IN MICE by James Bartlett

anhnlt — 2024-02-21 18:13:30 UTC

Animal Research that Respects Animal Rights: Extending Requirements for Research with Humans to Animals

by Angela K. Martin

https://philarchive.org/archive/MARART-26

Reused Cooking Oil Ups Risk Of Metastases In Breast Cancer Patients

2024-02-21 21:19:20 UTC

Totally misleading title and mice are not mentioned until the methods

2024-02-23 15:26:49 UTC

The article is about a research study on mice investigating how body sensations can influence emotions in the brain. The study artificially increased heartbeats in mice to a level they would experience in stressful situations. With the increased heartbeat, the mice displayed behaviour associated with anxiety and showed activity in the posterior insula, which has a lot of interoceptive circuitry connections. The article suggests the body may be able to influence emotions in the brain. The article is very clear it was based on mice and even includes pictures of mice.

Personally, I'm not comfortable with animal research, but taking a different viewpoint it is probably quite difficult to get ethical approval to conduct a similar experiment on humans.

Importance of accounting for gender differences in research on how stress affects brain cells

2024-02-26 13:21:19 UTC

https://scitechdaily.com/is-stress-gender-blind-new-research-says-no-and-the-implications-are-huge/

This study looked into the effects of stress on different brain cell types, in both male and female mice.

The fact that the study is based on mice is emphasised in the summary, start of the article, end of the article, and in the citation.

The middle of the article (which is a large bulk) summarises the study's findings. It is generally written as brain cell research, and differing stress responses by brain cells in males and females. There is little-no reference to animal/that the research was done on mice in this section.

BBC News - "How Brain Cells Die in Alzheimer's"

2024-02-26 17:33:28 UTC

The article does mention mice, but not until the very end of the article

Tickling rats to learn about which brain regions involved in play

2024-02-27 00:16:21 UTC

Playful behaviour has been observed in many species. Researchers found both tickling and playing lit up the PAG region (the midbrain region called periaqueductal gray) in rodents. The article states play and tickling involve some of the same brain circuitry. The article suggests since playful behaviour is exhibited in both animals and humans, it may be an evolutionary adaptation. The article also talks about the importance of play.

Environmental enrichment promotes adaptive responding during tests of behavioral regulation in male heterogeneous stock rats

2024-02-27 04:14:57 UTC

https://pubmed.ncbi.nlm.nih.gov/38378969/

Is clear from the start that rats are involved in the study, and is mentioned already in the abstract.

A neural circuit for male sexual behavior and reward

2024-02-27 04:17:47 UTC

https://www.cell.com/cell/fulltext/S0092-8674(23)00798-5?_returnURL=https%3A%2F%2Flinkinghub.elsevier.com%2Fretrieve%2Fpii%2FS0092867423007985%3Fshowall%3Dtrue

Title is ambiguous and has no mention of mice in the summary (in place of an abstract) which could lead to some amusement.

Wildfire Smoke Altered Brain Structures Related to Memory in Mice

2024-02-27 09:44:12 UTC

Exposure to smoke led to neurodegenerative changes for mice in the hippocampus (subcortical structure which is particularly crucial in memory and learning). The study authors postulate that this has implications for future rates of dementia and Parkinson's disease in humans, in a world more prone to wildfires due to anthropogenic climate change.

2024-02-27 15:06:44 UTC

Interesting as this talks about types of neurons for navigation and creating AI algorithms.

Loneliness hurts not just men’s mental health — it may hurt their bones, too: study

2024-02-28 01:03:34 UTC

Mice are mentioned in the article, but not until towards the end

2024-02-28 11:36:44 UTC

Pigs instead of mice. The article briefly mentions in the middle that the study was done on pigs and creates the impression it was done on humans, including the attached photo

Optimistic: One of many articles accessed on Science Daily that DID mention the use of animals in the original experiments :D

2024-02-28 17:51:14 UTC

https://www.sciencedaily.com/releases/2024/02/240220144401.htm

Gut microbes may play role in social anxiety disorder

2024-02-29 12:16:46 UTC

It is made clear that the study involved mice.

Are we inching closer to a treatment for Alzheimer's?

2024-02-29 14:40:21 UTC

The article discusses the various stumbling blocks and recent developments in the search for a treatment for Alzheimer's including a recent study considering the role of "cold shock" proteins in helping protect and repair the brain. There is one small reference to that research showing promise "in mice at least".

Although a small win is that the research paper includes a photograph of mice alongside the abstract which makes it more obvious :/

2024-03-03 19:59:47 UTC

Article highlights the role mice play in developing AI to decode pain and behaviour in animals, with human application anticipated.

2024-03-03 22:04:35 UTC

Snake venom toxins can be neutralized by a new synthetic antibody

2024-03-04 20:46:52 UTC

This article immediately and clearly mentions the use of testing on animals, specifically mice. Scientists injected their test animals with this new synthetic antibody after exposing them to two different snake toxins, and found that they were able to recover. While there currently is no singular antibody to cure every kind of toxin exposure, scientists are hopeful that this can lead to the development of a "universal" antibody one day.

Genetic switch that can control anxiety

2024-03-07 13:57:07 UTC

Article is open about a study by Aberdeen University using mice to investigate a section of DNA which affects anxiety. It explains that genes turn off and on which affects health and the study's hope to be able to understand more about the effect of being able to turn genes off and on.

The published research regarding this study indicates the focus on the effect of the gene on alcohol consumption and more specifically linked to men. The research itself may be of valuable interest in the quest to discover more about the functions of DNA but the article ignores a vast amount of information from the study cited below.

McEwan, A.R., Davidson, C., Hay, E. et al. CRISPR disruption and UK Biobank analysis of a highly conserved polymorphic enhancer suggests a role in male anxiety and ethanol intake. Mol Psychiatry 26, 2263–2276 (2021). https://doi.org/10.1038/s41380-020-0707-7

"Social anxiety might be transmissible through gut microbiota, study finds"

2024-03-13 22:42:53 UTC

https://www.psypost.org/social-anxiety-might-be-transmissible-through-gut-microbiota-study-finds/

#toughweekforavegan

'Universal' brain wave pattern discovered across primate species — including humans

2024-03-14 19:24:28 UTC

"the distinct activity patterns may reflect how the brain consciously switches focus from one piece of information to the next."

Addiction and Community

2024-03-17 03:54:41 UTC

This articles talks about the fact that when rats are in a community where they are free to roam, socialise etc, they are much less likely to choose the option of opioid-laced water compared to rats that are isolated and given the option of opioids or normal water. It helps researchers understand that community might be the key to battling drug addiction.