From the 13th century to the advent of the railway in the early 20th century, Safranbolu was an important caravan station on the main East–West trade route. The Old Mosque, Old Bath and Süleyman Pasha Medrese were built in 1322. During its apogee in the 17th century, Safranbolu's architecture influenced urban development throughout much of the Ottoman Empire.

Located in southwestern Turkey, in the upper valley of the Morsynus River, the site consists of two components: the archaeological site of Aphrodisias and the marble quarries northeast of the city. The temple of Aphrodite dates from the 3rd century BC and the city was built one century later. The wealth of Aphrodisias came from the marble quarries and the art produced by its sculptors. The city streets are arranged around several large civic structures, which include temples, a theatre, an agora and two bath complexes.

In a spectacular landscape, entirely sculpted by erosion, the Göreme valley and its surroundings contain rock-hewn sanctuaries that provide unique evidence of Byzantine art in the post-Iconoclastic period. Dwellings, troglodyte villages and underground towns – the remains of a traditional human habitat dating back to the 4th century – can also be seen there.

Deriving from springs in a cliff almost 200 m high overlooking the plain, calcite-laden waters have created at Pamukkale (Cotton Palace) an unreal landscape, made up of mineral forests, petrified waterfalls and a series of terraced basins. At the end of the 2nd century B.C. the dynasty of the Attalids, the kings of Pergamon, established the thermal spa of Hierapolis. The ruins of the baths, temples and other Greek monuments can be seen at the site.

The archaeological site of Hattusha, former capital of the Hittite Empire, is notable for its urban organization, the types of construction that have been preserved (temples, royal residences, fortifications), the rich ornamentation of the Lions' Gate and the Royal Gate, and the ensemble of rock art at Yazilikaya. The city enjoyed considerable influence in Anatolia and northern Syria in the 2nd millennium B.C.