Bone and Muscle by Chiazor Nwokoma https://padlet.com/w1648398/ozb8u2vvcil2 Histology of muscle in space. en-us 2018-02-23 11:24:38 UTC 2023-01-24 20:53:23 UTC hello@padlet.com 1. Differing histology of skeletalmuscle and of bone. w1648398 https://padlet.com/w1648398/ozb8u2vvcil2/wish/234638145 - Components of bone tissue 
(osteoprogenitor cells, osteoblasts, osteocytes, and osteoclasts, collagen fibres, extracellular natrix) - tortora 

]]> 2018-02-23 11:26:52 UTC https://padlet.com/w1648398/ozb8u2vvcil2/wish/234638145 2. What interaction is there between bone and muscle, and what are someexamples of one affecting the other? w1648398 https://padlet.com/w1648398/ozb8u2vvcil2/wish/234638262
source 1 notes.
- "Muscle/bone relationships include two factors: local control of muscle to bone and systemic humoral interactions between muscle and bone."
- " In skeletal tissues, muscle and bone interact mechanically and functionally" 
- slow and slow twitch fibres. ]]> 2018-02-23 11:27:25 UTC https://padlet.com/w1648398/ozb8u2vvcil2/wish/234638262 3. Microgravity is an example of extreme disuse. What histological changeswould you expect to see? Can you find evidence for this? Whatcountermeasures might be trialled, and how would these (physiologically)work? w1648398 https://padlet.com/w1648398/ozb8u2vvcil2/wish/234638331 2018-02-23 11:27:44 UTC https://padlet.com/w1648398/ozb8u2vvcil2/wish/234638331 4. What are some terrestrial diseases / disorders that are similar to what you’ve described so far? Are the cellular changes similar? w1648398 https://padlet.com/w1648398/ozb8u2vvcil2/wish/234638386 - astronaut osteoporosis : cant be a disease of ages because athletes do come across tis after 4 months in space.
-  sarcopenia
(look for atrophies]]> 2018-02-23 11:28:01 UTC https://padlet.com/w1648398/ozb8u2vvcil2/wish/234638386 Skeletal Muscle w1634591 https://padlet.com/w1648398/ozb8u2vvcil2/wish/234640197 https://www.thinglink.com/scene/844755702852354049]]> 2018-02-23 11:37:13 UTC https://padlet.com/w1648398/ozb8u2vvcil2/wish/234640197 w1632538 https://padlet.com/w1648398/ozb8u2vvcil2/wish/234641970 http://www.lab.anhb.uwa.edu.au/mb140/corepages/muscle/Images/skem042he.jpg
Endomysium - inner layer folded into the perimysium and separates individual muscle fibres (in one fasicle) from each other]]> 2018-02-23 11:45:41 UTC https://padlet.com/w1648398/ozb8u2vvcil2/wish/234641970 Labelled bone histology w1632538 https://padlet.com/w1648398/ozb8u2vvcil2/wish/234642550 https://www.colorado.edu/intphys/iphy3415/histology/index.html]]> 2018-02-23 11:48:31 UTC https://padlet.com/w1648398/ozb8u2vvcil2/wish/234642550 Labelled Sarcomere w1632538 https://padlet.com/w1648398/ozb8u2vvcil2/wish/234646519 https://embryology.med.unsw.edu.au/embryology/index.php/Skeletal_Muscle_Histology
also contains the proteins actin, myosin and titin (WileyPLUS, chapter 10.2)]]> 2018-02-23 12:08:00 UTC https://padlet.com/w1648398/ozb8u2vvcil2/wish/234646519 The effect of prolonged space flight on skeletal muscle, NASA w1668508 https://padlet.com/w1648398/ozb8u2vvcil2/wish/234647285 2018-02-23 12:11:46 UTC https://padlet.com/w1648398/ozb8u2vvcil2/wish/234647285 w1648398 https://padlet.com/w1648398/ozb8u2vvcil2/wish/234649952 2018-02-23 12:26:07 UTC https://padlet.com/w1648398/ozb8u2vvcil2/wish/234649952 Apocrine vs eccrine glands w1632538 https://padlet.com/w1648398/ozb8u2vvcil2/wish/249163928 https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3904096/#!po=7.44681https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3904096/#!po=7.44681]]> 2018-04-06 10:16:16 UTC https://padlet.com/w1648398/ozb8u2vvcil2/wish/249163928 w1632538 https://padlet.com/w1648398/ozb8u2vvcil2/wish/249165176 https://accessmedicine.mhmedical.com/Content.aspx?bookId=392&sectionId=41138789https://accessmedicine.mhmedical.com/Content.aspx?bookId=392&sectionId=41138789]]> 2018-04-06 10:23:47 UTC https://padlet.com/w1648398/ozb8u2vvcil2/wish/249165176 https://discovery.lifemapsc.com/library/review-of-medical-embryology/chapter-74-development-of-the-hair-and-associated-structures w1632538 https://padlet.com/w1648398/ozb8u2vvcil2/wish/249165999
  • Sweat (eccrine or merocrine) glands develop as a solid epidermal bud which grows down into the underlying dermis
  • AS THE BUD ELONGATES, its end coils to form the primordium of the glands secretory portion, while the epithelial attachment to the epidermis forms the duct primordium
  • The central cells of the primordia degenerate to form a lumen
  • The peripheral cells of the secretory portion of the gland differentiate into secretory and myoepithelial cells, the latter being specialized ectodermal smooth muscle cells which aid in expelling the glandular secretion
  • Sweat (apocrine) glands in humans, are confined to the axilla, pubic areas, and areola of the mammary glands
  • THEY DEVELOP as downgrowths of the stratum germinativum of the epidermis
  • Their ducts open into the hair follicles and not on the skin surfac They open just above the sebaceous glands
  • Their chief function seems to be the production of small amounts of secretions which, on the surface, give rise to distinctive odors that enable animals to recognize each other. Human apocrine sweat glands have no odor in their secretion but contain substances readily degraded by bacteria into odiferous breakdown products

    • ]]>     2018-04-06 10:28:11 UTC https://padlet.com/w1648398/ozb8u2vvcil2/wish/249165999     w1632538 https://padlet.com/w1648398/ozb8u2vvcil2/wish/249170238 2018-04-06 10:52:31 UTC https://padlet.com/w1648398/ozb8u2vvcil2/wish/249170238 w1648398 https://padlet.com/w1648398/ozb8u2vvcil2/wish/249174582 https://www.sciencedirect.com/science/article/pii/S0079633602800055]]> 2018-04-06 11:17:44 UTC https://padlet.com/w1648398/ozb8u2vvcil2/wish/249174582 w1632538 https://padlet.com/w1648398/ozb8u2vvcil2/wish/249177323 Devi, V.S. (2017). Inderbir Singh's Human Embryology, 11th edition. Jaypee Brothers Medical Publishers, 122.
    Goldsmith, L.A. Et al. (2012). Fitzpatrick's Dermatology in General Medicine, 8th edition. United States: McGraw-Hill.
    Li, C. and Fuchs, E. (2014). Sweat Gland Progenitors in Development, Homeostasis, and Wound Repair. Cold Spring Harbor Perspectives in Medicine, 4 (2). Available from doi:10.1101/cshperspect.a015222 [Accessed 06 April 2018].
    Pansky, B. (1982). Review of Medical Embryology. Ohio: Macmillan USA.
    Saga, K. (2002). Structure and function of human sweat glands studied with histochemistry and cytochemistry. Progress in Histochemistry and Cytochemistry, 37 (4), 323 - 386. Avalable from doi:10.1016/S0079-6336(02)80005-5 [Accessed 06 April 2018].
    Tortora, G.J. and Derrickson, B.H. (2016). Principles of Anatomy and Physiology, 15th ed. Wiley. 
    ]]>     2018-04-06 11:31:11 UTC https://padlet.com/w1648398/ozb8u2vvcil2/wish/249177323