Aminoglycosides by Ashley Thomas https://padlet.com/ashleythomas887/o2bw2pi2ymp8l6e0 en-us 2022-11-22 14:57:21 UTC 2025-12-09 17:01:18 UTC hello@padlet.com BLACK BOX WARNING ashleythomas887 https://padlet.com/ashleythomas887/o2bw2pi2ymp8l6e0/wish/2394712266
Neurotoxicity may manifest as ototoxicity - produce a loss of hearing or balance, which may become permanent

Neuromuscular Blockage and Respiratory Paralysis - the drug may cause severe neuromuscular weakness that last for several days

Nephrotoxicity - Signs of reduced kidney function include oliguria, proteinuria, and elevated BUN and creatinine level]]> 2022-11-22 21:16:54 UTC https://padlet.com/ashleythomas887/o2bw2pi2ymp8l6e0/wish/2394712266 Side effects/ Adverse effects ashleythomas887 https://padlet.com/ashleythomas887/o2bw2pi2ymp8l6e0/wish/2394713032
  • Rash 
  • Nausea 
  • Vomiting
  • Diarrhea 
  • Urticaria
  • Anaphylaxis
  • Fatigue
  • Irreversible Ototoxicity
  • Nephrotoxicity
  • Superinfection


    • ]]>     2022-11-22 21:18:06 UTC https://padlet.com/ashleythomas887/o2bw2pi2ymp8l6e0/wish/2394713032     ashleythomas887 https://padlet.com/ashleythomas887/o2bw2pi2ymp8l6e0/wish/2394713362 Therapeutic Class: Antibacterial 
    Pharmacologic Class: protein synthesis inhibitor

    Suffix: Mycin and Micin
    • Tobramycin
    • Neomycin
    • Amikacin
    • Plazomicin
    • Paromomycin
    • Streptomycin
    • Gentamycin - prototype drug 
    ]]>     2022-11-22 21:18:45 UTC https://padlet.com/ashleythomas887/o2bw2pi2ymp8l6e0/wish/2394713362     Drug - drug interactions ashleythomas887 https://padlet.com/ashleythomas887/o2bw2pi2ymp8l6e0/wish/2394714002 Increased risk of ototoxicity with concurrent use of any of the following medications:
    amphotericin B, furosemide, aspirin, bumetanide, ethacrynic acid, cisplatin, paromomycin

    Increased risk of nephrotoxicity with concurrent use of any of the following medications:
    amphotericin B, capreomycin, cisplatin, polymyxin B, vancomycin

    NO food 

    NO herbal interactions

    ]]>     2022-11-22 21:19:58 UTC https://padlet.com/ashleythomas887/o2bw2pi2ymp8l6e0/wish/2394714002     MOA & Use ashleythomas887 https://padlet.com/ashleythomas887/o2bw2pi2ymp8l6e0/wish/2398221095 MOA: Acts by stopping the protein synthesis of the bacteria 

    Used to treat serious urinary, respiratory, nervous, or GI infections when less toxic antibiotics are contraindicated.  

     The common treatments:
    • Neomycin: Topical infections (skin, eyes, and ears) 
    • Paromomycin: Parasitic infection
    • Streptomycin: Tuberculosis
    • Plazomomycin: Complicated urinary tract infections (UTI) with no alternative treatment options
    ]]>     2022-11-25 19:22:14 UTC https://padlet.com/ashleythomas887/o2bw2pi2ymp8l6e0/wish/2398221095     Nursing Implications ashleythomas887 https://padlet.com/ashleythomas887/o2bw2pi2ymp8l6e0/wish/2398243998 Monitor the culture and sensitivity results before administering the medications

    If administrating penicillins or cephalosporins concurrently, administer at separate sites, at least 1 hour apart

    Adequate hydration for the patient (1500- 2000mL/day)

    Monitor patient for signs and symptoms of:
    • An allergic reaction
    • Ototoxicity
    • Neurotoxicity
    • Neuromuscular blockade

    IM administration is deep into a large muscle

    Pregnancy category C

    NO specific treatment for over dose
    ]]>     2022-11-25 20:16:40 UTC https://padlet.com/ashleythomas887/o2bw2pi2ymp8l6e0/wish/2398243998     Patient Education ashleythomas887 https://padlet.com/ashleythomas887/o2bw2pi2ymp8l6e0/wish/2398249450 Take the medication as directed for the full course of therapy

    Adequate hydration (1500-2000 mL/daily)

    Report signs of hypersensitivity, tinnitus, vertigo, hearing loss, rash, dizziness, difficulty urinating to healthcare provider immediately 

    Notify the healthcare provider if pregnant or suspected. This medication is a pregnancy class C and can cause irreversible deafness in babies

    DO NOT double dose, if dose is missed]]>     2022-11-25 20:30:27 UTC https://padlet.com/ashleythomas887/o2bw2pi2ymp8l6e0/wish/2398249450