ALS by Zabrina Rodriguez https://padlet.com/zabrinarodriguez/wgup6ajcane90643 ALC Concept Map en-us 2022-06-07 13:17:54 UTC 2022-06-07 13:53:08 UTC hello@padlet.com (ALS) Amyotrophic Lateral Sclerosis zabrinarodriguez https://padlet.com/zabrinarodriguez/wgup6ajcane90643/wish/2213626601 2022-06-07 13:27:18 UTC https://padlet.com/zabrinarodriguez/wgup6ajcane90643/wish/2213626601 A rare progressive neuromuscular disorder where motor nerves in the brainstem and spinal cord gradually degenerate. zabrinarodriguez https://padlet.com/zabrinarodriguez/wgup6ajcane90643/wish/2213629460 2022-06-07 13:29:32 UTC https://padlet.com/zabrinarodriguez/wgup6ajcane90643/wish/2213629460 Signs & Symptoms: zabrinarodriguez https://padlet.com/zabrinarodriguez/wgup6ajcane90643/wish/2213633843 Progressive muscle weakness and atrophy.
Often "limb-onset" weakness initially.
Trouble with fine motor skills.
Slurred speech and difficulty swallowing in "bulbar onset."
Muscle wasting, involuntary contractions, pain, sleep disorders, spasticity, hyperreflexia, drooling, emotional lability, constipation, esophageal reflux.

]]> 2022-06-07 13:33:06 UTC https://padlet.com/zabrinarodriguez/wgup6ajcane90643/wish/2213633843 Treatment Options: zabrinarodriguez https://padlet.com/zabrinarodriguez/wgup6ajcane90643/wish/2213639126 There is no cure.]]> 2022-06-07 13:37:13 UTC https://padlet.com/zabrinarodriguez/wgup6ajcane90643/wish/2213639126 Riluzole (Rilutek) zabrinarodriguez https://padlet.com/zabrinarodriguez/wgup6ajcane90643/wish/2213642027 Slows the progression. This drug reduces damage to motor neurons by decreasing the release of glutamate(an excitatory neurotransmitter) in the brain.]]> 2022-06-07 13:39:34 UTC https://padlet.com/zabrinarodriguez/wgup6ajcane90643/wish/2213642027 Edaravone (Radicava) zabrinarodriguez https://padlet.com/zabrinarodriguez/wgup6ajcane90643/wish/2213646066 Given via IV for 14 days, followed by 14 day rest period.
MOA: Edaravone is a free radical scavenger believed to relieve effects of oxidative stress, which is a likely factor in the progression of ALS.]]> 2022-06-07 13:42:46 UTC https://padlet.com/zabrinarodriguez/wgup6ajcane90643/wish/2213646066 Cause: Unknown zabrinarodriguez https://padlet.com/zabrinarodriguez/wgup6ajcane90643/wish/2213649520 About 5-10% of cases are genetic.
C9ORF72 mutation]]> 2022-06-07 13:45:35 UTC https://padlet.com/zabrinarodriguez/wgup6ajcane90643/wish/2213649520 Outcome: zabrinarodriguez https://padlet.com/zabrinarodriguez/wgup6ajcane90643/wish/2213651894 Death usually occurs within 2-5 years of diagnosis.]]> 2022-06-07 13:47:32 UTC https://padlet.com/zabrinarodriguez/wgup6ajcane90643/wish/2213651894 Signs and Symptoms: zabrinarodriguez https://padlet.com/zabrinarodriguez/wgup6ajcane90643/wish/2213655078 ALS does not affect intelligence. The patient remains cognitively intact but may experience depression and problems with decision making and memory.]]> 2022-06-07 13:49:54 UTC https://padlet.com/zabrinarodriguez/wgup6ajcane90643/wish/2213655078 Nursing Interventions: zabrinarodriguez https://padlet.com/zabrinarodriguez/wgup6ajcane90643/wish/2213658555 Facilitate communication.
Reduce aspiration risk.
Early identification of respiratory insufficiency.
Decrease pain from muscle weakness.
Decrease risk for fall related injuries.
Provide diversional activities.

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