https://padlet.com/georgiarenn19/ogy498q8jhoq Health and Human Development en-us 2019-04-10 13:28:55 UTC 2019-04-12 05:29:50 UTC hello@padlet.com georgiarenn19 https://padlet.com/georgiarenn19/ogy498q8jhoq/wish/350345015 Health and Human Development 
Joav Merrick - Series Editor 

]]> 2019-04-10 13:31:36 UTC https://padlet.com/georgiarenn19/ogy498q8jhoq/wish/350345015 georgiarenn19 https://padlet.com/georgiarenn19/ogy498q8jhoq/wish/350346124 In the western world cannabis was only used as a fiber source until the mid- 1800s. However, once introduced for its pharmacological benefits, its quickly played an important role in medicine as early as the 20th century (31). 
Quote Book]]> 2019-04-10 13:33:47 UTC https://padlet.com/georgiarenn19/ogy498q8jhoq/wish/350346124 georgiarenn19 https://padlet.com/georgiarenn19/ogy498q8jhoq/wish/350347699 Early in its introduction, cannabis was included in numerous over the counter and prescription drugs and referenced in many medical texts (32).
Quote Book]]> 2019-04-10 13:36:56 UTC https://padlet.com/georgiarenn19/ogy498q8jhoq/wish/350347699 georgiarenn19 https://padlet.com/georgiarenn19/ogy498q8jhoq/wish/350348837 However, in the mid-20th century, the use of cannabis underwent to a major cultural shift going from a medication to the status of being an illicit drug and its therapeutic applications were soon deterred by as a result of changes in the law (33). 
Quote Book]]> 2019-04-10 13:39:24 UTC https://padlet.com/georgiarenn19/ogy498q8jhoq/wish/350348837 georgiarenn19 https://padlet.com/georgiarenn19/ogy498q8jhoq/wish/350351018 As a medication, however, cannabis had many strengths and potential applications, however, one of the main reasons of its initial decline was the growing use of alternative analgesics (33). ]]> 2019-04-10 13:43:38 UTC https://padlet.com/georgiarenn19/ogy498q8jhoq/wish/350351018 georgiarenn19 https://padlet.com/georgiarenn19/ogy498q8jhoq/wish/350372204 Initially the decline in cannabis medical uses were practical: it was insoluble in water making it incompatible with hypodermic needles, and its delayed onset of at least an hour when consumed, posed a challenge for new quick acting analgesics (33).]]> 2019-04-10 14:23:36 UTC https://padlet.com/georgiarenn19/ogy498q8jhoq/wish/350372204 georgiarenn19 https://padlet.com/georgiarenn19/ogy498q8jhoq/wish/350374285 Ultimately, physicians found it difficulty to work around these issues and analgesics such as aspirin, heroin and chloral hydrate, which were easily administered, fast acting and constant, began to phase out cannabis (33).]]> 2019-04-10 14:27:18 UTC https://padlet.com/georgiarenn19/ogy498q8jhoq/wish/350374285 georgiarenn19 https://padlet.com/georgiarenn19/ogy498q8jhoq/wish/350398399 In light of these developments and based off growing evidence of the medical application of cannabis, the perception of cannabis is once again changing.]]> 2019-04-10 15:14:38 UTC https://padlet.com/georgiarenn19/ogy498q8jhoq/wish/350398399 georgiarenn19 https://padlet.com/georgiarenn19/ogy498q8jhoq/wish/350398578 We are seeing a general trend towards cannabis once again becoming a part of western Medicine as evidenced by its legal status for medicinal use in Canada (37).]]> 2019-04-10 15:14:56 UTC https://padlet.com/georgiarenn19/ogy498q8jhoq/wish/350398578 georgiarenn19 https://padlet.com/georgiarenn19/ogy498q8jhoq/wish/350398689 Use of cannabis as a medicine should be re-evaluated using modern approach of science and medicine to determine its true value as a therapeutic agent.]]> 2019-04-10 15:15:10 UTC https://padlet.com/georgiarenn19/ogy498q8jhoq/wish/350398689 georgiarenn19 https://padlet.com/georgiarenn19/ogy498q8jhoq/wish/350402225 In the United States, 47,000 people died of drug overdose in 2014 and 61% of deaths assosiated with drug overdose involved prscription opioids of which oxycodone and hyderocodone being the most frequently percribed (45-47).]]> 2019-04-10 15:21:50 UTC https://padlet.com/georgiarenn19/ogy498q8jhoq/wish/350402225 georgiarenn19 https://padlet.com/georgiarenn19/ogy498q8jhoq/wish/350402367 Overall, cannabis offers a low risk profile and effective alternative in pain management]]> 2019-04-10 15:22:03 UTC https://padlet.com/georgiarenn19/ogy498q8jhoq/wish/350402367 georgiarenn19 https://padlet.com/georgiarenn19/ogy498q8jhoq/wish/350404848 2019-04-10 15:26:22 UTC https://padlet.com/georgiarenn19/ogy498q8jhoq/wish/350404848 georgiarenn19 https://padlet.com/georgiarenn19/ogy498q8jhoq/wish/350405082 The medical cultural apprehension surrounding utility of cannabis in clinical practice is understandable.]]> 2019-04-10 15:26:47 UTC https://padlet.com/georgiarenn19/ogy498q8jhoq/wish/350405082 georgiarenn19 https://padlet.com/georgiarenn19/ogy498q8jhoq/wish/351044740 In comparison, the parallels to the stories of plant experts becoming pharmaceuticals, and the benefits and acceptance today. ]]> 2019-04-12 05:02:38 UTC https://padlet.com/georgiarenn19/ogy498q8jhoq/wish/351044740 georgiarenn19 https://padlet.com/georgiarenn19/ogy498q8jhoq/wish/351045027 Many of these stories have evolved without controversy, while others have been fraught with social and cultural challenges as well as significant health risks.]]> 2019-04-12 05:05:23 UTC https://padlet.com/georgiarenn19/ogy498q8jhoq/wish/351045027 georgiarenn19 https://padlet.com/georgiarenn19/ogy498q8jhoq/wish/351045490 However, in the case of cannabis and in comparison to the story of opioids, history is showing us a reasonable and feasible path forward.]]> 2019-04-12 05:09:02 UTC https://padlet.com/georgiarenn19/ogy498q8jhoq/wish/351045490 georgiarenn19 https://padlet.com/georgiarenn19/ogy498q8jhoq/wish/351046043 The difference, however, in the cannabis story is that the final clinical utility resides in the plant itself and not just a single compound. ]]> 2019-04-12 05:13:39 UTC https://padlet.com/georgiarenn19/ogy498q8jhoq/wish/351046043 georgiarenn19 https://padlet.com/georgiarenn19/ogy498q8jhoq/wish/351046388 Cannabis will continue to be a viable and beneficial clinical tool, but with ongoing education and research, there is great potential for further discoveries to the application of cannabis in medicine.]]> 2019-04-12 05:15:50 UTC https://padlet.com/georgiarenn19/ogy498q8jhoq/wish/351046388