https://padlet.com/kahlia7347/wsqct0a15ix2 Four Mechanisms en-us 2018-04-25 02:42:23 UTC 2026-03-16 18:50:13 UTC hello@padlet.com kahlia7347 https://padlet.com/kahlia7347/wsqct0a15ix2/wish/255081435 Elevated BGL      ---->        NADPH Decreses       -------->           X Produce Glutathione (antioxidant)        =         Cell Damage from Oxidative Stress]]> 2018-04-25 02:52:29 UTC https://padlet.com/kahlia7347/wsqct0a15ix2/wish/255081435 kahlia7347 https://padlet.com/kahlia7347/wsqct0a15ix2/wish/255082700 Glucose   *reacts with*   proteins  =     protein glycation  -----> Early Glycosylation Products (normal)

Chronic Hyperglycaemia   --->  Early Glycosylation Products ------> Irreversible reaction   =  AGEs  ---> releases inflammatory cytokines  = Vascular damage]]> 2018-04-25 03:02:25 UTC https://padlet.com/kahlia7347/wsqct0a15ix2/wish/255082700 kahlia7347 https://padlet.com/kahlia7347/wsqct0a15ix2/wish/255083476 Increased BGL -----> Increased synthesis DAG -------> Relates to Vasocrintriction = Blood Flow Abnormality = Endothelial Dysfunction]]> 2018-04-25 03:08:44 UTC https://padlet.com/kahlia7347/wsqct0a15ix2/wish/255083476 kahlia7347 https://padlet.com/kahlia7347/wsqct0a15ix2/wish/255083779 Increased BGL + Excess Fatty Acid Oxidation -----> Altering Enzymes + Proteins = Damage effect on Endothelial and Smooth Muscle Cells]]> 2018-04-25 03:11:39 UTC https://padlet.com/kahlia7347/wsqct0a15ix2/wish/255083779