Last Evaluative Activity - Genetics and Molecular Biology by Aylla Camila https://padlet.com/ayllaludi/v7r4tsayyowcuj87 Post here your infographic and the analysis you did according to the Critical Thinking questions. en-us 2021-06-20 23:44:25 UTC 2026-03-23 00:18:23 UTC hello@padlet.com Aluna: Laís Capelasso Lucas Pinheiro. PROSTATE CANCER https://padlet.com/ayllaludi/v7r4tsayyowcuj87/wish/1621759027 1 - What are the main ideas of the text? The text talks about prostate cancer, its risk factors, incidence, mortality and prevention.
2 - Why should people know about this? People should know about this to avoid the risk factors of prostate cancer and get regular checkups.
3 - What are the applications of this research? This research can be applied in other studies about prostate cancer. To study the genetic mutations, or the biomarkers for a disease, the researcher needs to understand the risk factors, ways of prevention and the incidence rates of that disease.
4 - Where can we get more information about that topic? We can get more information in the references of the text and in data platforms, such as Google Scholar, PubMed and SciELO. 
5 - When would these findings presented benefit our society? The results of a review article can benefit society when it informs and actualizes people about a problem, as we can see in this case, prostate cancer. Or when it is used as a reference to an experimental article that discovers a new drug, mutation or biomarker to help in the treatment of prostate cancer.
6 - Why is this research relevant? This research is relevant because we need to understand how cancer occurs around the world and which are its risk factors to treat the most vulnerable people.
7 - How do we see this topic in the future? In the future I imagine that the researchers will be able to establish a relationship between gene mutations and prostate cancer development. So, at this point, the identification and prevention of prostate cancer will be easier. 
8 - What is your opinion about the goals that you read? The goals of this text were to do a detailed analysis of the epidemiology of prostate cancer to understand the connection between the genetic mutations and environmental influences in the progression of this type of cancer. In my opinion, this is very important to understand the prostate cancer incidence and mortality. ]]> 2021-06-23 14:16:03 UTC https://padlet.com/ayllaludi/v7r4tsayyowcuj87/wish/1621759027 Aluno: Leonardo Adabo Cintra Unveiling a unique genetic diversity of cultivated Coffeaarabica L. in its main domestication center: Yemen https://padlet.com/ayllaludi/v7r4tsayyowcuj87/wish/1623631503
  • What are the main ideas of the text? It is an Investigation into the genetic diversity of C. arabica based on Single Sequence Repeats (SSR) molecular markers in cultivated varieties from Yemen, its domestication center. Being possible to cluster close varieties to identify their shared and singular features. 
  • Who is mostly affected by this research? Why? Not just plant improvement researchers, but every coffee producer and consumers can be benefited by this research.
  • What are the applications of this research? Knowing the genetic diversity of a plant species helps in its genetic improvement, and in improving the quality of the commodity.
  • Where can we get more information about that topic? In agronomic scientific journals. 
  • When would these findings presented benefit our society? It may take a few years for this to become a product, but the impact of information on the scientific niche is instantaneous.
  • Why is this research relevant? Because it allows the understanding of genetic variation in a commercially important crop species after the process of domestication and widely cultivation.
  • How do we see this topic in the future? This topic can generate the knowledge necessary for C. arabica cultivars to be genetically improved, reducing the need for pesticides and improving the quality of the coffee beverage.
  • What is your opinion about the goals that you read? The study is so sool, it precisely grouped the coffee varieties into five clusters according to their genetic characteristics and their origin, using a very interesting genomic methodology from a phylogenetic point of view. Highlighting a cluster unique to Yemen region. 

    • ]]>     2021-06-24 13:54:36 UTC https://padlet.com/ayllaludi/v7r4tsayyowcuj87/wish/1623631503     Aluna: Larissa C B de Oliveira THE ROLE OF FLAVONOIDS IN THE TREATMENT OF CANCER CELLS https://padlet.com/ayllaludi/v7r4tsayyowcuj87/wish/1623673869 1- What are the main ideas of the text?
    The main idea of the text is the role of phytochemicals against cancer. During text development, some topics are highlighted like types of phytochemicals as well as their structure and mechanisms of action of these compounds on cancer.
    2- Who is mostly affected by this research? Why?
    Currently, cancer is a huge health problem worldwide, so in the end everyone is affected by results of this research, but more specifically, cancer researchers and doctors are firstly affected by this text.
    3- What are the applications of this research?
    This research has many potential applications in fact the main one of it is cancer treatment.
    4- Where can we get more information about that topic?
    We can get more information about that topic from many sources, for example journals of cancer treatment, phytochemicals and websites that discuss the same subject.
    5- When would these findings presented benefit our society?
    These discoveries have already brought benefits to our society because many of our existing drugs are derived from phytochemicals or are developed using their chemical structure as a basis. However, despite this, there are so many unexplored phytochemicals to test on cancer cells.
    6- Why is this research relevant?
    This research is relevant because many people are dying of cancer around the world and because current treatments have extensive side effects.
    7- How do we see this topic in the future?
    I see this topic highly developed in the future providing new ways to treat cancer without side effects.
    8- What is your opinion about the goals that you read?
    The goals are totally approachable besides they are strongly necessary to our society. Definitely, phytochemicals can be used in cancer therapies.]]>     2021-06-24 14:17:47 UTC https://padlet.com/ayllaludi/v7r4tsayyowcuj87/wish/1623673869     Aluno: Matheus Mertz Ribeiro. PHYTOCHEMICALS 1. What are the main ideas of the text? A study that shows the effect of phytochemicals such as curcumin, resveratrol, folate, lycopene, beta carotene and allicin. These compounds have positive effects on human health, besides providing great results in the fight against comorbidities, especially cancer. 2- Who is mostly affected by this research? Why? We (ordinary people). Due to the fact that these studies prove that molecules present in food can provide a better condition of life, reducing the risk of disease proliferation, and that a healthier lifestyle can contribute positively to this. 3- What are the applications of this research? It shows some main foods that can be present in our diet (because they are excellent for health), or even the development of natural therapies and remedies obtained from these molecules. 4- Where can we get more information about that topic? In other articles, websites, documentaries, etc... 5- When would these findings presented benefit our society? In the not too distant future, some molecules are already well known, we just need to introduce these foods in our diet. However, there are still many other molecules to be studied and discovered. Scientists cannot give up, despite the lack of financial resources and the disbelief of some people in society. 6- Why is this research relevant? The search for new antioxidant, anticarcionogenic and anti-inflammatory molecules is becoming more and more constant. Natural resources (vegetables and fruits) present a great quantity of these compounds and present a great potential to combat diseases. 7- How do we see this topic in the future? I hope very well elucidated, however it is a work that requires a lot of dedication and time. But in the future many of the compounds will come from plants, because we are entering a "green" era, with a focus on BIO, in other words, a focus on nature, by the use of more natural compounds or compounds that do not cause so much harm to the environment, people/companies increasingly opting for more ecological options. 8- What is your opinion about the goals that you read? My opinion is that very little is known about the great potential of plants, as we have been using them for hundreds of years, such as in teas and cooking. And that a healthy diet, combined with an active lifestyle (physical activity), can provide a very good condition of life in relation to not developing diseases (such as cancer). And hopefully in a few years science will have discovered new molecules that provide several positive effects for our health. https://padlet.com/ayllaludi/v7r4tsayyowcuj87/wish/1624155992 2021-06-24 19:40:31 UTC https://padlet.com/ayllaludi/v7r4tsayyowcuj87/wish/1624155992 Matheus Felipe da Silva https://padlet.com/ayllaludi/v7r4tsayyowcuj87/wish/1627233245 What are the main ideas of the text?
    The main idea of this research was to describe the pharmacological effects and mechanisms of action of a phytochemical known as diosgenin. 
    Who is mostly affected by this research? Why?
    This research can affect patients with chronic diseases known for high rates of morbidity and mortality such as cancer, neuropathies, heart disease and diabetes. Preclinical studies demonstrate that diosgenin has anti-diabetic, neuroprotective, anti-inflammatory, antioxidant, immunoregulatory and anti-cancer activities. 
    What are the applications of this research?
    This research enables the production of new studies through the generation of relevant information about the effects of diosgenin in different pathological conditions. 
    Where can we get more information about that topic?
    The PubMed database and academic google can be used to search for more information about diosgenin. 
    When would these findings presented benefit our society?
    Para que a diosgenina passe a categoria de fármaco e beneficie a sociedade é necessário o desenvolvimento de estudos clínicos.  
    Why is this research relevant?
    Diosgenin is a promising phytochemical for the treatment of complex diseases, as it can act on different molecular targets. Thus, this study may help to elucidate the mechanisms of action of diosgenin. 
    How do we see this topic in the future?
    Diosgenin is a very promising chemical compound to become a drug in the future, as many clinical studies have already elucidated many of its pharmacological properties and its molecular targets. 
    What is your opinion about the goals that you read?
    The established objectives were achieved through a review of recent and relevant literature of the main findings of the pharmacological effects of diosgenin. ]]>     2021-06-27 20:11:47 UTC https://padlet.com/ayllaludi/v7r4tsayyowcuj87/wish/1627233245     Aluna: Talita Pijus Ponce Genetics of coffee quality talitapijusponce https://padlet.com/ayllaludi/v7r4tsayyowcuj87/wish/1628478597 1. What are the main ideas of the text?
    The quality of the coffee has been considered the main selection criterion in the improvement of this crop. The wide variation within and between coffee species is mainly related to biochemical characters related to quality (caffeine, sugars, chlorogenic acids, lipids)
    2. Who is mostly affected by this research? Why?
    First of all, the consumer, who will result in quality coffees for consumption, this is the final objective of the entire research. It will also be of great importance for improvement programs, that is, who develops the research and also for industries that take research to the consumer.
    3. What are the applications of this research?
    Genetic factors involved in controlling variation of the quality of the coffee. Regarding the complexity of this feature, the different types of quality are presented. Ways to improve these characters related to quality in the cultivated species Coffea arabica and Coffea canephora are discussed, as well as the challenges species-specific.
    4. Where can we get more information about that topic?
    Scientific articles, news articles, newsletters, books, cultivar dissemination events launched by companies.
    5. When would these findings presented benefit our society?
    the results of these studies on coffee quality have been presented to society for a long time, and every year we have important new information being discovered by the studies.
    6. Why is this research relevant?
    This research is relevant because, in addition to the quality of coffee as a beverage (taste, aroma), in terms of chemical compounds present in coffee beans, several of them are known to have health consequences. Despite its positive effect on alertness, caffeine also has some possible implications for diseases such as hypercholesterol and cancer. Coffee also contains chlorogenic acids, melanoidins and other unknown substances that are identified as strong antioxidants. Coffea species-specific diterpenes (Cafestol and Kahweol) have also been shown to have some hypercholesterol properties associated with possible antioxidant properties. In short, despite the knowledge acquired about some components in terms of health consequences, very little is known about the other constituents that make up 98% of roasted coffee beans.
    7. How do we see this topic in the future?
    I see this topic being very well used and with many others in this line of research being developed, such as in the genetic improvement of the coffee crop, in researching chemical compounds that can affect the health of the consumer, combining all the improvements in the quality of the coffee
    8. What is your opinion about the goals that you read?
    I found the study very interesting and necessary because there is great variation within and between coffee species, especially for biochemical compounds related to quality (caffeine, sugars, chlorogenic acids, lipids). Ways of improving the quality characters for the cultivated species, Coffea arabica and Coffea canephora, are discussed, with specific challenges for each species.]]>     2021-06-28 14:32:55 UTC https://padlet.com/ayllaludi/v7r4tsayyowcuj87/wish/1628478597     Aluno: Matheus de Moura Silva matheusmourasilva6 https://padlet.com/ayllaludi/v7r4tsayyowcuj87/wish/1628519505 1.What are the main ideas of the text?

    R. The article talks about the importance of botanical gardens in the conservation of plants around the world. The article says that botanical gardens are no longer something exclusive to kings and queens, and nowadays they have a study function aimed at conservation. Another important aspect that the article touches on is the importance of making the local population aware of how important the preservation of the different species of plants is for the maintenance of the diversity of species.

    2.Who is mostly affected by this research? Why?

    R. The most affected are the plants. The article shows that botanical gardens, especially those found in hotspot environments, play a big role in preserving species in this region. 

    3.How can the population help the botanical gardens?

    R. People can help by donating money or even donating equipment that helps in the maintenance of the gardens. They can also help by donating land for the expansion of the botanical gardens, also by participating in projects that the botanical gardens have such as reforestation projects  
     
    4. Where can we get more information about that topic?

    R. We can get more information by going to the botanical gardens and asking the people who work there about their importance. We can also look for other (scientific) works that show the importance of the botanical gardens in plant preservation.

    5. When would these findings presented benefit our society?
    R. The benefits are the preservation of plants, the discovery of new remedies from medicinal plants.

    6 .Why is this research relevant?

    R. Because nowadays the florest are even more threatened environments, and botanical gardens are starting to become protection environments for the maintenance of plant diversity. The article shows us this by presenting the role that botanical gardens have for the maintenance of biodiversity and awareness projects with the local population.  

    7.How do we see this topic in the future?

    R. With the growth of the population and the increased demand for food production, regions that are native forests are being deforested and end up becoming areas for agriculture. Many times, these areas are opened up irregularly, which results in a loss of biodiversity. For plants, botanical gardens are used as biodiversity protection banks, preventing certain groups of plants from becoming extinct.  

    8. What is your opinion about the goals that you read?

    R. I think the insight that the article gave me about botanical gardens is very valuable. I had a vision that the botanical gardens were just a place to exhibit plants but the point that the article demonstrates is that the botanical gardens are not just an exhibit environment, they are also a study environment for these plants as well as  a protection environment for many species that are endangered. 

    ]]>     2021-06-28 14:59:19 UTC https://padlet.com/ayllaludi/v7r4tsayyowcuj87/wish/1628519505     Aluna: Angelita Garbossi Silva https://padlet.com/ayllaludi/v7r4tsayyowcuj87/wish/1628583791 CASE STUDY: COFFEE WILD SPECIES AND CULTIVARS

    1. What are the main ideas of the text?
    Coffea arabica (Arabica) and Coffea canephora (Robusta) are the two main cultivated species of Coffea. Arabica coffee represents 60-70% of the world coffee market. Robusta plants are more resistant to disease and parasites and have 50-60% more caffeine compared to Arabica. There are 124 described Coffea species, most of which are native to Africa. In Ethiopia, wild C. arabica grows as an understory shrub and exhibits wide genotypic and phenotypic variability. The wild species are genetically distinct from cultivars Typica and Bourbon, which are derived from Coffea arabica, and have been frequently used in breeding programs because they are resistant to some diseases and pests that affect the coffee tree.
    2. Who is mostly affected by this research? Why?
     This study will certainly serve as a basis for researchers in the field of coffee genetic improvement, but it is also interesting for the general public, especially those who enjoy our dear coffee.
    3. What are the applications of this research?
    For genetic improvement, it is interesting to cross species that have characteristics of interest, for example to obtain a cultivar that is superior, it could be resistant to diseases and with good coffee drink quality. 
    4. Where can we get more information about that topic?
    Scientific articles, books, research articles, newsletters...
    5. When would these findings presented benefit our society?
    Brazil is the world's largest coffee producer. Since its arrival in the country in 1727, coffee has been the greatest generator of wealth and the most important product in national history. And since then, research has been carried out to advance agronomic characteristics of interest.
    6. Why is this research relevant?
    Because research involving the genetic improvement of coffee has its importance, as it is a crop of great economic influence, in addition to being widely consumed worldwide.
    7. How do we see this topic in the future?
    The search for quality coffee drink and disease resistance has been the target of many improvement programs, so finding cultivars with such characteristics will be a great advance for society, and we hope it happens soon.
    8. What is your opinion about the goals that you read?
    In addition to the characteristics mentioned above, sustainability is an issue of great importance. The genetic variability of coffee is part of this, because if we cross species to improve characteristics, we are enriching the genetic data. The study showed us that wild coffee species have desirable characteristics that can be incorporated into Arabica and Robusta coffee cultivars. In addition to observing that if any species does not have genetic variability such as C. arabica, there are other species that have a rich source of diversity, and this allows us, through research, to merge such species and increase the precious genetic diversity of the coffee tree.


    ]]>     2021-06-28 15:43:21 UTC https://padlet.com/ayllaludi/v7r4tsayyowcuj87/wish/1628583791     Milene Roldão de Souza https://padlet.com/ayllaludi/v7r4tsayyowcuj87/wish/1628660525 1-What are the main ideas of the text?
    The main idea of the text is to make an update about bladder cancer. Especially the epidemiology of bladder cancer.

    2-Who is mostly affected by this research? Why?
    The entire population, because bladder cancer is an important health problem and knowing about the causes, therapeutics and risks can help to prevent this disease. Although this cancer happens in both sexs, men  are mostly affected by bladder cancer, which means that men are mostly affected by this research.

    3-What are the applications of this research?
    This research has clinicals applications. Such as help to identify what kind of cancer forms that the patient has and how the best option to treat this one.  This research is very useful to show how we can prevent this type of cancer, also who is more likely to developpement bladder cancer.

    4-Where can we get more information about that topic?
    Official sites about cancer, books and scientific magazines

    5-When would these findings presented benefit our society?
    Actually, the information that the article brings is acknowledged and the authors made an update about this topic. The epidemiologic informations are used in a clinical routine

    6-Why should people know about this?
    People must know this to make good choices and avoid major risk factors such as tobacco and occupational or environmental exposure

    7-How do we see this topic in the future?
    As a topic with many discoveries and resources that can help people, for example, with new non-invasive biomarkers that can identify early cancer, then make better the treatment. Also, I hope that topic i'll be more comented than nowadays.

    8-What is your opinion about the goals that you read?
    Articles like these are very important in the cancer scenario. They help scientists and doctors stay up to date and make better choices such as what type of cancer the patient has and what is the best option of treatment for this patient. As well, these articles show new screening techniques, where this cancer is most frequently and who is more affected.


    ]]>     2021-06-28 16:40:06 UTC https://padlet.com/ayllaludi/v7r4tsayyowcuj87/wish/1628660525     Aluna: Letícia Maria Parteka - Polyploidization of the Arabidopsis thaliana tapetum leticiamariaparteka https://padlet.com/ayllaludi/v7r4tsayyowcuj87/wish/1628814038 What are the main ideas in the text?
    The main ideas of the text are to analyze the degree of polyploidization of the Arabidopsis thaliana tapetum comparing two plants with different ploidy degree and in what this difference interferes, through a methodological proposal already used in other analyses, but never tested to analyze the degree of polyploidization of these cells.
    Who is most affected by this research? Because?
    Researchers in the fields of botany, genetics, cytogenetics, cell biology and plant reproductive biology are the most affected by this research, as it is a specific subject related to these areas of study.
    What are the applications of this research?
    The application is related to approaching a methodology not yet studied to obtain interesting and more robust results on this subject, in order to be able to analyze how variation in the ploidy of tapetum cells interferes or helps in the development of the pollen grain.
    Where can we get more information on this topic?
    In articles related to pollen grain development and plant reproduction we can get more information on this topic.
    When would these presented discoveries benefit our society?
    These discoveries are the results of researches called base, in which these same results, together with other researches, result in the understanding of the pollen grain formation mechanism and the pollen viability, which later influences the species reproduction.
    Why is this research relevant?
    This research is relevant to the field that studies plant reproduction, bringing a different approach to an existing method and relevant results in a study model plant.
    How do we see this topic in the future?
    This topic will be addressed in the future in different analyses, leading to an understanding of which genes are related to this increase in ploidy and how this mechanism of increasing ploidy works in different species and how this mechanism influences the development of the pollen grain.
    What is your opinion about the goals you read?
    In my opinion, this is an interesting subject for the area, which clarified some basic and necessary points to be able to deepen the relationship that the tapetum tissue has in the formation of the pollen grain.

    ]]>     2021-06-28 18:49:06 UTC https://padlet.com/ayllaludi/v7r4tsayyowcuj87/wish/1628814038     https://padlet.com/ayllaludi/v7r4tsayyowcuj87/wish/1649844281 2021-07-14 20:17:59 UTC https://padlet.com/ayllaludi/v7r4tsayyowcuj87/wish/1649844281