Discussion Board Unit 2 by Isabel Figueroa https://padlet.com/isabelfigueroa6/ppnfarz4hxtd6sdf The Automatic Nervous System and its two divisions en-us 2021-09-25 20:42:00 UTC 2021-09-26 00:41:46 UTC hello@padlet.com Neurotransmitter: Acetylcholine (ACH) isabelfigueroa6 https://padlet.com/isabelfigueroa6/ppnfarz4hxtd6sdf/wish/1767820064 - Released at the ganglia and the postganglionic nerve endings.
- Cholinergic receptors: act in the cardiac and smooth muscle membrane sites.]]> 2021-09-25 21:42:16 UTC https://padlet.com/isabelfigueroa6/ppnfarz4hxtd6sdf/wish/1767820064 Neurotransmitter: ACH and Norepinephrine (NE) isabelfigueroa6 https://padlet.com/isabelfigueroa6/ppnfarz4hxtd6sdf/wish/1767825602 - ACH released at the ganglia and NE released at the postganglionic nerve endings.
- Adrenergic receptors: act in the cardiac and smooth muscle membrane sites.]]> 2021-09-25 21:50:03 UTC https://padlet.com/isabelfigueroa6/ppnfarz4hxtd6sdf/wish/1767825602 End Organ Response: isabelfigueroa6 https://padlet.com/isabelfigueroa6/ppnfarz4hxtd6sdf/wish/1767859140 Eye
- constricts pupil

Lacrimal Gland
- Produce tears

Mouth
- Parotid gland and Salivary gland: produce saliva

Bronchi
- constricts

Heart
- decreases heart rate

Stomach:
- digestion

Intestines/ GI motility/ secretions:
- Increased

Urinary Bladder:
- contraction

Urinary Sphincter:
- Relaxation]]> 2021-09-25 22:40:54 UTC https://padlet.com/isabelfigueroa6/ppnfarz4hxtd6sdf/wish/1767859140 End Organ Response: isabelfigueroa6 https://padlet.com/isabelfigueroa6/ppnfarz4hxtd6sdf/wish/1767863983 Eye
- dilates pupil

Adrenal Medulla
- Release of epinephrine

Arteries
- Vasoconstriction

Bronchi
- relaxes

Heart
- Increase heart rate

Intestines/ GI motility/ Secretion
- decreased

Urinary Bladder
- relaxation

Urinary Sphincter
- contraction

]]> 2021-09-25 22:49:07 UTC https://padlet.com/isabelfigueroa6/ppnfarz4hxtd6sdf/wish/1767863983 Drug Class isabelfigueroa6 https://padlet.com/isabelfigueroa6/ppnfarz4hxtd6sdf/wish/1767912169 Parasympathomimetic:
- Receptor: cholinergic (muscarinic)
- Agonist
- direct or in-direct
- direct acting drugs bind to muscarine receptors, producing effects similar to those of ACH

Drug examples:
 direct
Acetylcholine (Miochol-E)
Bethanechol (Urecholine)
Carbachol (Isopto carbachol)
Pilocarpine (Isopto carpine)
indirect
Ambenonium (Mytelase)
Demecarium (Humorsol)
Echothiophate (Phospholine)
Edrophonium (Tensilon)
Neostigmine (Prostigmin)
Physostigmine (generic)
Pyridostigmine (Mestinon)
Donepezil (Aricept)
Galantamine (Razadyne)
Rivastigmine (Exelon)

Parasympholytic:
- Receptor: Muscarinic
- Antagonist
- Bind to muscarinic receptor, acting as an antagonist competitive of ACH.

Drug examples:
Atropine (generic)
Atropine (Isopto atropine)
Darifenacin (Enablex)
Dicyclomine (Bentyl)
Flavoxate (Urispas)
Glycopyrrolate (Robinul)
Hyoscyamine (Anaspaz)
Ipratropium (Atrovent)
Methscopolamine (Pamine)
Oxybutynin (Ditropan, Detropan XL) (Oxytrol, OTC)
Propantheline (Pro-Banthine)
Scopolamine (generic) (Transderm scop)
Solifenacin (Vesicare)
Tiotropium (Spiriva)
Tolterodine (Detrol, Detrol LA)
Trospium (Sanctura)]]> 2021-09-26 00:24:26 UTC https://padlet.com/isabelfigueroa6/ppnfarz4hxtd6sdf/wish/1767912169 Drug Class isabelfigueroa6 https://padlet.com/isabelfigueroa6/ppnfarz4hxtd6sdf/wish/1767919907 Sympathomimetics:
- Receptor: Alpha 1- mediated smooth muscle (vasoconstriction), increased blood pressure
Alpha 2- negative feedback effect to decrease release of NE
Beta 1- cardiac stimulation; increased heart rate and force of contraction
Beta 2- bronchodilation, and increased blood flow to the heart and skeletal muscle
- Agonist

Drug examples:
Metaraminol (Aramine)
Phenylephrine (Neo-synephrine)
Dopamine (Intropin)
Albuterol (Proventil)

Sympatholytic:
- Receptor: Alpha 1- relaxation of alpha-1 mediated smooth muscle (vasodilation), decreased blood pressure
Beta 1- decreased cardiac function; decreased heart rate and force of contraction
Beta 2- beta-2-mediated smooth muscle contraction (nontherapeutic)
Adrenergic nerve endings- Interferes with synthesis and/or release of NE from nerve ending, decreases all sympathetic activity, lowers blood pressure and cardiac function
- Antagonist

Drug examples:
Alfuzosin (Uroxatral)
Doxazosin (Cardura)
Phenoxybenzamine (Dibenzyline)
Prazosin (Minipress)
Silodosin (Rapaflow)
Tamsulosin (Flomax)
Terazosin (Hytrin)
Carvedilol (Coreg)
Acebutolol (Sectral)]]> 2021-09-26 00:40:29 UTC https://padlet.com/isabelfigueroa6/ppnfarz4hxtd6sdf/wish/1767919907 isabelfigueroa6 https://padlet.com/isabelfigueroa6/ppnfarz4hxtd6sdf/wish/1767920440 Pharmacology Textbook: An Introduction
Hitner, Henry; Nagle, Barbara]]> 2021-09-26 00:41:35 UTC https://padlet.com/isabelfigueroa6/ppnfarz4hxtd6sdf/wish/1767920440