DRUG STUDY by Rey Ann Pangilinan

Generic: Amlodipine

rapangilinan — 2021-09-13 09:20:47 UTC

Brand: Norvasc

Stock dosage: PO - 2.5mg, 5mg, 10mg

CLASSIFICATION

rapangilinan — 2021-09-13 09:22:50 UTC

Therapeutic: antihypertensives

Pharmacologic: calcium channel blockers

MECHANISM OF ACTION

rapangilinan — 2021-09-13 09:23:26 UTC

Inhibits the transport of calcium into myocardial and vascular smooth muscle cells, resulting in inhibition of excitation-contraction coupling and subsequent contraction

INDICATION/S

rapangilinan — 2021-09-13 09:23:51 UTC

Alone or with other agents in the management of hypertension, angina pectoris, and vasospastic (Prinzmetal’s) angina

CONTRAINDICATIONS

rapangilinan — 2021-09-13 09:30:27 UTC

Hypersensitivity
Systolic blood pressure <90 mm Hg.
Severe hepatic impairment
History of CHF
Aortic stenosis

rapangilinan — 2021-09-13 09:31:59 UTC

CNS: headache, dizziness, fatigue

CV: peripheral edema, bradycardia, hypotension, palpitations

GI: gingival hyperplasia, nausea

Derm: flushing

NURSING RESPONSIBILITIES

rapangilinan — 2021-09-13 09:33:49 UTC

Monitor blood pressure and pulse before therapy, during dose titration, and periodically during therapy.
Monitor ECG periodically during prolonged therapy
Monitor weight daily
Monitor I&O
Assess for signs of CHF
Assess location, duration, intensity, and precipitating factors of patient’s anginal pain
Encourage patient to avoid large amounts (6–8 glasses of grapefruit juice/day) during therapy.
Instruct patient to contact health care professional if heart rate is <50 bpm
Caution patient to change positions slowly to minimize orthostatic hypotension.
Instruct patient on concurrent nitrate or beta-blocker therapy to continue taking both medications as directed and to use SL nitroglycerin as needed or prescribed
Encourage patient to avoid driving or other activities requiring alertness until response to the medication is known since this medication may cause drowsiness or dizziness
Encourage patient to contact health care professional if chest pain does not improve or worsens after therapy, if it occurs with diaphoresis, if shortness of breath occurs, or if severe, persistent headache occur
Instruct patient to avoid concurrent use of alcohol or OTC medications, especially cold preparations, without consulting health care professional.

Generic: Metoprolol Tartrate

rapangilinan — 2021-09-13 09:44:11 UTC

Brand: Lopressor
Stock dosage:

PO - 25mg, 50mg, 100mg, 200mg, 450mg
IV: 5mg/5ml

rapangilinan — 2021-09-13 09:45:14 UTC

rapangilinan — 2021-09-13 09:50:21 UTC

rapangilinan — 2021-09-13 09:51:23 UTC

Therapeutic: antianginals, antihypertensives

Pharmacologic: beta blockers

MECHANISM OF ACTION

rapangilinan — 2021-09-13 09:52:13 UTC

Blocks stimulation of β₁ adrenergic receptors but has little or no effect on β₂-receptors except in high doses

INDICATION/s

rapangilinan — 2021-09-13 09:53:31 UTC

Hypertension
Angina pectoris
Prevention of MI and decreased mortality in patients with recent MI
Management of stable, symptomatic (class II or III) heart failure due to ischemic, hypertensive or cardiomyopathic origin

CONTRAINDICATIONS

rapangilinan — 2021-09-13 09:54:20 UTC

Decompensated CHF
Pulmonary edema
Cardiogenic shock
Bradycardia or heart block

rapangilinan — 2021-09-13 09:57:11 UTC

CNS: fatigue, weakness, anxiety, drowsiness, insomnia, mental status changes

EENT: blurred vision, stuffy nose

RESPIRATORY: bronchospasm, wheezing

CV: bradycardia, hypotension, peripheral vasoconstriction

GI: constipation, diarrhea, dry mouth, gastric pain, heartburn

GU: erectile dysfunction, decrease libido, urinary frequency

NURSING RESPONSIBILITIES

rapangilinan — 2021-09-13 10:00:14 UTC

Monitor vital signs and ECG every 5–15 min during and for several hours after parenteral administration. If heart rate <40 bpm, especially if cardiac output is also decreased, administer atropine 0.25–0.5 mg IV as ordered
Monitor weight daily
Monitor I & O
Assess frequency and characteristics of anginal attacks periodically during therapy
Provide health education that this medication should be taken with meals or directly after eating
Caution patient to avoid driving or other activities that require alertness until response to the drug is known as this may cause drowsiness
Advise patient to change positions slowly to minimize orthostatic hypotension.
Caution patient that this medication may increase sensitivity to cold.
Instruct patient to consult health care professional before taking other Rx, OTC, or herbal products, especially cold preparations, concurrently with this medication. Patients on antihypertensive therapy should also avoid excessive amounts of caffeinated coffee, tea, and cola