https://padlet.com/slenacaldwell10/sdd54phktj9awo56 Made with serendipity en-us 2022-06-25 23:09:55 UTC 2022-06-29 03:12:00 UTC hello@padlet.com slenacaldwell10 https://padlet.com/slenacaldwell10/sdd54phktj9awo56/wish/2230455614 Take online courses. earn college credit. Research Schools, Degrees & Careers. Study.com | Take Online Courses. Earn College Credit. Research Schools, Degrees & Careers. (n.d.). Retrieved June 25, 2022, from https://study.com/academy/answer/why-don-t-children-with-digeorge-syndrome-reject-their-thymus-graft.html

Kraus, C., Vanicek, T., Weidenauer, A., Khanaqa, T., Stamenkovic, M., Lanzenberger, R., Willeit, M., & Kasper, S. (2018). DiGeorge syndrome. Wiener Klinische Wochenschrift, 130(7-8), 283–287. https://doi.org/10.1007/s00508-018-1335-y

Giardino, G., Radwan, N., Koletsi, P., Morrogh, D. M., Adams, S., Ip, W., Worth, A., Jones, A., Meyer-Parsonson, I., Gaspar, H. B., Gilmour, K., Davies, E. G., & Ladomenou, F. (2019). Clinical and immunological features in a cohort of patients with partial digeorge syndrome followed at a single center. Blood, 133(24), 2586–2596. https://doi.org/10.1182/blood.2018885244

Cheprasov, A. (2021, October 2). Tetralogy of Fallot: Definition, Causes and Treatment. Study.com | Take Online Courses. Earn College Credit. Research Schools, Degrees & Careers. Retrieved June 27, 2022, from https://study.com/academy/lesson/tetralogy-of-fallot-definition-causes-and-treatment.html

Medical Professional, C. C. (2020, January 13). DiGeorge syndrome: Symptoms, causes, treatment & complications. Cleveland Clinic. Retrieved June 27, 2022, from https://my.clevelandclinic.org/health/diseases/21182-digeorge-syndrome ]]> 2022-06-25 23:58:13 UTC https://padlet.com/slenacaldwell10/sdd54phktj9awo56/wish/2230455614 slenacaldwell10 https://padlet.com/slenacaldwell10/sdd54phktj9awo56/wish/2230457979 DiGeorge Syndrome results from a defect on chromosome 22. It is from the deletion of gene 22q11.2. (Blood, 2019)]]> 2022-06-26 00:13:04 UTC https://padlet.com/slenacaldwell10/sdd54phktj9awo56/wish/2230457979 slenacaldwell10 https://padlet.com/slenacaldwell10/sdd54phktj9awo56/wish/2230458332 The thymus is the organ in which T cells are made. Many people with complete DiGeorge Syndrome get a thymus transplant. Unlike many transplants, recipients are unlikely to reject the transplant, since their body is unable to make the T cells that would be responsible for rejecting it. (study.com)]]> 2022-06-26 00:15:05 UTC https://padlet.com/slenacaldwell10/sdd54phktj9awo56/wish/2230458332 slenacaldwell10 https://padlet.com/slenacaldwell10/sdd54phktj9awo56/wish/2230463624 Without T cell formation, the body is unable to fight off pathogens. Due to this, early diagnoses of DiGeorge Syndrome in infants typically present with triad immunodeficiency (75%). On top of that, congenital heart issues (75%) are typically present. In later diagnoses, psychological disorders are usually present (60%). A commonality with the disorder is also visual abnormalities to the spine, face, ears, noses, and eyes (abnormally wide spacing). The severity of the symptoms present depends on the genotype. (The European Journal of Medicine, 2018)]]> 2022-06-26 00:48:14 UTC https://padlet.com/slenacaldwell10/sdd54phktj9awo56/wish/2230463624 hargravesstarr https://padlet.com/slenacaldwell10/sdd54phktj9awo56/wish/2231622295  Anonymous Jane is what we call a 22 Qutie. In utero, Anonymous Jane's parents found out that their precious babe had Tetralogy of Fallot and Absent Pulmonary Valve. Anonymous Jane was diagnosed with DGS a week after birth. She is now 7 years old and thriving! In her case, she has Velocardiofacial Syndrome (apart of DGS; includes smooth philtrum, hooded eyes, small eye openings, flat midface, thin upper lip, small and lower ear canals, and cleft palate), low muscle tone, heart complications, G-Tube (due to low muscle tone in her face she pockets food in her cheek), and a speech impediment. Her parent's are waiting for results regarding her Calcium levels in her blood and tests to see if she has Osteogenesis Imperfecta, commonly known as Brittle Bone. Each case is very different, but this is Anonymous Jane's story.]]> 2022-06-27 16:38:58 UTC https://padlet.com/slenacaldwell10/sdd54phktj9awo56/wish/2231622295 hargravesstarr https://padlet.com/slenacaldwell10/sdd54phktj9awo56/wish/2231645154 This is a short video that well summarizes what DiGeorge Syndrome is and what can come along with it.]]> 2022-06-27 17:10:08 UTC https://padlet.com/slenacaldwell10/sdd54phktj9awo56/wish/2231645154 hargravesstarr https://padlet.com/slenacaldwell10/sdd54phktj9awo56/wish/2231661834 2022-06-27 17:34:56 UTC https://padlet.com/slenacaldwell10/sdd54phktj9awo56/wish/2231661834 hargravesstarr https://padlet.com/slenacaldwell10/sdd54phktj9awo56/wish/2231662256 2022-06-27 17:35:42 UTC https://padlet.com/slenacaldwell10/sdd54phktj9awo56/wish/2231662256 hargravesstarr https://padlet.com/slenacaldwell10/sdd54phktj9awo56/wish/2231665675 2022-06-27 17:41:32 UTC https://padlet.com/slenacaldwell10/sdd54phktj9awo56/wish/2231665675 hargravesstarr https://padlet.com/slenacaldwell10/sdd54phktj9awo56/wish/2231665793 2022-06-27 17:41:43 UTC https://padlet.com/slenacaldwell10/sdd54phktj9awo56/wish/2231665793 hargravesstarr https://padlet.com/slenacaldwell10/sdd54phktj9awo56/wish/2231681265 Includes 4 components:
-Ventricular Septal Defect: the ventricles of the heart are separated by a hole in the tissue wall (Cheprasov)
-Overriding Aorta: aorta is positioned between both ventricles in the heart when it should be positioned on the left side (Cheprasov)
-Pulmonary Valve (or Infundibular) Stenosis: narrowing of the ventricular valve causing restrictive outflow (Cheprasov)
-Right Ventricular Hypertrophy: right ventricle wall has an increase in thickness (Cheprasov)]]> 2022-06-27 18:04:04 UTC https://padlet.com/slenacaldwell10/sdd54phktj9awo56/wish/2231681265 hargravesstarr https://padlet.com/slenacaldwell10/sdd54phktj9awo56/wish/2231687923 2022-06-27 18:13:51 UTC https://padlet.com/slenacaldwell10/sdd54phktj9awo56/wish/2231687923 hargravesstarr https://padlet.com/slenacaldwell10/sdd54phktj9awo56/wish/2231706239 DGS cannot be cured or prevented (it's inherited). However, action can be taken for the symptoms of DGS. Each individual diagnosed with DGS would have a different plan as DGS is not the same for everyone. This could include heart surgery, thymus transplant, vaccinations to protect the immune system, physical therapy, speech therapy, calcium supplements, ear tubes, and cleft palate surgery (Medical Professional).]]> 2022-06-27 18:42:19 UTC https://padlet.com/slenacaldwell10/sdd54phktj9awo56/wish/2231706239