ARDS (TH1) by Pauline Wong https://padlet.com/paulinewong1/w7il772hw2jkf3b6 NUR5923 Respiratory Pathophysiology en-us 2023-03-08 00:28:59 UTC 2023-06-03 14:44:12 UTC hello@padlet.com Instructions paulinewong1 https://padlet.com/paulinewong1/w7il772hw2jkf3b6/wish/2507722518
  • Choose a spokesperson
  • All students in the group are to work on all of the following questions/sections included in the Padlet
  • You can use diagrams/images other visual resources to explain each respiratory condition.
  • When we come back to the whole class, the spokesperson will feedback the groups findings, with the teams support
    • ]]>     2023-03-08 00:28:59 UTC https://padlet.com/paulinewong1/w7il772hw2jkf3b6/wish/2507722518     1. Brief definition paulinewong1 https://padlet.com/paulinewong1/w7il772hw2jkf3b6/wish/2507722521 Acute Respiratory Distress Syndrome 
    Inflammation throughout lungs, non - cardiogenic related as a result of acute diffuse lung injury

    Fluid moves into the alveoli affecting the surfactant layer and therefore reducing compliance.

    ARDS is a complex lung disease and involves the activation and dysregulation of multiple overlapping and interacting pathways of injury, inflammation, and coagulation, both in the lung and systemically.]]>     2023-03-08 00:28:59 UTC https://padlet.com/paulinewong1/w7il772hw2jkf3b6/wish/2507722521     2. Is it obstructive or restrictive? Why? paulinewong1 https://padlet.com/paulinewong1/w7il772hw2jkf3b6/wish/2507722522 Restrictive
    Due to decreased lung compliance as a result of bilateral infiltrates to lung
    Prevents expansion and recoil 
    Hypoventilation 
    reduces ability for body to build its own surfactant therefore reducing compliance]]>     2023-03-08 00:28:59 UTC https://padlet.com/paulinewong1/w7il772hw2jkf3b6/wish/2507722522     3. How does the condition effect lung compliance and/or airway resistance? paulinewong1 https://padlet.com/paulinewong1/w7il772hw2jkf3b6/wish/2507722523 Fluid moves into the alveoli effecting the surfactant layer and therefore reducing compliance as surfactant production is reduced this then causes the alveoli to become firm and reduce effective ventilation]]> 2023-03-08 00:28:59 UTC https://padlet.com/paulinewong1/w7il772hw2jkf3b6/wish/2507722523 4. Explain the role of V/Q mismatch in this condition. paulinewong1 https://padlet.com/paulinewong1/w7il772hw2jkf3b6/wish/2507722524 Ventilation is reduced because of increase in permeability of membrane there is fluid in alveoli causing barrier to normal exchange.
    Normal perfusion 
    V/Q ratio will be reduced 
    A-a gradient increased ]]>     2023-03-08 00:28:59 UTC https://padlet.com/paulinewong1/w7il772hw2jkf3b6/wish/2507722524     5. How is oxygenation and ventilation affected? Eg. consider O2 content, O2 delivery, alveolar ventilation paulinewong1 https://padlet.com/paulinewong1/w7il772hw2jkf3b6/wish/2507722525 Hypoventilation, hypoxemia
    Consider oxygen content PaO2 - O2 content varying based on level of ARDS, mild, moderate severe and hB   expect PaO2 to be markedly reduced so oxygen delivery would be decreased. 
    Poor ventilation at the alveolar level due to reduced compliance with fluid build up in alveoli

    ]]>     2023-03-08 00:28:59 UTC https://padlet.com/paulinewong1/w7il772hw2jkf3b6/wish/2507722525     6. What type of respiratory failure would this condition lead to? paulinewong1 https://padlet.com/paulinewong1/w7il772hw2jkf3b6/wish/2507722526 Initially present as type 1 then pt would become fatigued and retain CO2 developing hypercapnia and therefore type 2]]> 2023-03-08 00:28:59 UTC https://padlet.com/paulinewong1/w7il772hw2jkf3b6/wish/2507722526 7. What are the typical ABGs and why? paulinewong1 https://padlet.com/paulinewong1/w7il772hw2jkf3b6/wish/2507722527 high ph
    low PaO2 - hypoxic 
    Co2 low or normal

    as progresses will then develop respiratory alkalosis due to hyperventilation 
    as compensatory mechanisms.
    As surfactant reduced and lungs become firm with reduced compliance leading to retained CO2 and become a respiratory acidosis.

    ]]>     2023-03-08 00:28:59 UTC https://padlet.com/paulinewong1/w7il772hw2jkf3b6/wish/2507722527     8. What are the typical clinical manifestations/ patient assessment data? (relate these to pathophysiology concepts already described) paulinewong1 https://padlet.com/paulinewong1/w7il772hw2jkf3b6/wish/2507722528 Sudden clinical deterioration.
    Type 1 resp failure symptoms 
    diffuse bilateral opacities on chest X-ray. Chest auscultation would hear crackles then pleural friction rub. Apex to base may be affected. 
    low P/F ratio 
    Increased WOB, use of accessory muscles presenting hyperventilating to aid in relieving hypoxia, will then become hypoventilation due to reduced compliance. 
    Decreased tidal volume ]]>     2023-03-08 00:28:59 UTC https://padlet.com/paulinewong1/w7il772hw2jkf3b6/wish/2507722528     9. OPTIONAL: Important vocabulary (include list of key vocabulary referenced; if you do not know the term(s), look up and add a definition for the word(s)) paulinewong1 https://padlet.com/paulinewong1/w7il772hw2jkf3b6/wish/2507722529
    The current Definition of ARDS for Oxygenation is P/F Ratio the ff:

    300 to 200 is Mild
    200 to 100 is Moderate
    Less than 100 is Severe ARDS with PEEP ≥ 5.]]>     2023-03-08 00:28:59 UTC https://padlet.com/paulinewong1/w7il772hw2jkf3b6/wish/2507722529