https://padlet.com/kmcoxen19/r8zxc37tgmkc en-us 2017-04-10 16:35:08 UTC 2017-04-11 16:26:16 UTC hello@padlet.com kmcoxen19 https://padlet.com/kmcoxen19/r8zxc37tgmkc/wish/165720473 https://speakingofresearch.com/facts/medical-benefits/]]> 2017-04-10 16:36:31 UTC https://padlet.com/kmcoxen19/r8zxc37tgmkc/wish/165720473 kmcoxen19 https://padlet.com/kmcoxen19/r8zxc37tgmkc/wish/165720532 Americans are living longer, healthier lives, therefore we need to test on dogs before humans.]]> 2017-04-10 16:36:42 UTC https://padlet.com/kmcoxen19/r8zxc37tgmkc/wish/165720532 kmcoxen19 https://padlet.com/kmcoxen19/r8zxc37tgmkc/wish/165720565 The amount of penicillin needed to treat a human is 3,000 times greater than for a mouse. Without these early whole animal proofs on toxicity and effectiveness, penicillin would not have been developed further. Therefor, no humans would ever have been able to use Penicillin.]]> 2017-04-10 16:36:51 UTC https://padlet.com/kmcoxen19/r8zxc37tgmkc/wish/165720565 kmcoxen19 https://padlet.com/kmcoxen19/r8zxc37tgmkc/wish/165720570 Two doctors established a blood transfusion in animals. Leading them to believe that it would work in humans as well.]]> 2017-04-10 16:36:54 UTC https://padlet.com/kmcoxen19/r8zxc37tgmkc/wish/165720570 kmcoxen19 https://padlet.com/kmcoxen19/r8zxc37tgmkc/wish/165720573 If we didn't have animals then vaccines would never have been found.]]> 2017-04-10 16:36:54 UTC https://padlet.com/kmcoxen19/r8zxc37tgmkc/wish/165720573 kmcoxen19 https://padlet.com/kmcoxen19/r8zxc37tgmkc/wish/165720594 "Surgical techniques for transplantation were perfected in dogs and pigs in the 1950s and became routine in humans. Among the scientists involved in this effort was Joseph E. Murray, who was subsequently awarded the Nobel prize in recognition of this and other work. However, rejection remained a problem. Cyclosporine, which is extracted from a species of fungus, was discovered in 1972 and found to be a potent immune suppressor in mice. Tests in humans found that it prolonged the survival of grafted kidneys. Research on transplants in dogs showed that combining cyclosporine with steroid produces a three-fold increase in survival time."]]> 2017-04-10 16:36:59 UTC https://padlet.com/kmcoxen19/r8zxc37tgmkc/wish/165720594 kmcoxen19 https://padlet.com/kmcoxen19/r8zxc37tgmkc/wish/165720599 "The initial use of animals here has now meant an alternative to animals for breast cancer research. Tamoxifen work showed that lab grown cultures of human tumor cells will respond to drugs that are effective in patients. Without animal work it may not have been possible to show that the cell culture results were relevant and reliable. Animal studies, mainly rats and mice, have also been crucial in the development of monoclonal antibody treatments such as Herceptin."]]> 2017-04-10 16:37:00 UTC https://padlet.com/kmcoxen19/r8zxc37tgmkc/wish/165720599 kmcoxen19 https://padlet.com/kmcoxen19/r8zxc37tgmkc/wish/165720602 "Experimental surgery in monkeys identified the subthalamic nucleus as a target for treatment of Parkinson’s. Subsequently Parkinson’s was induced in macaque monkeys and then controlled by means of an electrode to the subthalamic nucleus, the brain centre responsible for the disease. Prof. Tipu Aziz of Oxford University applied the same techniques to his human patients, fitting an electrode to their subthalamic nucleus, and switching off their tremor."]]> 2017-04-10 16:37:01 UTC https://padlet.com/kmcoxen19/r8zxc37tgmkc/wish/165720602 kmcoxen19 https://padlet.com/kmcoxen19/r8zxc37tgmkc/wish/165720607 "In a series of classic experiments, during the summer of 1921, Canadian doctor Frederick Banting, along with student Charles Best, managed to extract insulin. They injected their extract into a diabetic dog, close to death, restoring it to health. But their extract caused high fever in patients. Biochemist James Collip then developed a purification method but the only way to check whether insulin was present and in what amount, was to measure its ability to lower blood sugar in rabbits. Since insulin overdose is fatal, this was essential. These extracts were first used in dogs, then in patients in 1922."]]> 2017-04-10 16:37:02 UTC https://padlet.com/kmcoxen19/r8zxc37tgmkc/wish/165720607 kmcoxen19 https://padlet.com/kmcoxen19/r8zxc37tgmkc/wish/165720618 Work on dogs, particularly dachshunds who are prone to spinal injury a has prompted human clinical trials for spinal injury.]]> 2017-04-10 16:37:03 UTC https://padlet.com/kmcoxen19/r8zxc37tgmkc/wish/165720618 kmcoxen19 https://padlet.com/kmcoxen19/r8zxc37tgmkc/wish/165720714 " While there have been remarkable improvements
in the human environment, animal research has played a major part in
developing improvements in human health. Animal research advanced the treatment of infections, helped with immunisation, improved cancer
treatment and has had a major impact on managing heart disease, brain disorders, arthritis and transplantation. "]]> 2017-04-10 16:37:27 UTC https://padlet.com/kmcoxen19/r8zxc37tgmkc/wish/165720714