Biochemistry Recitation 8 by Arya Rao https://padlet.com/asr2210/sd3c864b5lw860hb en-us 2021-11-08 23:51:34 UTC 2021-11-08 23:56:24 UTC hello@padlet.com Aconitase https://padlet.com/asr2210/sd3c864b5lw860hb/wish/1876623348 Can only bind in one orientation only.]]> 2021-11-08 23:54:42 UTC https://padlet.com/asr2210/sd3c864b5lw860hb/wish/1876623348 orientation https://padlet.com/asr2210/sd3c864b5lw860hb/wish/1876623993 that due to all these different specific interactions that the enzyme makes w the ligand, the ligand is held in place in a specific orientation that differentiates one end of the ligand from the other]]> 2021-11-08 23:55:09 UTC https://padlet.com/asr2210/sd3c864b5lw860hb/wish/1876623993 though citrate is symmetrical, aconitase's histidine and arginine hold it in a very specific position so it can interact with the Fe-S complex https://padlet.com/asr2210/sd3c864b5lw860hb/wish/1876623995 2021-11-08 23:55:09 UTC https://padlet.com/asr2210/sd3c864b5lw860hb/wish/1876623995 today i learned that https://padlet.com/asr2210/sd3c864b5lw860hb/wish/1876624022 making a model super big may make distances between residues and the substrate seem larger than they actually are]]> 2021-11-08 23:55:10 UTC https://padlet.com/asr2210/sd3c864b5lw860hb/wish/1876624022 ummm...a bit zoomed out today but learned that there were this cool feature that holla everybody to the same place which is dope https://padlet.com/asr2210/sd3c864b5lw860hb/wish/1876624668 2021-11-08 23:55:35 UTC https://padlet.com/asr2210/sd3c864b5lw860hb/wish/1876624668 Complex II https://padlet.com/asr2210/sd3c864b5lw860hb/wish/1876624972 - Does not pump protons across
- Ferries protons from FAD+]]> 2021-11-08 23:55:48 UTC https://padlet.com/asr2210/sd3c864b5lw860hb/wish/1876624972 Cluster https://padlet.com/asr2210/sd3c864b5lw860hb/wish/1876625054 The carboxyl and OH group interacts with the Fe-S cluster to stabilize itself as well as H-bonding with the imidazole. ]]> 2021-11-08 23:55:51 UTC https://padlet.com/asr2210/sd3c864b5lw860hb/wish/1876625054 The main purpose of aconitase is to catalyze the formation of citrate to isocitrate. https://padlet.com/asr2210/sd3c864b5lw860hb/wish/1876625831 2021-11-08 23:56:24 UTC https://padlet.com/asr2210/sd3c864b5lw860hb/wish/1876625831