Candyce McSwain by https://padlet.com/candyce_mcswain/sdo4lbcduknx Treponema pallidum en-us 2018-04-29 00:10:44 UTC 2023-01-24 03:33:14 UTC hello@padlet.com https://padlet-assets.s3.amazonaws.com/icons/Soccerball.png Pathogen: candyce_mcswain https://padlet.com/candyce_mcswain/sdo4lbcduknx/wish/256262127 Treponema pallidum]]> 2018-04-29 01:04:27 UTC https://padlet.com/candyce_mcswain/sdo4lbcduknx/wish/256262127 Microscopic Morphology candyce_mcswain https://padlet.com/candyce_mcswain/sdo4lbcduknx/wish/256262364 Treponema pallidum:
Thin, gram- negative spirochetes

Treponema pallidum is often invisible in a Gram stain due to its slender nature. 

DNA probes and immunofluorescent staining can be used to detect the pathogen.
]]> 2018-04-29 01:11:57 UTC https://padlet.com/candyce_mcswain/sdo4lbcduknx/wish/256262364 Disease Caused by the Pathogen, Treponema pallidum, in Humans: candyce_mcswain https://padlet.com/candyce_mcswain/sdo4lbcduknx/wish/256262459 Syphilis]]> 2018-04-29 01:15:17 UTC https://padlet.com/candyce_mcswain/sdo4lbcduknx/wish/256262459 Primary stage of Syphilis candyce_mcswain https://padlet.com/candyce_mcswain/sdo4lbcduknx/wish/256262665 The earliest indication of syphilis infection is the appearance of a hard chancre. 
Chancre- an injurious sore.
Chancre arises at the site of inoculation, after an incubation period from 9 days to 3 months.

Most chancres appear on the internal and external genitalia.
20% occur on the lips, nipples, fingers, or around the anus. 

  • The genital lesions tend to be painless.
  • Chancre heals without scarring in 3-6 weeks.
  • Healing is deceptive, the spirochete is entering another stage of systemic activity.
]]> 2018-04-29 01:20:54 UTC https://padlet.com/candyce_mcswain/sdo4lbcduknx/wish/256262665 candyce_mcswain https://padlet.com/candyce_mcswain/sdo4lbcduknx/wish/256262729 The infection of Treponema pallidum causes syphilis.
Syphilis is a sexually transmitted disease.
]]> 2018-04-29 01:22:40 UTC https://padlet.com/candyce_mcswain/sdo4lbcduknx/wish/256262729 Habitat candyce_mcswain https://padlet.com/candyce_mcswain/sdo4lbcduknx/wish/256262874 Humans are the only host of Treponema pallidum. 
(infection can be induced in laboratory animals)
]]> 2018-04-29 01:26:24 UTC https://padlet.com/candyce_mcswain/sdo4lbcduknx/wish/256262874 Syphilis candyce_mcswain https://padlet.com/candyce_mcswain/sdo4lbcduknx/wish/256263201 Wet mounts of fluid taken from syphilitic lesions may be examined with a dark-field microscopy for motile spirochetes.]]> 2018-04-29 01:33:01 UTC https://padlet.com/candyce_mcswain/sdo4lbcduknx/wish/256263201 Symptoms of Syphilis candyce_mcswain https://padlet.com/candyce_mcswain/sdo4lbcduknx/wish/256263680 Syphilis is known as,
“The Great Pretender,”because its symptoms can look like many other diseases.
 BUT:
syphilis usually follows a progression of stages that can last for weeks, months, or even years.
]]> 2018-04-29 01:44:59 UTC https://padlet.com/candyce_mcswain/sdo4lbcduknx/wish/256263680 Primary Syphilis Lesion: Chancre candyce_mcswain https://padlet.com/candyce_mcswain/sdo4lbcduknx/wish/256264249 2018-04-29 02:01:12 UTC https://padlet.com/candyce_mcswain/sdo4lbcduknx/wish/256264249 Secondary Syphilis candyce_mcswain https://padlet.com/candyce_mcswain/sdo4lbcduknx/wish/256264410 This stage appears 3 weeks - 6 months after the chancre heals.
  • Many systems of the body have been invaded by this time. 
  • Signs and symptoms are more abundant and have intensified. 
  • New symptoms include; fever, headache, sore throat,  lymphadenopathy, and a red or brown rash occurs on all skin surfaces.
  • The skin rash does not hurt or itch and can last for months.
Complications of secondary syphilis - can occur in the bones, hair follicles, joints, eyes, liver, and brain and remain for years. 

]]> 2018-04-29 02:05:41 UTC https://padlet.com/candyce_mcswain/sdo4lbcduknx/wish/256264410 Latency & Tertiary Syphilis candyce_mcswain https://padlet.com/candyce_mcswain/sdo4lbcduknx/wish/256265242 The later stages of syphilis symptoms that occur 6 months- 20 years. 

Latency- 6 months to 8 or more years.
Tertiary-  variable up to 20 years

About 30 % of infections enter a highly varied latency period that can last 20 years or longer.

The Following symptoms can occur in
 this stage of syphilis:
  • Swollen tumors called gummas develop in the tissues including; skin, bone, cartilage, and liver. The tumors are usually benign, occasionally lead to death, but can impair function.
  • Neural and cardiovascular complications .
  • Areas of destruction of the spinal cord can lead to muscle wasting, loss of activity and loss of coordination.
  • Severe headaches, convulsions, mental derangements, atrophy of the optic nerve, blindness, and Argyll-Robertson pupil reaction.
]]> 2018-04-29 02:29:24 UTC https://padlet.com/candyce_mcswain/sdo4lbcduknx/wish/256265242 Congenital Syphilis candyce_mcswain https://padlet.com/candyce_mcswain/sdo4lbcduknx/wish/256266220 This occurs when :
Treponema pallidum passes from a preganant woman's circulation into the placenta and is carried throughout the fetal tissues.]]> 2018-04-29 02:54:15 UTC https://padlet.com/candyce_mcswain/sdo4lbcduknx/wish/256266220 Treatment candyce_mcswain https://padlet.com/candyce_mcswain/sdo4lbcduknx/wish/256266355
  • Penicillin G is the choice of treatment in all stages and forms of syphilis.
    • It is given in large doses with benzathine or procaine to maintain a blood level lethal to treponeme for at least 7 days.

    • Alternative drugs tetracycline and doxycycline are less effective treatments for syphilis and only given if the infected has a documented penicillin allergy.  
    ]]>     2018-04-29 02:57:48 UTC https://padlet.com/candyce_mcswain/sdo4lbcduknx/wish/256266355     Prevention candyce_mcswain https://padlet.com/candyce_mcswain/sdo4lbcduknx/wish/256266419 Use of latex condoms reduces the chance of infection.
    However, it does not eliminate the chance infection because Treponema pallidum may infect sites that are not normally protected by a condom.
    Control of syphilis relies on the detection and treatment ]]>     2018-04-29 02:59:36 UTC https://padlet.com/candyce_mcswain/sdo4lbcduknx/wish/256266419     Secondary Syphilis: Generalized Body Rash candyce_mcswain https://padlet.com/candyce_mcswain/sdo4lbcduknx/wish/256267305 2018-04-29 03:22:36 UTC https://padlet.com/candyce_mcswain/sdo4lbcduknx/wish/256267305 Treponemes: candyce_mcswain https://padlet.com/candyce_mcswain/sdo4lbcduknx/wish/256269694 Are  members of the Genus Treponema.

    These pathogens are strict parasites with complex growth requirements.

     Treponemes are thin, coiled bacteria.  They live in the oral cavity, intestinal tract, and perigenital regions of animal and humans. 

    Diseases that are cause by Treponema are called treponematoses.

    The subspecies Treponema pallidum pallidum
    • is responsible for congenital and venereal syphilis.
    • is an extremely fastidious and sensitive bacterium that cannot survive long outside of its host.
    ]]>     2018-04-29 04:09:16 UTC https://padlet.com/candyce_mcswain/sdo4lbcduknx/wish/256269694     WHO? HOW? candyce_mcswain https://padlet.com/candyce_mcswain/sdo4lbcduknx/wish/256270000 Humans can become infected in the following ways:

    Syphilis can be transmitted from person to person by direct contact with a syphilitic sore, known as a chancre.

    Transmitted sexually from infected partner.

    Passed from infected mother to fetus in utero (Congenital Syphilis ).

    Very rare ways to become infected: blood transfusion or exposure to fomites.]]>     2018-04-29 04:15:11 UTC https://padlet.com/candyce_mcswain/sdo4lbcduknx/wish/256270000     candyce_mcswain https://padlet.com/candyce_mcswain/sdo4lbcduknx/wish/256272726 2018-04-29 05:10:44 UTC https://padlet.com/candyce_mcswain/sdo4lbcduknx/wish/256272726 Tertiary Syphilis: GUMMAS candyce_mcswain https://padlet.com/candyce_mcswain/sdo4lbcduknx/wish/256273460 2018-04-29 05:27:17 UTC https://padlet.com/candyce_mcswain/sdo4lbcduknx/wish/256273460 candyce_mcswain https://padlet.com/candyce_mcswain/sdo4lbcduknx/wish/256274310 2018-04-29 05:48:03 UTC https://padlet.com/candyce_mcswain/sdo4lbcduknx/wish/256274310 Classification of Treponema pallidum candyce_mcswain https://padlet.com/candyce_mcswain/sdo4lbcduknx/wish/256274630 Kingdom: Bacteria
    • Phylum: Spirochetes
    • Class: Spirochaetes
    • Order: Spirochaetales
    • Family: Spirochaetacecae
    • Genus: Treponema
    -Treponema is one of the 3 genera of the Phylum Spirochetes.
    -The spirochetes are classified in the Phylum Spirochetes
    • These bacteria are distinguished by their shape and mode of movement (locomotion). 
    • Their periplasmic flagella enables movement of the slender twisted cells.
    • Spirochetes are bacteria with gram-negative cell wall structure.
    ]]>     2018-04-29 05:56:30 UTC https://padlet.com/candyce_mcswain/sdo4lbcduknx/wish/256274630