Poststreptococcal Glomerulonephritis Type III Immune Complex by Doris Anton https://padlet.com/danto8688/sjowndfumsidiso1 en-us 2023-03-16 19:33:59 UTC 2026-02-26 21:32:46 UTC hello@padlet.com What is PSGN? danto8688 https://padlet.com/danto8688/sjowndfumsidiso1/wish/2520145900 Poststreptococcal glomerulonephritis (PSGN) results from nephrogenic streptococci, specific strains of group A beta-hemolytic streptococci.  It is a result of an inflammatory response (type III hypersensitivity reaction) characterized by rapid deterioration of kidney function, specifically affecting the glomeruli and the small blood vessels of the kidneys.  PSGN is often seen in children six weeks post skin infection (impetigo) or 1-2 weeks after a sore throat.
NBK538255]]> 2023-03-17 00:40:17 UTC https://padlet.com/danto8688/sjowndfumsidiso1/wish/2520145900 danto8688 https://padlet.com/danto8688/sjowndfumsidiso1/wish/2520147684 2023-03-17 00:41:46 UTC https://padlet.com/danto8688/sjowndfumsidiso1/wish/2520147684 PSGN Risk Factors aomar0456 https://padlet.com/danto8688/sjowndfumsidiso1/wish/2520151857 Risk factors for PSGN is similar to group A strep pharyngitis or skin infection. PSGN is commonly seen in children, although it can occur in adults as well. Pharyngitis-associated PSGN is more commonly seen among children of early school age. Pyoderma-associated PSGN is most commonly seen among children of pre-school age. There is no known risk factors specifically related to PSGN. Yet, the risk of PSGN is increased if a nephritogenic strain of group A strep is introduced into a household. Patients are at increased risk of PSGN after having a strep throat, scarlet fever, or impetigo.

Centers for Disease Control and Prevention. (2022, June 27). Post-streptococcal glomerulonephritis: https://www.cdc.gov/groupastrep/diseases-hcp/post-streptococcal.html#:~:text=There%20are%20no%20known%20risk,is%20introduced%20into%20a%20household.

]]> 2023-03-17 00:45:26 UTC https://padlet.com/danto8688/sjowndfumsidiso1/wish/2520151857 Tissue/Organ Pathophysiology epscola99 https://padlet.com/danto8688/sjowndfumsidiso1/wish/2520152909 PSGN affects the kidneys, but it is not a strep infection of the kidneys. The body’s natural immune system can cause it after fighting strep throat, scarlet fever, or impetigo. The accumulation of antibodies containing streptococcal antigen immune complexes occurs within the kidney glomeruli. This causes the kidneys to become inflamed and makes them less capable of filtering urine. This can cause urinary retention which can swell the kidneys and increases sodium retention. This can be treated through the use of a diuretic medication.
https://www.mayoclinic.org/diseases-conditions/glomerulonephritis/symptoms-causes/syc-20355705 


]]> 2023-03-17 00:46:26 UTC https://padlet.com/danto8688/sjowndfumsidiso1/wish/2520152909 maffrunti123 https://padlet.com/danto8688/sjowndfumsidiso1/wish/2520153395 https://acrobat.adobe.com/id/urn:aaid:sc:VA6C2:bd74be42-34e4-460d-a089-516d7ba47f98]]> 2023-03-17 00:46:53 UTC https://padlet.com/danto8688/sjowndfumsidiso1/wish/2520153395 Clinical Manifestations danto8688 https://padlet.com/danto8688/sjowndfumsidiso1/wish/2520154571
  • Hematuria 
  • Edema, especially around the face and hands and feet
  • Decreased need to urinate
  • Oliguria (decreased urine output)
  • Fatigue 
  • Anemia 
  • Proteinuria 
  • CV: dyspnea, tachypnea, enlarged tender liver, hypertension (which can lead to headaches, vomiting, somnolence, and other CNS manifestations)

    • https://www.cdc.gov/groupastrep/diseases-public/post-streptococcal.html 
    https://pageburstls.elsevier.com/reader/books/9780323789905/epubcfi/6/140%5B%3Bvnd.vst.idref%3DCh039_1271-1283_B9780323789875000422%5D!/4/2%5Bc0039%5D/18/8/8/4%5BTABC000422t0010%5D/6/6/4/4/2%5Bu0045%5D/3:7%5Besi%2Con%5D 

    ]]>     2023-03-17 00:48:02 UTC https://padlet.com/danto8688/sjowndfumsidiso1/wish/2520154571     Expected Therapeutic Management kfern1896 https://padlet.com/danto8688/sjowndfumsidiso1/wish/2520155375 Post-streptococcal glomerulonephritis treatment consists of Beta-lactams antimicrobials. Some of the most commonly used types of B-lactams used by providers is Penicillin G Benzathine. Another medication used for treatment is erythromycin if the patient were to have a penicillin allergy. Apart from eradicating the microbe from the body, treatment plans include lessening physical symptoms. For example, it is a priority to control edema and blood pressure. Edema is managed by a diet with minimal amounts of salt and water intake; Blood pressure is controlled by use of diuretics which will increase urinary output. For patients experiencing more severe symptoms they may need dialysis, to limit physical exertion, and other medications like steroids, immunosuppressive agents, and plasmapheresis (Geetha M.D., 2021).
    .

    ]]>     2023-03-17 00:48:46 UTC https://padlet.com/danto8688/sjowndfumsidiso1/wish/2520155375     Does it conform to type III? epscola99 https://padlet.com/danto8688/sjowndfumsidiso1/wish/2520179065 PSGN conforms to the type III hypersensitivity reactions based upon the activation of the complement system. This is caused by the antigen/antibody reactivity found in the glomeruli located within the kidneys. The inflammatory response is a result of this activation.]]> 2023-03-17 01:10:09 UTC https://padlet.com/danto8688/sjowndfumsidiso1/wish/2520179065 Hypersensitivity Type III danto8688 https://padlet.com/danto8688/sjowndfumsidiso1/wish/2520187395 Antigens from streptococcal A and antibodies from glomeruli form complexes and deposit into the glomerulus of kidneys. Type III hypersensitivity is not organ specific, but symptoms appear where the complexes are deposited. In the case of PSGN, kidney function will be impaired. 

    https://www.ncbi.nlm.nih.gov/books/NBK333429/ ]]>     2023-03-17 01:14:54 UTC https://padlet.com/danto8688/sjowndfumsidiso1/wish/2520187395     Authors danto8688 https://padlet.com/danto8688/sjowndfumsidiso1/wish/2520196672 Doris Anton
    Mary Affrunti
    Ellen Scola
    Amber Camp
    Ayan Omar
    Karina Fernandez ]]>     2023-03-17 01:21:26 UTC https://padlet.com/danto8688/sjowndfumsidiso1/wish/2520196672     ambercamp https://padlet.com/danto8688/sjowndfumsidiso1/wish/2520199809 2023-03-17 01:23:47 UTC https://padlet.com/danto8688/sjowndfumsidiso1/wish/2520199809