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      <title>Type 3 Immune Complex-Mediated Hypersensitivity: Poststreptococcal Glomerulonephritis         by Jessica Bunker</title>
      <link>https://padlet.com/jbunk9538_/rn75cr9e8ou5fvhf</link>
      <description>Breakdown of body&#39;s hypersensitivity response after a bacterial infection</description>
      <language>en-us</language>
      <pubDate>2023-10-09 19:15:12 UTC</pubDate>
      <lastBuildDate>2023-10-16 01:46:01 UTC</lastBuildDate>
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      <item>
         <title>Overview</title>
         <author>jbunk9538_</author>
         <link>https://padlet.com/jbunk9538_/rn75cr9e8ou5fvhf/wish/2738693703</link>
         <description><![CDATA[]]></description>
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         <pubDate>2023-10-09 19:32:52 UTC</pubDate>
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         <title>Risk Factors</title>
         <author>jbunk9538_</author>
         <link>https://padlet.com/jbunk9538_/rn75cr9e8ou5fvhf/wish/2738703486</link>
         <description><![CDATA[<div>*Recent bacterial infection (Group A strep infection of throat or skin)<br>*Age 5-12 are most susceptible<br>*Uninsured individuals who are not as likely to seek treatment for initial strep infection.</div>]]></description>
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         <pubDate>2023-10-09 19:42:21 UTC</pubDate>
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         <title>Clinical Manifestations</title>
         <author>jbunk9538_</author>
         <link>https://padlet.com/jbunk9538_/rn75cr9e8ou5fvhf/wish/2738715400</link>
         <description><![CDATA[<div>HAD STREP acronym to remember clinical signs and symptoms<br><br><strong>H</strong>-hypertension (due to renal impairment)<br><strong>A</strong>-anti streptolysin titer (will be positive)<br><strong>D</strong>-decreased GFR (low urine output)<br><strong>S</strong>-swelling (face &amp; eyes, mostly in morning)<br><strong>T</strong>-tea or cola colored urine (hematuria)<br><strong>R</strong>-recent strep infection<br><strong>E</strong>-elevated BUN/creatinine (low urine flow)<br><strong>P</strong>- proteinuria (inflammation in kidneys)</div>]]></description>
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         <pubDate>2023-10-09 19:53:14 UTC</pubDate>
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      <item>
         <title>What is a type III hypersensitivity?</title>
         <author>jbunk9538_</author>
         <link>https://padlet.com/jbunk9538_/rn75cr9e8ou5fvhf/wish/2738718910</link>
         <description><![CDATA[<div>Post Streptococcal Glomerulonephritis conforms to the typical presentation of a type III hypersensitivity reaction in that antigen-antibody complexes are deposited in the glomeruli of the kidneys causing inflammation, pain, swelling and fever.&nbsp;In addition, blood serum levels of patients with the condition show aggressive activation of the complement system, another hallmark of a type III hypersensitivity. </div>]]></description>
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         <pubDate>2023-10-09 19:56:13 UTC</pubDate>
         <guid>https://padlet.com/jbunk9538_/rn75cr9e8ou5fvhf/wish/2738718910</guid>
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         <title>Cellular/Organ Level Pathophysiology</title>
         <author>jbunk9538_</author>
         <link>https://padlet.com/jbunk9538_/rn75cr9e8ou5fvhf/wish/2742214657</link>
         <description><![CDATA[<div>The underlying pathophysiologic mechanism for poststreptococcal glomerulonephritis is inflammation causing tissue destruction. Nephritis associated plasmin receptors bind to glomeruli and damage the basement membrane. These receptors are produced as an immune response following a streptococcal infection.</div>]]></description>
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         <pubDate>2023-10-11 17:24:42 UTC</pubDate>
         <guid>https://padlet.com/jbunk9538_/rn75cr9e8ou5fvhf/wish/2742214657</guid>
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         <title>Therapeutic Management</title>
         <author>jbunk9538_</author>
         <link>https://padlet.com/jbunk9538_/rn75cr9e8ou5fvhf/wish/2745650306</link>
         <description><![CDATA[<div>-Management of swelling and hypertension<br>*Low sodium/potassium diet<br>*Restricted fluid intake<br>*Increased calcium in diet (prevents&nbsp; &nbsp; &nbsp; kidney stone formation)<br>*Decrease protein intake<br>*Use of diuretic medication<br><br>-Treatment of lingering streptococcal infection<br>*Penicillin&nbsp;</div>]]></description>
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         <pubDate>2023-10-13 19:51:22 UTC</pubDate>
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         <title>Additional Background Information from the CDC</title>
         <author></author>
         <link>https://padlet.com/jbunk9538_/rn75cr9e8ou5fvhf/wish/2747129847</link>
         <description><![CDATA[]]></description>
         <enclosure url="https://www.cdc.gov/groupastrep/diseases-public/post-streptococcal.html#:~:text=Post%2DStreptococcal%20Glomerulonephritis%3A%20All%20You%20Need%20to%20Know&amp;text=Post%2Dstreptococcal%20glomerulonephritis%20(gloe%2D,prevent%20group%20A%20strep%20infections." />
         <pubDate>2023-10-15 23:10:42 UTC</pubDate>
         <guid>https://padlet.com/jbunk9538_/rn75cr9e8ou5fvhf/wish/2747129847</guid>
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