https://padlet.com/norfre197/seszuzym6zpp en-us 2019-03-08 15:02:38 UTC 2024-07-23 03:36:17 UTC hello@padlet.com norfre197 https://padlet.com/norfre197/seszuzym6zpp/wish/339329144 The brain sends a nerve impulse to the neuromuscular junction, the nerve impulse causes voltage gated calcium ion channels to open which allow calcium ions to enter the neuron. This stimulates the release of the neutransmitter, acetylcholine, which is released into the cleft. Ach binds to a Ach receptor sight and activates voltage gated sodium channels, thiks pumps Na+ in and K+ out. Since, the K+ is pumped out of the cell it causes the cell interior to depolarize.The initial depolarization spreads to adjacent areas, opening voltage gated sodium channels and eventually initating an action potential that moves along the lengths of the sarcolemma. The Na+ concentrations caused by depolarization stimulate a change in membrane permeability by opening voltage gated K+ pumps which allow K+ to diffuse across the sarcolemma out of the muscle fiber, this is known as repolarization.]]> 2019-03-08 15:05:24 UTC https://padlet.com/norfre197/seszuzym6zpp/wish/339329144 norfre197 https://padlet.com/norfre197/seszuzym6zpp/wish/339329272 Step 1:  Action potential moves down the sarcolemma, and down the T-tubu

 

]]> 2019-03-08 15:05:37 UTC https://padlet.com/norfre197/seszuzym6zpp/wish/339329272 norfre197 https://padlet.com/norfre197/seszuzym6zpp/wish/339329423 Step 2: Trasmisson of the action potential along the T-tubules cause the adjacent Sarcoplasmic Reticulum, to release Ca2+ which flows into the cytosol.]]> 2019-03-08 15:05:52 UTC https://padlet.com/norfre197/seszuzym6zpp/wish/339329423 norfre197 https://padlet.com/norfre197/seszuzym6zpp/wish/339329545 Step 3 and 4: Ca2+ combines with troponin and removes the blocking action of tropomyosin by changing the shape of the actin so that the myosin binding sites are exposed. Then, the myosin binds to actin forming cross bridges and this is where contraction begins,

]]> 2019-03-08 15:06:04 UTC https://padlet.com/norfre197/seszuzym6zpp/wish/339329545 norfre197 https://padlet.com/norfre197/seszuzym6zpp/wish/339329735 step 1: The activated myosin head binds to actin forming a cross bridge, phosphate is released strengthening the bond between myosin and actin

]]> 2019-03-08 15:06:23 UTC https://padlet.com/norfre197/seszuzym6zpp/wish/339329735 norfre197 https://padlet.com/norfre197/seszuzym6zpp/wish/339329836 The power stroke: Myosin head pivots and pulls the actin filament toward M line. ]]> 2019-03-08 15:06:30 UTC https://padlet.com/norfre197/seszuzym6zpp/wish/339329836 norfre197 https://padlet.com/norfre197/seszuzym6zpp/wish/339329948 Step 3: Cross bridge detachment: ATP to attaches to myosin head, causing cross bridge to detach.]]> 2019-03-08 15:06:41 UTC https://padlet.com/norfre197/seszuzym6zpp/wish/339329948 norfre197 https://padlet.com/norfre197/seszuzym6zpp/wish/339330016 Step 4: Cocking of the myosin head: energy from hydrolysis of ATP cocks the myosin head into an energized state.]]> 2019-03-08 15:06:48 UTC https://padlet.com/norfre197/seszuzym6zpp/wish/339330016