Non-Hodgkin's Lymphoma by Bri White https://padlet.com/whitebriannad/ph5hh2z428783lwv It's Causes and Treatments en-us 2021-03-16 17:40:06 UTC 2025-12-07 13:07:13 UTC hello@padlet.com What is Cancer? whitebriannad https://padlet.com/whitebriannad/ph5hh2z428783lwv/wish/1317069983 Cancer is a group of diseases in which mutations cause cells to divide uncontrollably. This can lead to the formation of tumors, which can spread, leading to cancer. ]]> 2021-03-16 17:42:31 UTC https://padlet.com/whitebriannad/ph5hh2z428783lwv/wish/1317069983 What is Non-Hodgkin's Lymphoma? whitebriannad https://padlet.com/whitebriannad/ph5hh2z428783lwv/wish/1317071043 Non-Hodgkin’s Lymphoma (NHL) is a type of cancer that primarily impacts the lymphatic system. It can start in white blood cells, but it also impacts lymph, the spleen, bone marrow, the thymus, tonsils and the digestive tract. Though all ages can be affected, NHL is found primarily older people. ]]> 2021-03-16 17:42:42 UTC https://padlet.com/whitebriannad/ph5hh2z428783lwv/wish/1317071043 Importance of Checkpoints whitebriannad https://padlet.com/whitebriannad/ph5hh2z428783lwv/wish/1317080488 Checkpoints in interphase are vital as they can prevent the formation of tumors. These checkpoints make sure the cell is ready to divide. When there is an error in interphase, the cell either rapidly divides, is not large enough, doesn’t have enough organelles or has accumulated mutations in its DNA. The accumulation of mutations can cause cancer. ]]> 2021-03-16 17:44:16 UTC https://padlet.com/whitebriannad/ph5hh2z428783lwv/wish/1317080488 Mutations in Mitosis whitebriannad https://padlet.com/whitebriannad/ph5hh2z428783lwv/wish/1317082397 If mutations (changes in DNA) occur internally, typically cancer is caused by a mutation in mitosis. Mitosis is the process in which cells undergo to divide. Cell divison is regulated though a seiries of checkpoints during the start of the cell cycle (interphase) including two growth phases and a DNA synthesis phase. If there are mutations in the checkpoints including the tumor suppresor gene, which prevents tumor formation or ocogenes, which promote cell divison, then division is no lonoger regulated and a cancerous tumor could form. ]]> 2021-03-16 17:44:38 UTC https://padlet.com/whitebriannad/ph5hh2z428783lwv/wish/1317082397 Diagnosis whitebriannad https://padlet.com/whitebriannad/ph5hh2z428783lwv/wish/1317090640 NHL can be diagnosed through a series of tests including: 
  • Physical Exams: look for inflamation or lumps
  • Blood Chemisty: anaylyzes electrolyte, LDH, uric acid, blood urea nitrogen, and creatinine levles and liver function values. 
  • CT Scan: produces an X-ray of organ tissue
  • PET Scan: used to find a malignat tumor in the body
  • MRI: takes pitures of areas inside the body
  • Lumbar puncture: collects cerebral fluid for signs of cancer
  • Ultrasound: to find tumors inside of body tissues. 
]]> 2021-03-16 17:45:59 UTC https://padlet.com/whitebriannad/ph5hh2z428783lwv/wish/1317090640 Carcinogens whitebriannad https://padlet.com/whitebriannad/ph5hh2z428783lwv/wish/1317122880 If a mutation occurs due to the envrionment, carcinogens can cause mutations in our DNA which can lead to mutations in mitosis, which lead to tumor formation. Carcinogens, or cancer causing genes, can also cause cancer. ]]> 2021-03-16 17:51:19 UTC https://padlet.com/whitebriannad/ph5hh2z428783lwv/wish/1317122880 How does this relate to Non-Hodgkin's Lymphoma? whitebriannad https://padlet.com/whitebriannad/ph5hh2z428783lwv/wish/1317201388 Because NHL is a cancer, it is important to know why a healthy person can get diagnosed with NHL. Even if you live a healthy lifestyle, mutations during mitosis or interphase can cause tumors to form. This is due to a lack of cell cycel regulation caused by mutaions in interphase. These mutations accumulate and form a tumor in the white blood cells of the lymphatic system, casuing a Non-Hodgkins Lymphoma diagnosis. However, treatment methods try to kill mutated cells or replace mutated cells with healthy cells. ]]> 2021-03-16 18:05:43 UTC https://padlet.com/whitebriannad/ph5hh2z428783lwv/wish/1317201388 whitebriannad https://padlet.com/whitebriannad/ph5hh2z428783lwv/wish/1317232931 2021-03-16 18:11:57 UTC https://padlet.com/whitebriannad/ph5hh2z428783lwv/wish/1317232931 whitebriannad https://padlet.com/whitebriannad/ph5hh2z428783lwv/wish/1317291156 2021-03-16 18:23:20 UTC https://padlet.com/whitebriannad/ph5hh2z428783lwv/wish/1317291156 Works Cited whitebriannad https://padlet.com/whitebriannad/ph5hh2z428783lwv/wish/1317339190 2021-03-16 18:33:06 UTC https://padlet.com/whitebriannad/ph5hh2z428783lwv/wish/1317339190 Treatment whitebriannad https://padlet.com/whitebriannad/ph5hh2z428783lwv/wish/1319057665 Treatment for NHL is determined by evaluating which cells are impacted (B cells or T cell).  Treatment options will also change based on the age of the patient, however, the options are the same. 

Most common treatment methods include: 
  • chemotherapy: stop the growth of cancer cells by killing them or preventing division
  • radiation: uses high energy x-rays to kill cancer cells
  • stem cell transplant: healthy cells are intoduced into the body to replace cancer cells
  • medicines: increases productivity of immune system
  • phototherapy: uses a laser light to kill cancer cells
  • immunotherapy: the patients immune system fights the cancer
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