Dermatomyositis (DM) by YADRIELA ALEXANDRA COLON GONZALEZ https://padlet.com/yadrielacolon/pzms9lwkg5pjp66t en-us 2024-05-22 13:16:21 UTC 2024-05-23 21:32:42 UTC hello@padlet.com https://padlet-uploads.storage.googleapis.com/2499657771/c989a5fea614cf2bbb3c0b7bb9ceeb8c/Screen_Shot_2024_05_22_at_7_33_07_AM.png Team Members yadrielacolon https://padlet.com/yadrielacolon/pzms9lwkg5pjp66t/wish/3003391792 2024-05-22 13:38:05 UTC https://padlet.com/yadrielacolon/pzms9lwkg5pjp66t/wish/3003391792 Treatment karinaroman2_1 https://padlet.com/yadrielacolon/pzms9lwkg5pjp66t/wish/3003650411 2024-05-22 17:18:04 UTC https://padlet.com/yadrielacolon/pzms9lwkg5pjp66t/wish/3003650411 Case Report arianasanmiguel22 https://padlet.com/yadrielacolon/pzms9lwkg5pjp66t/wish/3003870600 2024-05-22 20:40:08 UTC https://padlet.com/yadrielacolon/pzms9lwkg5pjp66t/wish/3003870600 Clinical Presentation yadrielacolon https://padlet.com/yadrielacolon/pzms9lwkg5pjp66t/wish/3003982932 2024-05-22 23:56:30 UTC https://padlet.com/yadrielacolon/pzms9lwkg5pjp66t/wish/3003982932 yadrielacolon https://padlet.com/yadrielacolon/pzms9lwkg5pjp66t/wish/3003986361 2024-05-22 23:59:50 UTC https://padlet.com/yadrielacolon/pzms9lwkg5pjp66t/wish/3003986361 arianasanmiguel22 https://padlet.com/yadrielacolon/pzms9lwkg5pjp66t/wish/3004109519 2024-05-23 01:20:42 UTC https://padlet.com/yadrielacolon/pzms9lwkg5pjp66t/wish/3004109519 Diagnosis paolaboneshuertas https://padlet.com/yadrielacolon/pzms9lwkg5pjp66t/wish/3004211508 2024-05-23 02:19:32 UTC https://padlet.com/yadrielacolon/pzms9lwkg5pjp66t/wish/3004211508 Pathophysiology oscararevalo4 https://padlet.com/yadrielacolon/pzms9lwkg5pjp66t/wish/3005472109 Specific pathophysiology is not known yet; however, it is thought that the cascade of clinical effects for this autoimmune inflammatory disease affecting the perifascicular region of skeletal muscles is driven by anti-Mi2, anti-Jo1, and anti-P155/P140 antibodies.

Clinical manifestations:

Anti-Mi2 antibodies (Gottron papules, and heliotrope rash).

Anti-Jo1 antibodies (mechanic’s hands).

Anti-P155/P140 antibodies (paraneoplastic and juvenile DM).

]]> 2024-05-23 21:13:07 UTC https://padlet.com/yadrielacolon/pzms9lwkg5pjp66t/wish/3005472109 References: oscararevalo4 https://padlet.com/yadrielacolon/pzms9lwkg5pjp66t/wish/3005473532 Dalakas MC. Mechanisms of disease: signaling pathways and immunobiology of inflammatory myopathies. Nat Clin Pract Rheumatol. 2006 Apr;2(4):219-27. doi: 10.1038/ncprheum0140.

]]> 2024-05-23 21:16:31 UTC https://padlet.com/yadrielacolon/pzms9lwkg5pjp66t/wish/3005473532