Discussion Board- Unit 2 by https://padlet.com/briannasalas2/q3q23o3uz773d2b1 Pharmacology en-us 2023-06-22 22:51:45 UTC 2023-06-23 01:29:26 UTC hello@padlet.com Sympathetic Nervous System (SNS) briannasalas2 https://padlet.com/briannasalas2/q3q23o3uz773d2b1/wish/2630443876 AKA: "fight or flight" system]]> 2023-06-22 22:55:33 UTC https://padlet.com/briannasalas2/q3q23o3uz773d2b1/wish/2630443876 Parasympathetic Nervous System (PSNS) briannasalas2 https://padlet.com/briannasalas2/q3q23o3uz773d2b1/wish/2630444352 AKA: "rest and digest" system]]> 2023-06-22 22:56:31 UTC https://padlet.com/briannasalas2/q3q23o3uz773d2b1/wish/2630444352 Pre vs. Post ganglions of SNS & PSNS briannasalas2 https://padlet.com/briannasalas2/q3q23o3uz773d2b1/wish/2630450943 2023-06-22 23:12:09 UTC https://padlet.com/briannasalas2/q3q23o3uz773d2b1/wish/2630450943 briannasalas2 https://padlet.com/briannasalas2/q3q23o3uz773d2b1/wish/2630457130 Hitner, H. (2022). Pharmacology an introduction. McGraw-HillEducation. ]]> 2023-06-22 23:26:33 UTC https://padlet.com/briannasalas2/q3q23o3uz773d2b1/wish/2630457130 SNS -> NE & Epi briannasalas2 https://padlet.com/briannasalas2/q3q23o3uz773d2b1/wish/2630464748 Sympathetic Nervous System releases Norepinephrine (NE) & Epinephrine (Epi)]]> 2023-06-22 23:41:49 UTC https://padlet.com/briannasalas2/q3q23o3uz773d2b1/wish/2630464748 PSNS -> ACh briannasalas2 https://padlet.com/briannasalas2/q3q23o3uz773d2b1/wish/2630465574 Parasympathetic Nervous System releases Acetylcholine (ACh)]]> 2023-06-22 23:43:16 UTC https://padlet.com/briannasalas2/q3q23o3uz773d2b1/wish/2630465574 SNS -> Adrenergic Receptors briannasalas2 https://padlet.com/briannasalas2/q3q23o3uz773d2b1/wish/2630470254 Adrenergic Receptors include:
1) Alpha Receptors
     a) Alpha-1 Receptors
        - location: most arteries & veins; iris muscle (eye)
    b) Alpha-2 Receptors
        - location: adrenergic nerve ending
2) Beta Receptors
     a) Beta-1 Receptors
        - location: heart
    b) Beta-2 Receptors
        - location: bronchiolar (smooth muscle); uterus; coronary & skeletal muscle + blood vessels]]> 2023-06-22 23:50:55 UTC https://padlet.com/briannasalas2/q3q23o3uz773d2b1/wish/2630470254 PSNS -> Cholinergic Receptors briannasalas2 https://padlet.com/briannasalas2/q3q23o3uz773d2b1/wish/2630479432 Cholinergic Receptors include:
1) Muscarinic Receptors
- location: cell membranes of visceral organs & glands
2) Nicotinic Receptors
     a) Nicotinic-nerve (Nn) Receptors
        - location: PSNS & SNS ganglia
    b) Nicotinic-muscle (Nm) Receptors
        - location: cell membranes of skeletal muscle]]> 2023-06-23 00:04:24 UTC https://padlet.com/briannasalas2/q3q23o3uz773d2b1/wish/2630479432 Alpha & Beta Receptors briannasalas2 https://padlet.com/briannasalas2/q3q23o3uz773d2b1/wish/2630489868 2023-06-23 00:17:59 UTC https://padlet.com/briannasalas2/q3q23o3uz773d2b1/wish/2630489868 Alpha-2 Receptor -> Decrease Release of NE briannasalas2 https://padlet.com/briannasalas2/q3q23o3uz773d2b1/wish/2630495404 Organ + Response:
- Adrenergic Nerve Ending => (Epi & NE) Decrease Release of NE]]> 2023-06-23 00:24:22 UTC https://padlet.com/briannasalas2/q3q23o3uz773d2b1/wish/2630495404 Alpha-1 Receptor -> Contraction of Smooth Muscle briannasalas2 https://padlet.com/briannasalas2/q3q23o3uz773d2b1/wish/2630496232 Organ + Response:
- Arteries & Veins => (Epi & NE) Vasoconstriction
- Iris Muscle => (Epi & NE) Pupil Dilation]]> 2023-06-23 00:25:10 UTC https://padlet.com/briannasalas2/q3q23o3uz773d2b1/wish/2630496232 Beta-2 Receptor -> Relaxation of Smooth Muscle briannasalas2 https://padlet.com/briannasalas2/q3q23o3uz773d2b1/wish/2630498596 Organ + Response:
- Bronchiolar Smooth Muscle => (Epi) Bronchodilation
- Uterus => (Epi) Relaxation of Uterus
- Coronary & Skeletal Muscle + Blood Vessels => (Epi) Vasodilation]]> 2023-06-23 00:27:06 UTC https://padlet.com/briannasalas2/q3q23o3uz773d2b1/wish/2630498596 Beta-1 Receptor -> Stimulation of Cardiac Muscle briannasalas2 https://padlet.com/briannasalas2/q3q23o3uz773d2b1/wish/2630498729 Organ + Response:
- Heart => (EPI) greater increase in HR, FOC, & atrioventricular conduction; (NE) moderate increase in HR, FOC, & atrioventricular conduction]]> 2023-06-23 00:27:14 UTC https://padlet.com/briannasalas2/q3q23o3uz773d2b1/wish/2630498729 Muscarinic Receptor-> +GI & -HR briannasalas2 https://padlet.com/briannasalas2/q3q23o3uz773d2b1/wish/2630511919 Organ + Response:
- GI Tract => increased GI motility & secretion
- Heart => decrease HR]]> 2023-06-23 00:40:16 UTC https://padlet.com/briannasalas2/q3q23o3uz773d2b1/wish/2630511919 Nicotinic-Neural (Nn) Receptor -> ACh released from preganglionic nerve endings briannasalas2 https://padlet.com/briannasalas2/q3q23o3uz773d2b1/wish/2630517033 Organ + Response:
- Autonomic Ganglia => Depolarization (leading to post ganglionic impulse)]]> 2023-06-23 00:45:04 UTC https://padlet.com/briannasalas2/q3q23o3uz773d2b1/wish/2630517033 Nicotinic-Muscle (Nm) Receptor -> ACh released from somatic nerve ending to contract skeletal muscle briannasalas2 https://padlet.com/briannasalas2/q3q23o3uz773d2b1/wish/2630517398 Organ + Response:
- Skeletal Muscle => contraction of sk. muscle]]> 2023-06-23 00:45:29 UTC https://padlet.com/briannasalas2/q3q23o3uz773d2b1/wish/2630517398 Adrenergic Receptors -> Sympathomimetic & Sympatholytic briannasalas2 https://padlet.com/briannasalas2/q3q23o3uz773d2b1/wish/2630537487 Sympathomimetic:
>> Alpha-Adrenergic Drugs -> contract smooth muscle
>> Nonselective Beta-Adrenergic Drugs -> stimulate the heart &relax smooth muscle
>> Selective Beta-2 Adrenergic Drugs -> bronchodilators

Sympatholytic:
>>  Alpha-Adrenergic Blockers -> block alpha effects of NE & EPI
>> Nonselective Beta-Adrenergic Blockers -> block beta-1 & beta-2 effects of EPI
>> Selective Beta-1 Adrenergic Blockers -> block only beta-1 receptors
>> Adrenergic Neuronal Blockers -> reduce NE]]> 2023-06-23 01:09:17 UTC https://padlet.com/briannasalas2/q3q23o3uz773d2b1/wish/2630537487 Adrenergic Drugs & Effects briannasalas2 https://padlet.com/briannasalas2/q3q23o3uz773d2b1/wish/2630539153 2023-06-23 01:11:01 UTC https://padlet.com/briannasalas2/q3q23o3uz773d2b1/wish/2630539153 Cholinergic Drugs -> Direct-Acting & Indirect-Acting briannasalas2 https://padlet.com/briannasalas2/q3q23o3uz773d2b1/wish/2630545396 Direct-Acting Cholinergic Drugs:
bind to muscarinic receptors; increase GI secretion & motility, increase urinary tract function, pupil constriction, decrease HR, bronchoconstriction

Indirect-Acting Cholinergic Drugs:
inhibit acetylcholinesterase (allows accumulation of ACh at cholinergic receptor sites)]]> 2023-06-23 01:17:38 UTC https://padlet.com/briannasalas2/q3q23o3uz773d2b1/wish/2630545396 Atropine briannasalas2 https://padlet.com/briannasalas2/q3q23o3uz773d2b1/wish/2630549717 Antidote for cholinesterase]]> 2023-06-23 01:21:50 UTC https://padlet.com/briannasalas2/q3q23o3uz773d2b1/wish/2630549717 Flavoxate briannasalas2 https://padlet.com/briannasalas2/q3q23o3uz773d2b1/wish/2630550246 Relief of urinary spasms, urgency, incontinence]]> 2023-06-23 01:22:22 UTC https://padlet.com/briannasalas2/q3q23o3uz773d2b1/wish/2630550246 Ipratropium briannasalas2 https://padlet.com/briannasalas2/q3q23o3uz773d2b1/wish/2630550633 Bronchodilation, asthma, COPD]]> 2023-06-23 01:22:47 UTC https://padlet.com/briannasalas2/q3q23o3uz773d2b1/wish/2630550633 Phenylephrine briannasalas2 https://padlet.com/briannasalas2/q3q23o3uz773d2b1/wish/2630551310 Nasal decongestant
Increase blood pressure]]> 2023-06-23 01:23:29 UTC https://padlet.com/briannasalas2/q3q23o3uz773d2b1/wish/2630551310 Midodrine briannasalas2 https://padlet.com/briannasalas2/q3q23o3uz773d2b1/wish/2630551919 Increase blood pressure]]> 2023-06-23 01:24:07 UTC https://padlet.com/briannasalas2/q3q23o3uz773d2b1/wish/2630551919 Oxymetazoline briannasalas2 https://padlet.com/briannasalas2/q3q23o3uz773d2b1/wish/2630552397 Nasal decongestant]]> 2023-06-23 01:24:35 UTC https://padlet.com/briannasalas2/q3q23o3uz773d2b1/wish/2630552397 Tetrahydrozoline briannasalas2 https://padlet.com/briannasalas2/q3q23o3uz773d2b1/wish/2630552915 Nasal decongestant
Ocular decongestant]]> 2023-06-23 01:25:07 UTC https://padlet.com/briannasalas2/q3q23o3uz773d2b1/wish/2630552915 POSTgangalionic Nerve Fiber in SNS -> NE & Epi briannasalas2 https://padlet.com/briannasalas2/q3q23o3uz773d2b1/wish/2630555968 2023-06-23 01:28:14 UTC https://padlet.com/briannasalas2/q3q23o3uz773d2b1/wish/2630555968 POSTganglionic Nerve Fiber in PSNS -> ACh briannasalas2 https://padlet.com/briannasalas2/q3q23o3uz773d2b1/wish/2630556347 2023-06-23 01:28:39 UTC https://padlet.com/briannasalas2/q3q23o3uz773d2b1/wish/2630556347 PREganglionic Nerve Fiber in SNS & PSNS -> ACh briannasalas2 https://padlet.com/briannasalas2/q3q23o3uz773d2b1/wish/2630556743 2023-06-23 01:29:07 UTC https://padlet.com/briannasalas2/q3q23o3uz773d2b1/wish/2630556743