Cell Communication: Alopecia by Cassi Deckard https://padlet.com/scdeckard/tq4xo9cyojlt By Cassi, Jessica, Ashley en-us 2017-10-20 00:59:46 UTC 2023-01-23 23:25:47 UTC hello@padlet.com What is it? scdeckard https://padlet.com/scdeckard/tq4xo9cyojlt/wish/198911630 Scientifically known as Allopeica aerate, this cell signaling disease is a common autoimmune skin disease, causing hair loss on the scalp, face and sometimes on other areas of the body. The immune system mistakenly attacks hair follicles which causes the hair loss. Usually it first appears during a person's childhood.]]> 2017-10-20 01:01:38 UTC https://padlet.com/scdeckard/tq4xo9cyojlt/wish/198911630 Symptoms scdeckard https://padlet.com/scdeckard/tq4xo9cyojlt/wish/198911665 -Bald spots
-Pain or tingling at sights of hair loss
-"Exclamation point" hairs]]> 2017-10-20 01:01:52 UTC https://padlet.com/scdeckard/tq4xo9cyojlt/wish/198911665 Cell Signaling Pathway scdeckard https://padlet.com/scdeckard/tq4xo9cyojlt/wish/198912510 The cell signaling pathway involved with Alopecia is known as the 'Androgen Receptor Pathway.' 

]]> 2017-10-20 01:07:40 UTC https://padlet.com/scdeckard/tq4xo9cyojlt/wish/198912510 Correct Mechanism scdeckard https://padlet.com/scdeckard/tq4xo9cyojlt/wish/198913200 In an Androgen Receptor Signaling Pathway, testosterone works with 5 alpha-reductase to bind to DHT in hair follicles. The 5 alpha reductase binds with receptors in DHT, which then binds to the androgen receptor forming an androgen-receptor complex.

This complex binds to DNA inside the nucleus, which regulates responsive genes, like hair growth in this case.

]]> 2017-10-20 01:10:54 UTC https://padlet.com/scdeckard/tq4xo9cyojlt/wish/198913200 Incorrect Mechanism scdeckard https://padlet.com/scdeckard/tq4xo9cyojlt/wish/198915162 Your immune system acts on its own and T Cell lymphocytes bundle up and attack hair follicles causing the follicle to detach from the bloodstream making hair no longer capable to grow.
Some AR's get destroyed, so there aren't any receptors enabling hair growth.]]> 2017-10-20 01:22:59 UTC https://padlet.com/scdeckard/tq4xo9cyojlt/wish/198915162 Current Direction of Research scdeckard https://padlet.com/scdeckard/tq4xo9cyojlt/wish/198917057 There is no cure for Alopecia but there are many medications that can aid in the restoration of hair.

The National Alopecia Foundation (NAAF) is currently researching in the cure for Alopecia.

Dermatologists, Pathologists and Geneticists work together to look at the overall genetic make-up of the body, especially the cells that play a role in Alopecia and the connection of the cellular receptors in hair growth.]]> 2017-10-20 01:38:08 UTC https://padlet.com/scdeckard/tq4xo9cyojlt/wish/198917057 Androgen Receptor Pathway scdeckard https://padlet.com/scdeckard/tq4xo9cyojlt/wish/198917635 2017-10-20 01:43:29 UTC https://padlet.com/scdeckard/tq4xo9cyojlt/wish/198917635 scdeckard https://padlet.com/scdeckard/tq4xo9cyojlt/wish/198918300 2017-10-20 01:49:20 UTC https://padlet.com/scdeckard/tq4xo9cyojlt/wish/198918300 Location of the affected gene scdeckard https://padlet.com/scdeckard/tq4xo9cyojlt/wish/198918496 2017-10-20 01:51:08 UTC https://padlet.com/scdeckard/tq4xo9cyojlt/wish/198918496 scdeckard https://padlet.com/scdeckard/tq4xo9cyojlt/wish/198918976 2017-10-20 01:55:44 UTC https://padlet.com/scdeckard/tq4xo9cyojlt/wish/198918976 https://padlet.com/scdeckard/tq4xo9cyojlt/wish/427804350 2020-01-06 04:24:14 UTC https://padlet.com/scdeckard/tq4xo9cyojlt/wish/427804350