Shar Pei by ALEXIS JEWELL https://padlet.com/arj0569/x1qkulrx36e6 How the protein’s structure is changed en-us 2019-03-07 15:16:44 UTC 2024-07-15 09:55:04 UTC hello@padlet.com How is the structure changed by this mutation? arj0569 https://padlet.com/arj0569/x1qkulrx36e6/wish/338904489 The affected protein in the Shar Pei dog is HAS2 (hyaluronan synthase 2). HAS2 is an enzyme that sits in the membrane of skin cells. It builds a large molecule called hyaluronan (HA) and releases it outside the cell.
 
HA surrounds skin cells to provide structural support. It is also a signaling molecule. HA tells skin cells to divide, and it guides moving cells to their proper place during development and wound healing.]]> 2019-03-07 15:26:03 UTC https://padlet.com/arj0569/x1qkulrx36e6/wish/338904489 How is the structure changed by this mutation? arj0569 https://padlet.com/arj0569/x1qkulrx36e6/wish/338907403 The affected protein in the Shar Pei dog is HAS2 (hyaluronan synthase 2). HAS2 is an enzyme that sits in the membrane of skin cells. It builds a large molecule called hyaluronan (HA) and releases it outside the cell.
 
HA surrounds skin cells to provide structural support. It is also a signaling molecule. HA tells skin cells to divide, and it guides moving cells to their proper place during development and wound healing.]]> 2019-03-07 15:30:49 UTC https://padlet.com/arj0569/x1qkulrx36e6/wish/338907403