83q7hkpmuqnq8q1/wish/2719708607 gregoretti668 https://padlet.com/gregoretti668/x83q7hkpmuqnq8q1/wish/2719709727 2023-09-25 17:03:44 UTC https://padlet.com/gregoretti668/x83q7hkpmuqnq8q1/wish/2719709727 gregoretti668 https://padlet.com/gregoretti668/x83q7hkpmuqnq8q1/wish/2719766512 DOI = amphetamine 1-(2,5-dimethoxy-4-iodophenyl)-2-aminopropane ]]> 2023-09-25 17:40:41 UTC https://padlet.com/gregoretti668/x83q7hkpmuqnq8q1/wish/2719766512 gregoretti668 https://padlet.com/gregoretti668/x83q7hkpmuqnq8q1/wish/2719776483 - most psychedelic pharmacology focuses on male mice
> measure head twitch behavior (HTB) in male and female after DOI]]> 2023-09-25 17:47:20 UTC https://padlet.com/gregoretti668/x83q7hkpmuqnq8q1/wish/2719776483 gregoretti668 https://padlet.com/gregoretti668/x83q7hkpmuqnq8q1/wish/2719779138 more HTR in female vs male C57BL/6Jmice, not in 129S6/SvEv mice]]> 2023-09-25 17:49:06 UTC https://padlet.com/gregoretti668/x83q7hkpmuqnq8q1/wish/2719779138 gregoretti668 https://padlet.com/gregoretti668/x83q7hkpmuqnq8q1/wish/2719781891 Volinanserin / M100907 is a 5-HT2AR antagonist 
> fully prevented DOI-induced HTR in male and female C57BL/6J mice ]]> 2023-09-25 17:50:50 UTC https://padlet.com/gregoretti668/x83q7hkpmuqnq8q1/wish/2719781891 gregoretti668 https://padlet.com/gregoretti668/x83q7hkpmuqnq8q1/wish/2719785314 accumulated IP1 (inositol monophosphate) in frontal cortex upon DOI administration --> no sex-related effects ]]> 2023-09-25 17:53:02 UTC https://padlet.com/gregoretti668/x83q7hkpmuqnq8q1/wish/2719785314 gregoretti668 https://padlet.com/gregoretti668/x83q7hkpmuqnq8q1/wish/2719789007 brain and plasma concentration of DOI lower 30 and 60 mins after drug admin in female vs male]]> 2023-09-25 17:55:14 UTC https://padlet.com/gregoretti668/x83q7hkpmuqnq8q1/wish/2719789007 gregoretti668 https://padlet.com/gregoretti668/x83q7hkpmuqnq8q1/wish/2720143609 - most immediate and acute effects of psychedelic administration is mediated by 5-HT_2ARs
> especially in forebrain pyramidal neurons
- other monoaminergic G-protein-coupled receptors (GPCRs) also may be relevant to hallucinogenic effects
> 5-HT_1A, serotonin 5-HT_5A, dopamine D₂ ]]> 2023-09-26 00:21:32 UTC https://padlet.com/gregoretti668/x83q7hkpmuqnq8q1/wish/2720143609 gregoretti668 https://padlet.com/gregoretti668/x83q7hkpmuqnq8q1/wish/2720217141 2023-09-26 01:13:50 UTC https://padlet.com/gregoretti668/x83q7hkpmuqnq8q1/wish/2720217141 gregoretti668 https://padlet.com/gregoretti668/x83q7hkpmuqnq8q1/wish/2720237018 IP is a downstream effector of G q/11 signaling 
test IP accumulation in frontal cortex
no sex related differences]]> 2023-09-26 01:26:50 UTC https://padlet.com/gregoretti668/x83q7hkpmuqnq8q1/wish/2720237018 gregoretti668 https://padlet.com/gregoretti668/x83q7hkpmuqnq8q1/wish/2720262533 2023-09-26 01:44:36 UTC https://padlet.com/gregoretti668/x83q7hkpmuqnq8q1/wish/2720262533 gregoretti668 https://padlet.com/gregoretti668/x83q7hkpmuqnq8q1/wish/2721323286 DOI is the psychedelic]]> 2023-09-26 14:04:48 UTC https://padlet.com/gregoretti668/x83q7hkpmuqnq8q1/wish/2721323286 gregoretti668 https://padlet.com/gregoretti668/x83q7hkpmuqnq8q1/wish/2721334593 parts of mice that are involved in HTR:
cervical plexus control
cranial nerve 6]]> 2023-09-26 14:10:35 UTC https://padlet.com/gregoretti668/x83q7hkpmuqnq8q1/wish/2721334593 gregoretti668 https://padlet.com/gregoretti668/x83q7hkpmuqnq8q1/wish/2721352942 C57 is more active, 129 is more docile]]> 2023-09-26 14:19:16 UTC https://padlet.com/gregoretti668/x83q7hkpmuqnq8q1/wish/2721352942 gregoretti668 https://padlet.com/gregoretti668/x83q7hkpmuqnq8q1/wish/2721389447 if there is a difference btwn C57 and 129 outcomes from an experiment, we can say that it's based on their genetic differences]]> 2023-09-26 14:37:41 UTC https://padlet.com/gregoretti668/x83q7hkpmuqnq8q1/wish/2721389447 gregoretti668 https://padlet.com/gregoretti668/x83q7hkpmuqnq8q1/wish/2721679074 - DCML and spinothalamic are sensory
> from body into CNS via SC > brainstem > forebrain
- corticospinal is motor
> down neuraxis > muscle contractions

DRG = dorsal root ganglia
DCN = dorsal column nuclei]]> 2023-09-26 17:22:21 UTC https://padlet.com/gregoretti668/x83q7hkpmuqnq8q1/wish/2721679074 gregoretti668 https://padlet.com/gregoretti668/x83q7hkpmuqnq8q1/wish/2721761967 2023-09-26 18:12:49 UTC https://padlet.com/gregoretti668/x83q7hkpmuqnq8q1/wish/2721761967 gregoretti668 https://padlet.com/gregoretti668/x83q7hkpmuqnq8q1/wish/2721800005 - perception of of light touch simulate afferent neurons that have cell body in DRG
- sends axon into SC that ascend through dorsal column of SC to DCN in medulla
- then neuron crosses midline, and axon continues to ascend contralateral to medulla mid line to thalamus
--> !!! lemniscus pathway always end on opposite side of body that is started on
- thalamic neuron receive info than send an axon via somatosensory radiation to primary somatosensory cortex

]]> 2023-09-26 18:36:00 UTC https://padlet.com/gregoretti668/x83q7hkpmuqnq8q1/wish/2721800005 gregoretti668 https://padlet.com/gregoretti668/x83q7hkpmuqnq8q1/wish/2721807941 minimum four neurons: primary afferent, dorsal column nuclear cell, thalamic neuron, and cortical neuron
minimum three synapses]]> 2023-09-26 18:41:13 UTC https://padlet.com/gregoretti668/x83q7hkpmuqnq8q1/wish/2721807941 gregoretti668 https://padlet.com/gregoretti668/x83q7hkpmuqnq8q1/wish/2721827449 - primary afferent nociceptors and thermoreceptors synapse on SC neurons in dorsal horn
- DHC neuron is a spinothalamic tract cell
- spinothalamic tract cell sends its axon to across the midline to continue up the spinothalamic tract to the thalamus
- spinothalamic tract axons travel in ventrolateral quadrant of SC
- spinothalamic neuron synapses thalamic neuron then sends info to primary somatosensory cortex]]> 2023-09-26 18:54:32 UTC https://padlet.com/gregoretti668/x83q7hkpmuqnq8q1/wish/2721827449 gregoretti668 https://padlet.com/gregoretti668/x83q7hkpmuqnq8q1/wish/2721829899 axons of corticospinal tract travel through forebrain, midbrain, and pons --> forms pyramids --> 2 parallel columns down either side of the ventral medullary midline]]> 2023-09-26 18:56:20 UTC https://padlet.com/gregoretti668/x83q7hkpmuqnq8q1/wish/2721829899 gregoretti668 https://padlet.com/gregoretti668/x83q7hkpmuqnq8q1/wish/2721835317 2023-09-26 19:00:07 UTC https://padlet.com/gregoretti668/x83q7hkpmuqnq8q1/wish/2721835317 gregoretti668 https://padlet.com/gregoretti668/x83q7hkpmuqnq8q1/wish/2721837819 corticospinal tract starts on opposite side of the muscles it influence

motor or pyramidal decussation: where corticospinal tract fibers cross (decussation)]]> 2023-09-26 19:01:58 UTC https://padlet.com/gregoretti668/x83q7hkpmuqnq8q1/wish/2721837819 gregoretti668 https://padlet.com/gregoretti668/x83q7hkpmuqnq8q1/wish/2721855902 nerves: peripheral bundles of axons
roots: central bundles of axons that carry axons btw the CNS and the exit pt from the dural envelope

- spinal nerves have both sensory fibers ending in the SC and motor axons beginning in the SC]]> 2023-09-26 19:11:26 UTC https://padlet.com/gregoretti668/x83q7hkpmuqnq8q1/wish/2721855902 gregoretti668 https://padlet.com/gregoretti668/x83q7hkpmuqnq8q1/wish/2721860784 2023-09-26 19:15:19 UTC https://padlet.com/gregoretti668/x83q7hkpmuqnq8q1/wish/2721860784 gregoretti668 https://padlet.com/gregoretti668/x83q7hkpmuqnq8q1/wish/2721862812 2023-09-26 19:16:57 UTC https://padlet.com/gregoretti668/x83q7hkpmuqnq8q1/wish/2721862812 gregoretti668 https://padlet.com/gregoretti668/x83q7hkpmuqnq8q1/wish/2721886746 2023-09-26 19:37:01 UTC https://padlet.com/gregoretti668/x83q7hkpmuqnq8q1/wish/2721886746 gregoretti668 https://padlet.com/gregoretti668/x83q7hkpmuqnq8q1/wish/2721895293 dermatome: spinal segment whose corresponding skin region's sensory info travels to]]> 2023-09-26 19:44:19 UTC https://padlet.com/gregoretti668/x83q7hkpmuqnq8q1/wish/2721895293 gregoretti668 https://padlet.com/gregoretti668/x83q7hkpmuqnq8q1/wish/2721898391 T1-L2 = sympathetic preganglionic neurons
S2 - S4 = parasympathetic preganglionic neurons]]> 2023-09-26 19:47:17 UTC https://padlet.com/gregoretti668/x83q7hkpmuqnq8q1/wish/2721898391 gregoretti668 https://padlet.com/gregoretti668/x83q7hkpmuqnq8q1/wish/2721912684 - sympathetic preganglionic neuron are in intermediolateral cell column (IML) = intermediate horn (IH)
 > intermediate gray column of cells
- parasympathetic preganglionic neurons in the sacral autonomic nucleus
> send their axons out the ventral roots to parasympathetic ganglia in target organ]]> 2023-09-26 20:00:04 UTC https://padlet.com/gregoretti668/x83q7hkpmuqnq8q1/wish/2721912684