https://padlet.com/kathryn_gable_342/uldfnz0b8yay en-us 2019-10-10 20:40:44 UTC 2023-05-16 16:07:57 UTC hello@padlet.com https://padlet.net/icons/png/1f604.png ryan_mcnair_122 https://padlet.com/kathryn_gable_342/uldfnz0b8yay/wish/396422376 2019-10-10 20:45:11 UTC https://padlet.com/kathryn_gable_342/uldfnz0b8yay/wish/396422376 ryan_mcnair_122 https://padlet.com/kathryn_gable_342/uldfnz0b8yay/wish/396422596 2019-10-10 20:45:33 UTC https://padlet.com/kathryn_gable_342/uldfnz0b8yay/wish/396422596 ryan_mcnair_122 https://padlet.com/kathryn_gable_342/uldfnz0b8yay/wish/396422900 Graves' Disease- Hypersecretion

Graves' disease is caused by a malfunction in the immune system, although the exact reason why this happens is still unknown. The body produces an antibody to one part of the cells in the thyroid gland. The immune system makes an antibody called thyroid-stimulating immunoglobulin (TSI) that attaches to thyroid cells. TSI acts like thyroid-stimulating hormone (TSH), a hormone made in the pituitary gland that tells the thyroid how much thyroid hormone to make. This causes the thyroid gland to be stimulated by both the pituitary gland hormone and antibodies which makes the thyroid overproduce thyroid hormone.]]> 2019-10-10 20:46:28 UTC https://padlet.com/kathryn_gable_342/uldfnz0b8yay/wish/396422900 ryan_mcnair_122 https://padlet.com/kathryn_gable_342/uldfnz0b8yay/wish/396423284 2019-10-10 20:47:35 UTC https://padlet.com/kathryn_gable_342/uldfnz0b8yay/wish/396423284 ryan_mcnair_122 https://padlet.com/kathryn_gable_342/uldfnz0b8yay/wish/396423415 Cretinism]]> 2019-10-10 20:48:00 UTC https://padlet.com/kathryn_gable_342/uldfnz0b8yay/wish/396423415 ryan_mcnair_122 https://padlet.com/kathryn_gable_342/uldfnz0b8yay/wish/396423606 Grave's Disease

]]> 2019-10-10 20:48:31 UTC https://padlet.com/kathryn_gable_342/uldfnz0b8yay/wish/396423606 ryan_mcnair_122 https://padlet.com/kathryn_gable_342/uldfnz0b8yay/wish/396423964 2019-10-10 20:49:31 UTC https://padlet.com/kathryn_gable_342/uldfnz0b8yay/wish/396423964 ryan_mcnair_122 https://padlet.com/kathryn_gable_342/uldfnz0b8yay/wish/396428966 Cretinism is untreated congenital hypothyroidism]]> 2019-10-10 21:04:14 UTC https://padlet.com/kathryn_gable_342/uldfnz0b8yay/wish/396428966 ryan_mcnair_122 https://padlet.com/kathryn_gable_342/uldfnz0b8yay/wish/398701990 Iron deficiency
Prenatal trauma
Underactive pituitary gland
Genetic predisposition]]> 2019-10-16 19:55:59 UTC https://padlet.com/kathryn_gable_342/uldfnz0b8yay/wish/398701990 kathryn_gable_342 https://padlet.com/kathryn_gable_342/uldfnz0b8yay/wish/398703417 Graves' disease is an autoimmune disorder that results in hyperthyroidism]]> 2019-10-16 19:59:27 UTC https://padlet.com/kathryn_gable_342/uldfnz0b8yay/wish/398703417 ryan_mcnair_122 https://padlet.com/kathryn_gable_342/uldfnz0b8yay/wish/398704262 Cretinism can result in severe mental and physical retardation if not treated before three to fourweeks (the severity is due to the importance of the first six months of growth).]]> 2019-10-16 20:01:31 UTC https://padlet.com/kathryn_gable_342/uldfnz0b8yay/wish/398704262 ryan_mcnair_122 https://padlet.com/kathryn_gable_342/uldfnz0b8yay/wish/398705924 - Hyposecretion]]> 2019-10-16 20:05:24 UTC https://padlet.com/kathryn_gable_342/uldfnz0b8yay/wish/398705924 ryan_mcnair_122 https://padlet.com/kathryn_gable_342/uldfnz0b8yay/wish/398706132 - Hypersecretion]]> 2019-10-16 20:05:52 UTC https://padlet.com/kathryn_gable_342/uldfnz0b8yay/wish/398706132 ryan_mcnair_122 https://padlet.com/kathryn_gable_342/uldfnz0b8yay/wish/398706320 Routine prenatal and postnatal testing using the Guthrie Test, and blood TSH tests ]]> 2019-10-16 20:06:17 UTC https://padlet.com/kathryn_gable_342/uldfnz0b8yay/wish/398706320 ryan_mcnair_122 https://padlet.com/kathryn_gable_342/uldfnz0b8yay/wish/398708146 Early diagnosis is important- cretinism can be prevent if T4 is pushed within the first month. The preferred treatment is replacement therapy to raise T4 and T3 levels.]]> 2019-10-16 20:10:53 UTC https://padlet.com/kathryn_gable_342/uldfnz0b8yay/wish/398708146 ryan_mcnair_122 https://padlet.com/kathryn_gable_342/uldfnz0b8yay/wish/398710582 The thyroid gland produces Thyroxine (T4) and Triiodothyronine (T3), and is the major metabolic hormone. It controls the rate of oxidation of glucose to supply body heat and chemical energy, and is needed for tissue growth and development.]]> 2019-10-16 20:16:09 UTC https://padlet.com/kathryn_gable_342/uldfnz0b8yay/wish/398710582 ryan_mcnair_122 https://padlet.com/kathryn_gable_342/uldfnz0b8yay/wish/398711460 The thyroid gland is found at the base of the throat, and consists of two lobes and a connecting isthmus. It's also called the "butterfly" gland, and houses the parathyroid glands on its posterior. ]]> 2019-10-16 20:18:04 UTC https://padlet.com/kathryn_gable_342/uldfnz0b8yay/wish/398711460 ryan_mcnair_122 https://padlet.com/kathryn_gable_342/uldfnz0b8yay/wish/398712598 2019-10-16 20:20:41 UTC https://padlet.com/kathryn_gable_342/uldfnz0b8yay/wish/398712598 ryan_mcnair_122 https://padlet.com/kathryn_gable_342/uldfnz0b8yay/wish/398713056 T4 is secreted by thyroid follicles. It plays a central role in digestion, heart and muscle function, brain development, and maintenance of bones. ]]> 2019-10-16 20:21:48 UTC https://padlet.com/kathryn_gable_342/uldfnz0b8yay/wish/398713056 ryan_mcnair_122 https://padlet.com/kathryn_gable_342/uldfnz0b8yay/wish/398715385 Conversion of T4 at target tissues. T3 regulates body temperature, metabolism, and heart rate. ]]> 2019-10-16 20:26:59 UTC https://padlet.com/kathryn_gable_342/uldfnz0b8yay/wish/398715385 ryan_mcnair_122 https://padlet.com/kathryn_gable_342/uldfnz0b8yay/wish/398716285 2019-10-16 20:29:15 UTC https://padlet.com/kathryn_gable_342/uldfnz0b8yay/wish/398716285 ryan_mcnair_122 https://padlet.com/kathryn_gable_342/uldfnz0b8yay/wish/398723554 A combination of genes and outside triggers (like a virus)]]> 2019-10-16 20:49:32 UTC https://padlet.com/kathryn_gable_342/uldfnz0b8yay/wish/398723554 ryan_mcnair_122 https://padlet.com/kathryn_gable_342/uldfnz0b8yay/wish/398725856 The hypothalamus releases TRH- thyrotropin releasing hormone, which in turn tells the anterior pituitary gland to release TSH- thyroid stimulating hormone. TSH tells the thyroid to produce T4 and T3. ]]> 2019-10-16 20:56:50 UTC https://padlet.com/kathryn_gable_342/uldfnz0b8yay/wish/398725856 ryan_mcnair_122 https://padlet.com/kathryn_gable_342/uldfnz0b8yay/wish/398727275 2019-10-16 21:00:58 UTC https://padlet.com/kathryn_gable_342/uldfnz0b8yay/wish/398727275 ryan_mcnair_122 https://padlet.com/kathryn_gable_342/uldfnz0b8yay/wish/398728210 2019-10-16 21:02:18 UTC https://padlet.com/kathryn_gable_342/uldfnz0b8yay/wish/398728210 ryan_mcnair_122 https://padlet.com/kathryn_gable_342/uldfnz0b8yay/wish/398728756 2019-10-16 21:03:51 UTC https://padlet.com/kathryn_gable_342/uldfnz0b8yay/wish/398728756 ryan_mcnair_122 https://padlet.com/kathryn_gable_342/uldfnz0b8yay/wish/398729293 Can result in Graves' opthalmopathy and Graves' dermopathy. Increased irritability, heat sensitivity, unchecked weight loss, and arrhythmia. Thyrotoxix crisis' are a life-threatening condition possible with severe hyperthyroidism.]]> 2019-10-16 21:05:27 UTC https://padlet.com/kathryn_gable_342/uldfnz0b8yay/wish/398729293 ryan_mcnair_122 https://padlet.com/kathryn_gable_342/uldfnz0b8yay/wish/399725229 Physical exams (noticing abnormal BMI or thyroid size), blood tests (testing for T4 and T3 levels), ultrasounds, and radioactive iodine uptake (RAIU) tests.]]> 2019-10-18 19:56:44 UTC https://padlet.com/kathryn_gable_342/uldfnz0b8yay/wish/399725229 ryan_mcnair_122 https://padlet.com/kathryn_gable_342/uldfnz0b8yay/wish/399726362 The treatment goals for Graves' is to inhibit thyroid production and block the effects of hypersecretion.

This is done in a myriad of ways, including; anti-thyroid medication, iodine therapy, beta-blockers (for symptoms), and even surgery (in severe cases)]]> 2019-10-18 20:00:50 UTC https://padlet.com/kathryn_gable_342/uldfnz0b8yay/wish/399726362 ryan_mcnair_122 https://padlet.com/kathryn_gable_342/uldfnz0b8yay/wish/399728006 Cretinism- Hyposecretion

During the first few months of pregnancy, the developing baby depends solely on the mother for its thyroid hormone supply, which is essential for normal growth and brain development. In a normal pregnancy, the child would being to develop it's own T3. When the child has cretinism, it doesn't produce its T3, so when the mother stops, the child is left with a hyposecreting thyroid. This causes cretinism or related hypothyroid diseases. ]]> 2019-10-18 20:06:30 UTC https://padlet.com/kathryn_gable_342/uldfnz0b8yay/wish/399728006 kathryn_gable_342 https://padlet.com/kathryn_gable_342/uldfnz0b8yay/wish/399729503 2019-10-18 20:11:45 UTC https://padlet.com/kathryn_gable_342/uldfnz0b8yay/wish/399729503 ryan_mcnair_122 https://padlet.com/kathryn_gable_342/uldfnz0b8yay/wish/399730853 2019-10-18 20:17:07 UTC https://padlet.com/kathryn_gable_342/uldfnz0b8yay/wish/399730853 kathryn_gable_342 https://padlet.com/kathryn_gable_342/uldfnz0b8yay/wish/399735681 2019-10-18 20:35:28 UTC https://padlet.com/kathryn_gable_342/uldfnz0b8yay/wish/399735681