NUR140 Chemotherapy & Anti-inflammatory Presentation by https://padlet.com/venanzio_beth/140chemotherapyantiinflammatory Made with a stroke of good luck by: Markie Maraugha, Robyn Puhalla, Lauren Hordubay & Beth Venanzio en-us 2018-08-22 20:44:30 UTC 2024-05-29 08:35:30 UTC hello@padlet.com https://padlet-assets.s3.amazonaws.com/icons/Soccerball.png [7] Chapter 14 - NCLEX Question venanzio_beth https://padlet.com/venanzio_beth/140chemotherapyantiinflammatory/wish/274712790 A nurse is providing instructions to a client receiving an antineoplastic medication.  When implementing the plan, the nurse should tell the client to:
A. Drink beverages containing alcohol in moderate amount during the evening.
B. Eat high fiber rich foods.
C. Take aspirin as needed for headaches
D. Consult with health care providers before receiving immunizations.]]> 2018-08-22 20:59:05 UTC https://padlet.com/venanzio_beth/140chemotherapyantiinflammatory/wish/274712790 [1] - Chapter 14 - Introduction venanzio_beth https://padlet.com/venanzio_beth/140chemotherapyantiinflammatory/wish/274714263 Antineoplastic Agents - drugs used in cancer chemotherapy
What is chemotherapy? - most people think of fighting cancer, however only one branch of chemotherapy actually involves drugs that destroy human cells. 
What is cancer? - starts with one abnormal cell that divides and passes on the abnormalities to it's daughter cells and continues to grow.  The antineoplastic agents target the abnormal cells, however normal cells are also affected.

Antioplastic agents-  there are various types of these agents, which we will discuss today.  These specific drugs fight neoplasms (or cancers).  The unfortunate part of these drugs is they also effect normal healthy cells which can lead to debilitating side effects and a even further weakened immune system. They can have toxic effects on sperm and ova leading to decreased fertility and can be dangerous to a developing fetus.
These drugs tend to attack any rapidly growing cells, for example, hair follicles leading to hair loss in patients, GI tract leading to nausea and vomiting (which is also caused from cell death circulating in the bloodstream)
Much research is being done to create cancer fighting therapy that attacks enzymes that effect only the damaged cells...one of them we will discuss today is imantinib, which is in the category of the protein kinase inhibitor. 

In some cases, when the cancer is too big to be destroyed, the agents are used for palliative care to shrink the tumor and to alleviated some signs and symptoms of the cancer (decrease pain and increase functionality for the patient)



]]> 2018-08-22 21:08:55 UTC https://padlet.com/venanzio_beth/140chemotherapyantiinflammatory/wish/274714263 [5] - Keytruda venanzio_beth https://padlet.com/venanzio_beth/140chemotherapyantiinflammatory/wish/275220978 2018-08-24 17:51:18 UTC https://padlet.com/venanzio_beth/140chemotherapyantiinflammatory/wish/275220978 [2] - Chapter 16 - Introduction robynp12 https://padlet.com/venanzio_beth/140chemotherapyantiinflammatory/wish/275657043 Anti-inflammatory, Antiarthritis, and Related Agents
What is Inflammatory Response? - designed to protect the body from injury and pathogens.  It can be chronic -fever, aches, pains and lethargy are all caused by inflammation.

Anti-Inflammatory Drugs - Several types of drugs are used as anti-inflammatory agents. We will only be discussing drugs that have a direct effect on the inflammatory response: salicylates - aspirin; nonsteroidal anti-inflammatory drugs (NSAID's) - ibuprofen; related agents - acetaminophen; and anti arthritis drugs. 
Because these drugs are OTC abuse and over dosing are a concern.
Salicylates - (aspirin in the case of our presentation) are antipyretic (anti fever), and analgesic (pain blocking) non prescription and not toxic line of drugs.
NSAID"s - (ibuprofen) have anti inflammatory, analgesic effects without the adverse effects of corticosteroids
Related Drugs - (acetaminophen) have antipyretic effects but not as strong anti inflammatory effects as salicylates or NSAID's.  
Anti arthritis - 2 types: gold compounds that is used in specific patients with rheumatoid arthritis who don't respond to the usual anti inflammatory therapies. For those who do respond well to anti inflammatory therapies there specific drugs used to block inflammation and tissue damage often found with rheumatoid arthritis. ]]> 2018-08-27 18:49:59 UTC https://padlet.com/venanzio_beth/140chemotherapyantiinflammatory/wish/275657043 [8] - Chapter 16 - NCLEX Question robynp12 https://padlet.com/venanzio_beth/140chemotherapyantiinflammatory/wish/275685407 The nurse is teaching a client about taking aspirin.  Which of the following points are important for the nurse to include in patient teaching?  
A.  advising the client to avoid alcohol while taking aspirin.
B.  instructing the client to take aspirin before meals on an empty stomach
C.  instructing the client to inform the dentist of aspirin dosage before any dental work
D.  instructing the client to inform the surgeon of aspirin dosage before any surgery
E.  suggesting that aspirin may be given to children for fly symptoms]]> 2018-08-27 20:14:40 UTC https://padlet.com/venanzio_beth/140chemotherapyantiinflammatory/wish/275685407 [9] - Top 10 Best-Selling Cancer Drugs, Q1–Q3 2017 venanzio_beth https://padlet.com/venanzio_beth/140chemotherapyantiinflammatory/wish/275713371 2018-08-27 22:59:07 UTC https://padlet.com/venanzio_beth/140chemotherapyantiinflammatory/wish/275713371 [3] - Learning Drug Names markiemaraugha https://padlet.com/venanzio_beth/140chemotherapyantiinflammatory/wish/276027557 2018-08-28 19:35:07 UTC https://padlet.com/venanzio_beth/140chemotherapyantiinflammatory/wish/276027557 [4] - Evidence Based Article markiemaraugha https://padlet.com/venanzio_beth/140chemotherapyantiinflammatory/wish/276029970 https://www.breastcancer.org/treatment/hormonal/serms/tamoxifen]]> 2018-08-28 19:42:37 UTC https://padlet.com/venanzio_beth/140chemotherapyantiinflammatory/wish/276029970 Chapter 14 Medications venanzio_beth https://padlet.com/venanzio_beth/140chemotherapyantiinflammatory/wish/276051640 2018-08-28 21:13:53 UTC https://padlet.com/venanzio_beth/140chemotherapyantiinflammatory/wish/276051640 Chapter 16 Medications venanzio_beth https://padlet.com/venanzio_beth/140chemotherapyantiinflammatory/wish/276052328 2018-08-28 21:17:16 UTC https://padlet.com/venanzio_beth/140chemotherapyantiinflammatory/wish/276052328 Interactive Case Study Chapter 16 venanzio_beth https://padlet.com/venanzio_beth/140chemotherapyantiinflammatory/wish/276052405 Should the oncology patient in the above case study, take an anti-inflammatory like aspirin or Tylonel for pain associated with the treatment of chemotherapy while taking vincristine? ]]> 2018-08-28 21:17:42 UTC https://padlet.com/venanzio_beth/140chemotherapyantiinflammatory/wish/276052405 APA references venanzio_beth https://padlet.com/venanzio_beth/140chemotherapyantiinflammatory/wish/276054642 [1]  Karch, A. M. (2017). Focus on nursing pharmacology. Philadelphia: Wolters Kluwer.
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[2] Karch, A. M. (2017). Focus on nursing pharmacology. Philadelphia: Wolters Kluwer.
Ch.16
[3]  M. (2016, March 09). Cancer Drugs - Learn with Visual Mnemonics! Retrieved from https://www.youtube.com/watch?v=fIXBa2rExQI
[4]  Tamoxifen: Uses, Side Effects, and More. (n.d.). Retrieved from https://www.breastcancer.org/treatment/hormonal/serms/tamoxifen
[5]  Lopes, J. M. (2018, April 13). Lung Cancer Patients' Survival Is Better with Keytruda Than Chemo, Trial Shows. Retrieved from https://immuno-oncologynews.com/2018/04/13/keytruda-increases-lung-cancer-patients-survival-better-than-chemo/
[6]  Chemotherapy Safety | Chemotherapy. (n.d.). Retrieved August 28, 2018, from https://www.cancercouncil.com.au/cancer-information/cancer-treatment/chemotherapy/safety-precautions/
[7]  Karch, A. M. (2017). Focus on nursing pharmacology. Philadelphia: Wolters Kluwer.
Ch.14
[8] Karch, A. M. (2017). Focus on nursing pharmacology. Philadelphia: Wolters Kluwer.
Ch.16
[9] Philippidis, A. (2018, January 15). Top 10 Best-Selling Cancer Drugs, Q1–Q3 2017 | The Lists. Retrieved from https://www.genengnews.com/the-lists/top-10-best-selling-cancer-drugs-q1-q3-2017/77901033
[10] Chemotherapy Waste. (n.d.). Retrieved from http://hillman.upmc.com/patients/community-support/education/miscellaneous/chemotherapy-waste
]]> 2018-08-28 21:29:18 UTC https://padlet.com/venanzio_beth/140chemotherapyantiinflammatory/wish/276054642 [6] - Chemotherapy Safety venanzio_beth https://padlet.com/venanzio_beth/140chemotherapyantiinflammatory/wish/276059927 2018-08-28 22:03:06 UTC https://padlet.com/venanzio_beth/140chemotherapyantiinflammatory/wish/276059927 Interactive Case Study venanzio_beth https://padlet.com/venanzio_beth/140chemotherapyantiinflammatory/wish/276084617 A 41-year-old patient-care assistant working on an oncology floor developed an itchy rash approximately 30 minutes after emptying a commode of urine into a toilet [Kusnetz and Condon 2003]. She denied any direct contact with the urine, wore a protective gown and nitrile gloves, and followed hospital policy for the disposal of materials contaminated with antineoplastic drugs. The rash subsided after 1 to 2 days. Three weeks later, she had a similar reaction approximately 1 hour after performing the same procedure for another patient. Upon investigation, it was found that both hospital patients had recently been treated with vincristine and doxorubicin. The patientcare assistant had no other signs or symptoms and reported no changes in lifestyle and no history of allergies or recent infections. After treatment with diphenhydramine (intramuscular) and oral corticosteroids, her symptoms disappeared. Although the cause could not be definitely confirmed, both vincristine and doxorubicin have been associated with allergic reactions when given to patients. The aerosolization of the drug present in the urine may have provided enough exposure for symptoms to develop.

]]> 2018-08-29 01:07:39 UTC https://padlet.com/venanzio_beth/140chemotherapyantiinflammatory/wish/276084617 [10] - Chemotherapy at home venanzio_beth https://padlet.com/venanzio_beth/140chemotherapyantiinflammatory/wish/276091788 2018-08-29 01:48:12 UTC https://padlet.com/venanzio_beth/140chemotherapyantiinflammatory/wish/276091788