Autoimmune Encephalitis by Monica Rains https://padlet.com/mrains01/AutoimmuneEncephalitis A group of conditions characterized by brain inflammation that causes various psychiatric and neurological symptoms en-us 2019-03-26 23:39:37 UTC 2026-03-17 21:13:09 UTC hello@padlet.com http://www.ajnr.org/content/ajnr/38/6/1070/F7.large.jpg Brain on Fire:Netflix Film mrains01 https://padlet.com/mrains01/AutoimmuneEncephalitis/wish/345497796 The New York Times bestselling book was recently turned into a Netflix film. Check out the trailer!]]> 2019-03-26 23:51:54 UTC https://padlet.com/mrains01/AutoimmuneEncephalitis/wish/345497796 Brain on Fire by Susannah Cahalan mrains01 https://padlet.com/mrains01/AutoimmuneEncephalitis/wish/345499120 In her autobiography Susannah Cahalan, details her first hand experience with Autoimmune Encephalitis. She was finally diagnosed with anti-NMDA receptor encephalitis after a month of violent episodes and delusions in the hospital. Many with this disease suffer from misdiagnosis for much longer. Her book is a detailed account of her recovery process.]]> 2019-03-26 23:59:48 UTC https://padlet.com/mrains01/AutoimmuneEncephalitis/wish/345499120 Antibodies in AE can attack various antigen targets: mrains01 https://padlet.com/mrains01/AutoimmuneEncephalitis/wish/345502785
  • NMDA, AMPA, GABA, Glycine,  and Dopamine-2,  receptors
  • LGI1, Caspr2, DPPX, mGluR5, mGluR1, Amphiphysin, GAD
    • These antigen targets are cell-surface or synaptic proteins found in the brain and spinal cord.
    ]]>     2019-03-27 00:20:40 UTC https://padlet.com/mrains01/AutoimmuneEncephalitis/wish/345502785     mrains01 https://padlet.com/mrains01/AutoimmuneEncephalitis/wish/345523094 2019-03-27 01:59:49 UTC https://padlet.com/mrains01/AutoimmuneEncephalitis/wish/345523094 Go to aealliance.org for additional resources and information about AE mrains01 https://padlet.com/mrains01/AutoimmuneEncephalitis/wish/345525528 2019-03-27 02:16:53 UTC https://padlet.com/mrains01/AutoimmuneEncephalitis/wish/345525528 World Encephalitis Day 2019 Video mrains01 https://padlet.com/mrains01/AutoimmuneEncephalitis/wish/345526318 View the video below for several personal accounts of this disease, information from encephalitis specialists, and a call for increased awareness.]]> 2019-03-27 02:22:48 UTC https://padlet.com/mrains01/AutoimmuneEncephalitis/wish/345526318 Summary of AE and Sources Used throughout this Padlet mrains01 https://padlet.com/mrains01/AutoimmuneEncephalitis/wish/345534232 2019-03-27 03:19:59 UTC https://padlet.com/mrains01/AutoimmuneEncephalitis/wish/345534232 Treatment of AE mrains01 https://padlet.com/mrains01/AutoimmuneEncephalitis/wish/345534894 First line therapies:
    • tumor (if present) removal
    • steroid treatment
    • IVIG (intravenous immunoglobulin) therapy to prevent antibody binding
    • plasmapheresis to filter out antibodies from the blood
    If the above therapies do not improve symptoms some "second-line" treatments are used:
    • Rituximab
    • CellCept
    • Cytoxan
    These drugs heavily suppress the immune system response.

    Sources: 
    ]]>     2019-03-27 03:25:15 UTC https://padlet.com/mrains01/AutoimmuneEncephalitis/wish/345534894     Early Diagnosis and Treatment can lead to full recovery mrains01 https://padlet.com/mrains01/AutoimmuneEncephalitis/wish/345536493 7 patients presenting with AE in this study were promptly diagnosed with specific subsets of AE. Their prompt diagnosis and treatment led to largely successful recoveries. Interestingly, most patients with AE have complete loss of memory from the worst weeks of their time with the disease.]]> 2019-03-27 03:36:09 UTC https://padlet.com/mrains01/AutoimmuneEncephalitis/wish/345536493 AE in other mammals mrains01 https://padlet.com/mrains01/AutoimmuneEncephalitis/wish/345539930 In 2015 the death of a world famous polar bear, Knut from the Berlin Zoo, was attributed to anti-NMDAR AE. This case suggests that this disease is not specific to only humans but occurs in other mammals. While encephalitis has been found to occur in animals and can be treated, autoimmune encephalitis is a relatively new finding that constitutes alternative treatments.]]> 2019-03-27 03:55:39 UTC https://padlet.com/mrains01/AutoimmuneEncephalitis/wish/345539930