Exam 1 by Neuro430 https://padlet.com/Neurophysiology/wytxdki02s9i Discussion en-us 2018-02-13 22:31:03 UTC 2025-12-06 15:08:20 UTC hello@padlet.com 1. How is the resting membrane potential of a neuron established? Knowing this how can one easily manipulate it? (5pt) Neurophysiology https://padlet.com/Neurophysiology/wytxdki02s9i/wish/232083627 NOTE: Na/K-ATPase pump is cited from lecture dated 1.21.18. Concentration gradient and selective permeability cited from lecture dated 1.16.18 (slide 7)]]> 2018-02-15 18:47:55 UTC https://padlet.com/Neurophysiology/wytxdki02s9i/wish/232083627 3. Define the following terms: (5pts) Neurophysiology https://padlet.com/Neurophysiology/wytxdki02s9i/wish/232167214 Depolarization: 
Hyperpolarization: 
Excitation:
Inhibition:
Reversal potential:

NOTE: Cited from lecture dated 1.21.18 and Wiki (for reversal potential)]]> 2018-02-15 21:36:28 UTC https://padlet.com/Neurophysiology/wytxdki02s9i/wish/232167214 2. What are 2 constants that effect the spread of electric potentials through passive membranes? Explain what information they can tell you about a neuron. (5pts) Neurophysiology https://padlet.com/Neurophysiology/wytxdki02s9i/wish/232177998 2018-02-15 22:18:29 UTC https://padlet.com/Neurophysiology/wytxdki02s9i/wish/232177998 9. UPDATED List 5 properties that are associated with a ligand-gated channel (think simple, feel free to draw a diagram and provide labels to help you)? (5pts) Neurophysiology https://padlet.com/Neurophysiology/wytxdki02s9i/wish/232178892 Cited from lecture 2.1.18]]> 2018-02-15 22:21:53 UTC https://padlet.com/Neurophysiology/wytxdki02s9i/wish/232178892 7. Propose a mechanism for the effect of muscarine on this neuron below. (2pts) Neurophysiology https://padlet.com/Neurophysiology/wytxdki02s9i/wish/232180892 Cited from lecture dated 1.25.18]]> 2018-02-15 22:29:44 UTC https://padlet.com/Neurophysiology/wytxdki02s9i/wish/232180892 4. Here is a voltage plot of an action potential. (5pts) Neurophysiology https://padlet.com/Neurophysiology/wytxdki02s9i/wish/232531468 Materials cited from lecture dated 1.18.18]]> 2018-02-16 22:49:58 UTC https://padlet.com/Neurophysiology/wytxdki02s9i/wish/232531468 5. What portion of the above voltage plot plays an important role in determining the ability of a neuron to fire another action potential? Provide an example of how a neuron can manipulate this phase to decrease its firing rate? (5pts) Neurophysiology https://padlet.com/Neurophysiology/wytxdki02s9i/wish/232532583 Cited from lecture dated 1.21.18]]> 2018-02-16 23:03:57 UTC https://padlet.com/Neurophysiology/wytxdki02s9i/wish/232532583 6. Here is an I/V plot for a novel cation channel (3pts). Neurophysiology https://padlet.com/Neurophysiology/wytxdki02s9i/wish/233018913 At what potential does the channel begin to activate?
Where is this channels reversal potential?
Which one of the following channels is best described by this plot?]]> 2018-02-19 18:40:55 UTC https://padlet.com/Neurophysiology/wytxdki02s9i/wish/233018913 8. Below is a recording of a train of action potential that were recorded a different distances along the dendrite following a somatic current injection. Why does the amplitude of the action potentials diminish so rapidly as you travel further away from the soma? (5pts) Neurophysiology https://padlet.com/Neurophysiology/wytxdki02s9i/wish/234570996 2018-02-23 04:15:30 UTC https://padlet.com/Neurophysiology/wytxdki02s9i/wish/234570996 10. Using the graph below, illustrate the I/V curves for the following types of channels: (3pts) Neurophysiology https://padlet.com/Neurophysiology/wytxdki02s9i/wish/234571099 A. Inward rectifying channel
B. Outward rectifying channel
C. Non rectifying channel
Cited from lecture 1.30.2018]]> 2018-02-23 04:16:48 UTC https://padlet.com/Neurophysiology/wytxdki02s9i/wish/234571099 11. Describe channel desensitization. (2pts) Neurophysiology https://padlet.com/Neurophysiology/wytxdki02s9i/wish/234571198 Cited from lecture 1.30.18]]> 2018-02-23 04:18:09 UTC https://padlet.com/Neurophysiology/wytxdki02s9i/wish/234571198 12. Propose two different models for how mechanosensitive channels can be gated (2pts) Neurophysiology https://padlet.com/Neurophysiology/wytxdki02s9i/wish/234571263 Cite from lecture dated 2.1.18]]> 2018-02-23 04:18:38 UTC https://padlet.com/Neurophysiology/wytxdki02s9i/wish/234571263 13. Provide a diagram illustrating each type of inhibition of a ligand-gated channel. (3pts) Neurophysiology https://padlet.com/Neurophysiology/wytxdki02s9i/wish/234571408 A. Competitive inhibition
B. Noncompetitive inhibition
C. pore block
Cited from lecture dated 2.6.18 & from Wikispaces]]> 2018-02-23 04:19:54 UTC https://padlet.com/Neurophysiology/wytxdki02s9i/wish/234571408 Final Exam Version https://padlet.com/Neurophysiology/wytxdki02s9i/wish/235056008 2018-02-25 07:08:04 UTC https://padlet.com/Neurophysiology/wytxdki02s9i/wish/235056008