https://padlet.com/hermann68/s9wt6pwyyjqg Exam 1 en-us 2017-10-01 00:06:33 UTC 2017-10-01 01:40:50 UTC hello@padlet.com hermann68 https://padlet.com/hermann68/s9wt6pwyyjqg/wish/192715163 Opioid]]> 2017-10-01 00:11:33 UTC https://padlet.com/hermann68/s9wt6pwyyjqg/wish/192715163 hermann68 https://padlet.com/hermann68/s9wt6pwyyjqg/wish/192715169 Binds with mu opioid receptors to mimic actions of naturally occurring opioids (endorphins, enkephalins)]]> 2017-10-01 00:11:57 UTC https://padlet.com/hermann68/s9wt6pwyyjqg/wish/192715169 hermann68 https://padlet.com/hermann68/s9wt6pwyyjqg/wish/192715205 Severe pain
Moderate to severe pain]]> 2017-10-01 00:13:09 UTC https://padlet.com/hermann68/s9wt6pwyyjqg/wish/192715205 hermann68 https://padlet.com/hermann68/s9wt6pwyyjqg/wish/192715214 respiratory depression
sedation, dizziness, lightheadedness, drowsiness
constipation
nausea, vomiting
orthostatic hypotension
urinary retention
cough suppression]]> 2017-10-01 00:13:36 UTC https://padlet.com/hermann68/s9wt6pwyyjqg/wish/192715214 hermann68 https://padlet.com/hermann68/s9wt6pwyyjqg/wish/192715337 *Potential for abuse
*Tolerance with continued use and *cross tolerance with other opioids
*do not use in patients with respiratory issues (asthma), elevated intracranial pressure, slow bowel motility]]> 2017-10-01 00:16:52 UTC https://padlet.com/hermann68/s9wt6pwyyjqg/wish/192715337 hermann68 https://padlet.com/hermann68/s9wt6pwyyjqg/wish/192715397 *Assess respiratory rate and depth prior to and after administration
*Have antidote (Naloxone, Narcan) available)
*Risk for falls
*Timing of dose (do not push an opioid too fast]]> 2017-10-01 00:18:41 UTC https://padlet.com/hermann68/s9wt6pwyyjqg/wish/192715397 hermann68 https://padlet.com/hermann68/s9wt6pwyyjqg/wish/192715498 Opioid Antagonist]]> 2017-10-01 00:21:21 UTC https://padlet.com/hermann68/s9wt6pwyyjqg/wish/192715498 hermann68 https://padlet.com/hermann68/s9wt6pwyyjqg/wish/192715521 *Competitive antagonist that knocks opioids out of the receptors
*Blocks opioid receptor]]> 2017-10-01 00:22:02 UTC https://padlet.com/hermann68/s9wt6pwyyjqg/wish/192715521 hermann68 https://padlet.com/hermann68/s9wt6pwyyjqg/wish/192715567 Reversal of Opioid overdose]]> 2017-10-01 00:23:03 UTC https://padlet.com/hermann68/s9wt6pwyyjqg/wish/192715567 hermann68 https://padlet.com/hermann68/s9wt6pwyyjqg/wish/192715577 Opioid withdrawl or opioid abstinence syndrome including SEVERE PAIN]]> 2017-10-01 00:23:25 UTC https://padlet.com/hermann68/s9wt6pwyyjqg/wish/192715577 hermann68 https://padlet.com/hermann68/s9wt6pwyyjqg/wish/192715605 Those with opioid dependence (careful administration wit help of provider if not an emergency]]> 2017-10-01 00:24:11 UTC https://padlet.com/hermann68/s9wt6pwyyjqg/wish/192715605 hermann68 https://padlet.com/hermann68/s9wt6pwyyjqg/wish/192715684 *Monitor blood pressure and vital signs
*Have emergency supplies ready for further resuscitation
*Watch after administration for continued effectiveness of Narcan if opioid is long acting]]> 2017-10-01 00:25:35 UTC https://padlet.com/hermann68/s9wt6pwyyjqg/wish/192715684 hermann68 https://padlet.com/hermann68/s9wt6pwyyjqg/wish/192715742 In a class of its own]]> 2017-10-01 00:27:10 UTC https://padlet.com/hermann68/s9wt6pwyyjqg/wish/192715742 hermann68 https://padlet.com/hermann68/s9wt6pwyyjqg/wish/192715749 *Inhibits production of prostaglandins in the CNS through COX
     *relieves pain
     *reduces fever
*No peripheral inhibition (not out in the tissue like NSAIDS)
     *No anti-inflammatory effects
*No anticoagulant effects


]]> 2017-10-01 00:27:24 UTC https://padlet.com/hermann68/s9wt6pwyyjqg/wish/192715749 hermann68 https://padlet.com/hermann68/s9wt6pwyyjqg/wish/192715791 *Mild Pain or moderate pain
*Drug of choice for mild/mod pain in older adults and peds
*Added to opioids to increase overall analgesia.

]]> 2017-10-01 00:29:07 UTC https://padlet.com/hermann68/s9wt6pwyyjqg/wish/192715791 hermann68 https://padlet.com/hermann68/s9wt6pwyyjqg/wish/192715843 *At safe doses, on of the best tolerated meds
*Drug of choice for peds and older adults with pain
*Liver damage with high doses]]> 2017-10-01 00:30:57 UTC https://padlet.com/hermann68/s9wt6pwyyjqg/wish/192715843 hermann68 https://padlet.com/hermann68/s9wt6pwyyjqg/wish/192715868 *Excessive acetaminophen use is the number 1 cause of acute hepatic failure in  the US
*Do not drink alcohol with Aceta.
*Do not use in those with Liver disease

]]> 2017-10-01 00:31:52 UTC https://padlet.com/hermann68/s9wt6pwyyjqg/wish/192715868 hermann68 https://padlet.com/hermann68/s9wt6pwyyjqg/wish/192715914 *4000mg (4g) is max dose in 24 hours
*Antidote Acetylcysteine (Mucomyst) with overdose]]> 2017-10-01 00:33:26 UTC https://padlet.com/hermann68/s9wt6pwyyjqg/wish/192715914 hermann68 https://padlet.com/hermann68/s9wt6pwyyjqg/wish/192715992 Non Steroidal Anti-Inflammatory (NSAID)

]]> 2017-10-01 00:35:57 UTC https://padlet.com/hermann68/s9wt6pwyyjqg/wish/192715992 hermann68 https://padlet.com/hermann68/s9wt6pwyyjqg/wish/192716004 Non-selectively prevents COX enzymes from releasing prostaglandins thus reducing pain, fever, and inflammation]]> 2017-10-01 00:36:20 UTC https://padlet.com/hermann68/s9wt6pwyyjqg/wish/192716004 hermann68 https://padlet.com/hermann68/s9wt6pwyyjqg/wish/192716025 Gastric Irritation and bleeding
Kidney failure in those with kidney problems

]]> 2017-10-01 00:37:01 UTC https://padlet.com/hermann68/s9wt6pwyyjqg/wish/192716025 hermann68 https://padlet.com/hermann68/s9wt6pwyyjqg/wish/192716054 *Do not use in patients with kidney problems
*Do not use in patients needing to take aspirin for cardiac health]]> 2017-10-01 00:37:49 UTC https://padlet.com/hermann68/s9wt6pwyyjqg/wish/192716054 hermann68 https://padlet.com/hermann68/s9wt6pwyyjqg/wish/192716092 *Watch for GI bleeding
*Monitor kidney function]]> 2017-10-01 00:39:00 UTC https://padlet.com/hermann68/s9wt6pwyyjqg/wish/192716092 hermann68 https://padlet.com/hermann68/s9wt6pwyyjqg/wish/192716123 COX 2 Inhibitor]]> 2017-10-01 00:40:04 UTC https://padlet.com/hermann68/s9wt6pwyyjqg/wish/192716123 hermann68 https://padlet.com/hermann68/s9wt6pwyyjqg/wish/192716131 *Selectively prevents COX2 enzyme from releasing prostaglandins thus reducing pain, fever, and inflammation]]> 2017-10-01 00:40:18 UTC https://padlet.com/hermann68/s9wt6pwyyjqg/wish/192716131 hermann68 https://padlet.com/hermann68/s9wt6pwyyjqg/wish/192716171 Patients with low cardiovascular risk who require NSAID therapy and are at increased risk for GI toxicity]]> 2017-10-01 00:41:31 UTC https://padlet.com/hermann68/s9wt6pwyyjqg/wish/192716171 hermann68 https://padlet.com/hermann68/s9wt6pwyyjqg/wish/192716191 *Gastric irritation (but less than regualr NSAID
*Kidney problems
*Cardiovascular]]> 2017-10-01 00:42:10 UTC https://padlet.com/hermann68/s9wt6pwyyjqg/wish/192716191 hermann68 https://padlet.com/hermann68/s9wt6pwyyjqg/wish/192716209 Do not use in patients with kidney problems

*Do mot use in those with cardiovascular risks]]> 2017-10-01 00:42:44 UTC https://padlet.com/hermann68/s9wt6pwyyjqg/wish/192716209 hermann68 https://padlet.com/hermann68/s9wt6pwyyjqg/wish/192716252 Same as regular NSAID + Cardiovascular changes]]> 2017-10-01 00:44:00 UTC https://padlet.com/hermann68/s9wt6pwyyjqg/wish/192716252 hermann68 https://padlet.com/hermann68/s9wt6pwyyjqg/wish/192716393 2017-10-01 00:47:27 UTC https://padlet.com/hermann68/s9wt6pwyyjqg/wish/192716393 hermann68 https://padlet.com/hermann68/s9wt6pwyyjqg/wish/192716399 NSAID, Salicylate]]> 2017-10-01 00:47:40 UTC https://padlet.com/hermann68/s9wt6pwyyjqg/wish/192716399 hermann68 https://padlet.com/hermann68/s9wt6pwyyjqg/wish/192716408 Inhibition of COX-1 and COX-2 that leads to reduced prostaglandin synthesis. The analgesic action of aspirin occurs peripherally with limited action in the CNS]]> 2017-10-01 00:47:56 UTC https://padlet.com/hermann68/s9wt6pwyyjqg/wish/192716408 hermann68 https://padlet.com/hermann68/s9wt6pwyyjqg/wish/192716487 *Pain, mild to moderate
*Prevention for CV risk]]> 2017-10-01 00:50:36 UTC https://padlet.com/hermann68/s9wt6pwyyjqg/wish/192716487 hermann68 https://padlet.com/hermann68/s9wt6pwyyjqg/wish/192716503 *Bleeding (more so than NSAIDS
*Tinnitus on overdose
*Same as other nonselective NSAIDS]]> 2017-10-01 00:51:09 UTC https://padlet.com/hermann68/s9wt6pwyyjqg/wish/192716503 hermann68 https://padlet.com/hermann68/s9wt6pwyyjqg/wish/192716538 Renal function]]> 2017-10-01 00:52:22 UTC https://padlet.com/hermann68/s9wt6pwyyjqg/wish/192716538 hermann68 https://padlet.com/hermann68/s9wt6pwyyjqg/wish/192716545 Bleeding precautions]]> 2017-10-01 00:52:38 UTC https://padlet.com/hermann68/s9wt6pwyyjqg/wish/192716545 hermann68 https://padlet.com/hermann68/s9wt6pwyyjqg/wish/192716575 2017-10-01 00:53:35 UTC https://padlet.com/hermann68/s9wt6pwyyjqg/wish/192716575 hermann68 https://padlet.com/hermann68/s9wt6pwyyjqg/wish/192716580 Opioid Agonist-Antagonist]]> 2017-10-01 00:53:41 UTC https://padlet.com/hermann68/s9wt6pwyyjqg/wish/192716580 hermann68 https://padlet.com/hermann68/s9wt6pwyyjqg/wish/192716607 Antagonist at Mu receptor, Agonist at Kappa]]> 2017-10-01 00:54:22 UTC https://padlet.com/hermann68/s9wt6pwyyjqg/wish/192716607 hermann68 https://padlet.com/hermann68/s9wt6pwyyjqg/wish/192716637 *Moderate to Severe pain

]]> 2017-10-01 00:55:44 UTC https://padlet.com/hermann68/s9wt6pwyyjqg/wish/192716637 hermann68 https://padlet.com/hermann68/s9wt6pwyyjqg/wish/192716651 *Pentazocine causes less nausea, vomiting, and respiratory depression than morphine
*Drowsiness and dizziness are common]]> 2017-10-01 00:56:10 UTC https://padlet.com/hermann68/s9wt6pwyyjqg/wish/192716651 hermann68 https://padlet.com/hermann68/s9wt6pwyyjqg/wish/192716704 *Can initiate withdrawal in Opioid dependent patients
*Asthma, COPD, respiratory disorders
*Do not administer with other CNS depressants (including alcohol)]]> 2017-10-01 00:57:53 UTC https://padlet.com/hermann68/s9wt6pwyyjqg/wish/192716704 hermann68 https://padlet.com/hermann68/s9wt6pwyyjqg/wish/192716760 CNS depression system precautions (side rails up, etc)]]> 2017-10-01 00:59:39 UTC https://padlet.com/hermann68/s9wt6pwyyjqg/wish/192716760 hermann68 https://padlet.com/hermann68/s9wt6pwyyjqg/wish/192716811 2017-10-01 01:01:01 UTC https://padlet.com/hermann68/s9wt6pwyyjqg/wish/192716811 hermann68 https://padlet.com/hermann68/s9wt6pwyyjqg/wish/192716841 Serotonin (5-HT1) receptor agonist]]> 2017-10-01 01:01:58 UTC https://padlet.com/hermann68/s9wt6pwyyjqg/wish/192716841 hermann68 https://padlet.com/hermann68/s9wt6pwyyjqg/wish/192716860 Binds to receptors on intracranial blood vessels and causes vasoconstriction, thus reducing headache pain ]]> 2017-10-01 01:02:49 UTC https://padlet.com/hermann68/s9wt6pwyyjqg/wish/192716860 hermann68 https://padlet.com/hermann68/s9wt6pwyyjqg/wish/192716896 Stop an an ongoing migraine attack]]> 2017-10-01 01:03:46 UTC https://padlet.com/hermann68/s9wt6pwyyjqg/wish/192716896 hermann68 https://padlet.com/hermann68/s9wt6pwyyjqg/wish/192716915 *Often associated with vasoconstriction
*Heavy arms, chest pressure, angina, dizziness, tingling]]> 2017-10-01 01:04:14 UTC https://padlet.com/hermann68/s9wt6pwyyjqg/wish/192716915 hermann68 https://padlet.com/hermann68/s9wt6pwyyjqg/wish/192716962 *interacts with other meds causing vasoconstriction, including some migraine meds
*Contraindicated in any condition where vasoconstriction could be dangerous (HTN)]]> 2017-10-01 01:05:33 UTC https://padlet.com/hermann68/s9wt6pwyyjqg/wish/192716962 hermann68 https://padlet.com/hermann68/s9wt6pwyyjqg/wish/192716997 *Monitor vital signs, especially for those at cardiovascular
*If angina occurs, must rule out cardiac ischemia through EKG]]> 2017-10-01 01:06:39 UTC https://padlet.com/hermann68/s9wt6pwyyjqg/wish/192716997 hermann68 https://padlet.com/hermann68/s9wt6pwyyjqg/wish/192717092 2017-10-01 01:09:21 UTC https://padlet.com/hermann68/s9wt6pwyyjqg/wish/192717092 hermann68 https://padlet.com/hermann68/s9wt6pwyyjqg/wish/192717108 Mixed opioid-nonopioid analgesic
*Centrally acting analgesic
*Technically not an opioid ]]> 2017-10-01 01:09:51 UTC https://padlet.com/hermann68/s9wt6pwyyjqg/wish/192717108 hermann68 https://padlet.com/hermann68/s9wt6pwyyjqg/wish/192717214 *Binds to selected opioid receptors while also blocking reuptake of norepinephrine and serotonin in the CNS]]> 2017-10-01 01:12:24 UTC https://padlet.com/hermann68/s9wt6pwyyjqg/wish/192717214 hermann68 https://padlet.com/hermann68/s9wt6pwyyjqg/wish/192717237 Moderate to moderately severe pain/ Chronic pain]]> 2017-10-01 01:13:03 UTC https://padlet.com/hermann68/s9wt6pwyyjqg/wish/192717237 hermann68 https://padlet.com/hermann68/s9wt6pwyyjqg/wish/192717254 Dizziness, nausea, vomiting, constipation, lethargy respiratory depression (rarely)]]> 2017-10-01 01:13:41 UTC https://padlet.com/hermann68/s9wt6pwyyjqg/wish/192717254 hermann68 https://padlet.com/hermann68/s9wt6pwyyjqg/wish/192717284 *Hx of substance abuse (alcohol and tramadol bad mix) or suicidal thoughts (risk of OD)
*Caution in renal hepatic impairment and increased intracranial pressure
*Don't take if hx of seizure (lowers seizure threshold
*Older adults]]> 2017-10-01 01:14:31 UTC https://padlet.com/hermann68/s9wt6pwyyjqg/wish/192717284 hermann68 https://padlet.com/hermann68/s9wt6pwyyjqg/wish/192717356 Naloxone (Narcan) only moderately effective in reducing respiratory depression
*Seizure precaution]]> 2017-10-01 01:16:09 UTC https://padlet.com/hermann68/s9wt6pwyyjqg/wish/192717356 hermann68 https://padlet.com/hermann68/s9wt6pwyyjqg/wish/192717874 2017-10-01 01:32:12 UTC https://padlet.com/hermann68/s9wt6pwyyjqg/wish/192717874 hermann68 https://padlet.com/hermann68/s9wt6pwyyjqg/wish/192717897 2017-10-01 01:33:04 UTC https://padlet.com/hermann68/s9wt6pwyyjqg/wish/192717897 hermann68 https://padlet.com/hermann68/s9wt6pwyyjqg/wish/192717927 2017-10-01 01:34:12 UTC https://padlet.com/hermann68/s9wt6pwyyjqg/wish/192717927 hermann68 https://padlet.com/hermann68/s9wt6pwyyjqg/wish/192717930 2017-10-01 01:34:19 UTC https://padlet.com/hermann68/s9wt6pwyyjqg/wish/192717930 hermann68 https://padlet.com/hermann68/s9wt6pwyyjqg/wish/192717942 2017-10-01 01:34:40 UTC https://padlet.com/hermann68/s9wt6pwyyjqg/wish/192717942