https://padlet.com/1056029/osfwgyq5tfh9pscm en-us 2022-05-03 21:15:25 UTC 2022-05-06 20:23:21 UTC hello@padlet.com 1056029 https://padlet.com/1056029/osfwgyq5tfh9pscm/wish/2168975758 2022-05-03 21:18:01 UTC https://padlet.com/1056029/osfwgyq5tfh9pscm/wish/2168975758 1056029 https://padlet.com/1056029/osfwgyq5tfh9pscm/wish/2168976291 2022-05-03 21:18:41 UTC https://padlet.com/1056029/osfwgyq5tfh9pscm/wish/2168976291 1056029 https://padlet.com/1056029/osfwgyq5tfh9pscm/wish/2168976790 2022-05-03 21:19:17 UTC https://padlet.com/1056029/osfwgyq5tfh9pscm/wish/2168976790 1056029 https://padlet.com/1056029/osfwgyq5tfh9pscm/wish/2168977296 2022-05-03 21:19:53 UTC https://padlet.com/1056029/osfwgyq5tfh9pscm/wish/2168977296 1056029 https://padlet.com/1056029/osfwgyq5tfh9pscm/wish/2168978106 2022-05-03 21:20:47 UTC https://padlet.com/1056029/osfwgyq5tfh9pscm/wish/2168978106 1056029 https://padlet.com/1056029/osfwgyq5tfh9pscm/wish/2168978403 2022-05-03 21:21:08 UTC https://padlet.com/1056029/osfwgyq5tfh9pscm/wish/2168978403 1056029 https://padlet.com/1056029/osfwgyq5tfh9pscm/wish/2169356948 2022-05-04 04:02:13 UTC https://padlet.com/1056029/osfwgyq5tfh9pscm/wish/2169356948 1056029 https://padlet.com/1056029/osfwgyq5tfh9pscm/wish/2169357095 2022-05-04 04:02:28 UTC https://padlet.com/1056029/osfwgyq5tfh9pscm/wish/2169357095 1056029 https://padlet.com/1056029/osfwgyq5tfh9pscm/wish/2169357248 2022-05-04 04:02:43 UTC https://padlet.com/1056029/osfwgyq5tfh9pscm/wish/2169357248 1056029 https://padlet.com/1056029/osfwgyq5tfh9pscm/wish/2169357537 2022-05-04 04:03:11 UTC https://padlet.com/1056029/osfwgyq5tfh9pscm/wish/2169357537 1056029 https://padlet.com/1056029/osfwgyq5tfh9pscm/wish/2169364679 Sickle cell disease, or sickle cell anemia, is an inherited blood disorder that modifies the shape of the red blood cells in your body. The cells would change into a sickle shape, which can affect your blood flow and the amount of oxygen being carried out through your body.^2,5]]> 2022-05-04 04:14:24 UTC https://padlet.com/1056029/osfwgyq5tfh9pscm/wish/2169364679 1056029 https://padlet.com/1056029/osfwgyq5tfh9pscm/wish/2169385042 1. Centers for Disease Control and Prevention | https://www.cdc.gov/ncbddd/sicklecell/data.html#:~:text=SCD%20affects%20approximately%20100%2C000%20Americans,sickle%20cell%20trait%20(SCT).
2. Genetic and Rare Diseases Information Center | https://rarediseases.info.nih.gov/diseases/8614/sickle-cell-anemia
3. Heart Research Funding | https://healthresearchfunding.org/famous-people-sickle-cell-anemia-disease/
4. Howard University Hospital | http://huhealthcare.com/healthcare/hospital/specialty-services/sickle-cell-disease-center/disease-information/breif-history#:~:text=The%20disorder%20we%20call%20%E2%80%9CSickle,but%20in%20the%20United%20States.
5. Mayo Clinic | https://www.mayoclinic.org/diseases-conditions/sickle-cell-anemia/symptoms-causes/syc-20355876#:~:text=In%20sickle%20cell%20anemia%2C%20some,all%20parts%20of%20the%20body.
6. National Human Genome Research Institute | https://www.genome.gov/Genetic-Disorders/Sickle-Cell-Disease#:~:text=Sickle%20cell%20disease%20is%20caused,and%20glide%20through%20blood%20vessels.
7. Sickle Cell Disease Foundation | https://www.scdfc.org/]]> 2022-05-04 04:44:39 UTC https://padlet.com/1056029/osfwgyq5tfh9pscm/wish/2169385042 1056029 https://padlet.com/1056029/osfwgyq5tfh9pscm/wish/2169397391 Sickle cell disease is caused by chromosome 11, which contains the HBB gene that has a mutation for that disease. The HBB gene is a part of hemoglobin, the protein in red blood cells that carries oxygen from your lungs to the rest of your body. Hemoglobin-A is in normal red blood cells that allow an easy blood flow. However, hemoglobin-S mutates the blood cells into a sickle shape causing easier blood blockages.^2,6]]> 2022-05-04 05:00:53 UTC https://padlet.com/1056029/osfwgyq5tfh9pscm/wish/2169397391 1056029 https://padlet.com/1056029/osfwgyq5tfh9pscm/wish/2169429463 Due to blood blockage from the sickle cells, it can affect the organs in your body because they are not receiving the oxygen or blood they need to continue working. This can cause extreme pain, severe infections, and damage to your nerves and organs (kidneys, liver, etc.)^2,5]]> 2022-05-04 05:44:52 UTC https://padlet.com/1056029/osfwgyq5tfh9pscm/wish/2169429463 1056029 https://padlet.com/1056029/osfwgyq5tfh9pscm/wish/2170582084 Millions of people are affected by sickle cell disease throughout the world. It's quite common for people whose ancestry comes from sub-Saharan Africa, South America, Saudi Arabia, Turkey, and other Mediterranean countries, as well. Black and African-American offspring are more likely affected with 1 in 13 babies being born with the sickle cell trait.^1,6]]> 2022-05-04 20:53:17 UTC https://padlet.com/1056029/osfwgyq5tfh9pscm/wish/2170582084 1056029 https://padlet.com/1056029/osfwgyq5tfh9pscm/wish/2170887054 Sickle cell anemia is an inherited autosomal recessive disease that is passed down when both parents carry one copy of the mutated gene. The parents usually do not have the disease itself, but they do carry the gene that could possibly cause their offspring to have it. These parents are called carriers. If both parents have the mutated gene, it is a 1 in 4 chance of having a child with sickle cell disease.^2,6]]> 2022-05-05 03:51:19 UTC https://padlet.com/1056029/osfwgyq5tfh9pscm/wish/2170887054 1056029 https://padlet.com/1056029/osfwgyq5tfh9pscm/wish/2170896751 For this disease, a blood test can be taken to determine any form of sickle cell inheritance. It would check whether hemoglobin-S mutations were in your blood or not. This routine is implemented in newborn screening procedures in the United States.^2,5,6]]> 2022-05-05 04:07:41 UTC https://padlet.com/1056029/osfwgyq5tfh9pscm/wish/2170896751 1056029 https://padlet.com/1056029/osfwgyq5tfh9pscm/wish/2170912605 Most treatments for this disease are to relieve any pain, complications, and severe symptoms. Medications, like L-glutamine oral powder, voxelotor, other pain-relieving substances, and blood transfusions can be used to treat the effects of sickle cell anemia. Children and teenagers might also have the option of stem cell transplants that can possibly cure the disease.^2,5,6]]> 2022-05-05 04:36:28 UTC https://padlet.com/1056029/osfwgyq5tfh9pscm/wish/2170912605 1056029 https://padlet.com/1056029/osfwgyq5tfh9pscm/wish/2170927792 Sickle cell disease has been an established disease in Africa for at least five thousand years. However, not until 1910 was it officially discovered in the United States. Chemists Dr. Linus Pauling and Dr. Harvery Itano discovered that hemoglobin in an individual with SCD was chemically shaped differently than regular hemoglobin.⁴]]> 2022-05-05 05:05:41 UTC https://padlet.com/1056029/osfwgyq5tfh9pscm/wish/2170927792 1056029 https://padlet.com/1056029/osfwgyq5tfh9pscm/wish/2170942942 There are many different types of support you can get when dealing with sickle cell anemia. Lots of patients receive psychosocial support, which helps with their mental, emotional, and social health. Others are more inclined to talk to a genetic counselor for professional advice. There are, also, various foundations, like the Sickle Cell Disease Foundation of California, that help educate and provide services and programs that empower people with sickle cell disease.⁷]]> 2022-05-05 05:32:46 UTC https://padlet.com/1056029/osfwgyq5tfh9pscm/wish/2170942942 1056029 https://padlet.com/1056029/osfwgyq5tfh9pscm/wish/2170955246 As time goes by, there is more and more awareness being spread about this disease. Singer Tionne "T-Boz" Watkins and actor Larenz Tate are both individuals with sickle cell anemia. They have used their platforms to spread awareness of the disease and support organizations that do that, as well. There is, also, World Sickle Cell Day that brings awareness to the disease on an international level.³]]> 2022-05-05 05:53:39 UTC https://padlet.com/1056029/osfwgyq5tfh9pscm/wish/2170955246