https://padlet.com/MsLeCour/n49diasq3abh5vsi Based on POL Textbook p 138-143. https://drive.google.com/file/d/1xZK5iaVnUHQ-3-FZ8pwAnzC_FAYbVzxJ/view?usp=sharing en-us 2021-04-01 16:51:31 UTC 2021-05-17 12:55:56 UTC hello@padlet.com https://padlet.net/icons/png/1f42e.png toquend004 https://padlet.com/MsLeCour/n49diasq3abh5vsi/wish/1396338584 (1) Describe cyclin-dependent kinases: the kinases involved in cell cycle regulation 
(2) Describe what happens when CDKs bind to cyclins: When CBKs binds to cyclins the shape of CBKs exposing there active sites. This is an example of an allosteric regulation.
(3) Describe the four cell cycle checkpoints. The four cell cycle checkpoints are G1 checkpoint, S checkpoint, G2 checkpoint and M checkpoint. The G1 checkpoint is triggered by DNA damage, the S checkpoint is triggered by incomplete replication or DNA damage, the G2 checkpoint is triggered by DNA damage, and the M checkpoint is triggered by a chromosome that fails to attach to the spindle
(4) What are the three overall functions that meiosis has evolved to serve: To reduce the chromosome number from diploid to haploid, to ensure that each of the haploid products has a complete set of chromosomes, and to generate genetic diversity among the products (gametes)
(5) Use pages 142-143 to describe the events of meiosis 1 and meiosis 2: The evets of meiosis 1 includes the replication of each chromosome resulting in two sister chromatids in each chromosome. At the end of meiosis 1 two nuclei form, each with half of the original chromosomes. Meiosis 2 includes the separation of the sister chromatids (not proceeded by DNA replication) resulting in 4 cells that aren't genetical identical but each containing the haploid number of chromosomes.]]> 2021-04-08 15:17:00 UTC https://padlet.com/MsLeCour/n49diasq3abh5vsi/wish/1396338584 https://padlet.com/MsLeCour/n49diasq3abh5vsi/wish/1401972403 (1) The kinase involved in cell cycle regulation are called cyclin-dependent kinase. They catalyze the phosphorylation of target proteins that regulate the cell cycle.
(2) This binding changes the shape of a CDK such that it’s active site is exposed, and is an example of allosteric regulation.
(3) The G1 checkpoint is triggered by DNA damage. S checkpoint is triggered by incomplete replication or DNA damage. G2 checkpoint is triggered by DNA damage. M checkpoint is triggered by a chromosome that fails to attach to the spindle.
(4) To reduce the chromosome number from diploid to haploid. To ensure that each of the haploid products has a complete set of chromosomes. To generate diversity among the products (gametes).
(5) 1-the chromatin begins to condense following interphase. 2-synapsis aligns homologs, and chromosomes condense further.
3-The chromosomes continue to coil and shorten. The chiasmata reflects crossing over, the exchange of genetic material between no sister chromatids in a homologous pair. In prometaphase the nuclear envelope breaks down.  4-The homologous pairs line up on the equatorial (metaphase) plate. 5-The homologous chromosomes move to opposite poles of the cell. 6-The chromosomes gather into nuclei and the original cell divides. 7-The chromosomes condense again, following a brief interphase in which DNA does not replicate. 8-The centromere of the paired chromatids lineup across the equatorial plates of each cell. 9-The chromatids finally separate, becoming chromosomes in their own right. Because of crossing over and independent assortment, each new cell will have a different genetic makeup. 10-The chromosomes gather into nuclei, and the cells divide. 11-Each of the four cells has a nucleus with a haploid haploid number of chromosomes.]]> 2021-04-10 03:30:19 UTC https://padlet.com/MsLeCour/n49diasq3abh5vsi/wish/1401972403 kleonce6152 https://padlet.com/MsLeCour/n49diasq3abh5vsi/wish/1416787690 1) Cyclin-dependent kinases: Controls the cell cycle, Common in cell signaling, and catalyze the phosphorylation of target proteins that regulate the cell cycle. 
2) When CDKs bind to cyclins it changes the CDKs shape so that its active site is then exposed which is an example of allosteric regulation. 
3) The four cell checkpoints are G1, S, G2, and M. The G1 checkpoint is triggered by DNA damage, S checkpoint is triggered by incomplete replication or DNA damage, G2 checkpoint is triggered by DNA damage, and M checkpoint os triggered by a chromosome that fails to attach to the spindle. 
4) The three functions that meiosis has evolve to serve are to reduce the chromosome number of diploid to haploid, to ensure that each of the haploid products has a complete set of chromosomes, and to generate genetic diversity among the products (gametes).
5) 1: the chromatin begins to condense following interphase. 2: synapsis aligns homologs, and chromosomes condense further.
3: The chromosomes continue to coil and shorten. The chiasmata reflects crossing over, the exchange of genetic material between nonsister chromatids in a homologous pair. In prometaphase the nuclear envelope breaks down.  4: The homologous pairs line up on the equatorial (metaphase) plate. 5: The homologous chromosomes move to opposite poles of the cell. 6: The chromosomes gather into nuclei and the original cell divides. 7: The chromosomes condense again, following a brief interphase in which DNA does not replicate. 8: The centromere of the paired chromatids line up across the equatorial plates of each cell. 9: The chromatids finally separate, becoming chromosomes in their own right and are pulled to the opposite sides of the poles. Because of crossing over and independent assortment, each new cell will have a different genetic makeup. 10: The chromosomes gather into nuclei, and the cells divide. 11: Each of the four cells has a nucleus with a haploid number of chromosomes.]]> 2021-04-14 14:52:01 UTC https://padlet.com/MsLeCour/n49diasq3abh5vsi/wish/1416787690 mgraham536 https://padlet.com/MsLeCour/n49diasq3abh5vsi/wish/1432487010 (1) The cyclin- dependent kinases is a cell cycle regulation. In this process they catalyze th phosphorylation of target proteins that regulate the cell cycle. 
(2) What happens when CDK bind to cyclins is they're activated. This binding will start to change the shape of a CDK.
(3) The four cell cycle checkpoints is G1, S, G2, and M:
G1- Triggered by DNA damage 
S- Triggered by incomplete replication or DNA damage
G2- Triggered by DNA damage 
M- Triggered by a chromosome that fails to attach to the spindle 
(4) The three overall functions that meiosis has evolved to serve is 1. To reduce the chromosomes number from diploid to haploid, 2. To ensure that each of the haploid products has a complete set of chromosomes, and 3. To generate genetic diversity among the products ( gametes)
(5) The events of meiosis 1 &2 is:
Meiosis 1-
Stage 1: The chromatin begins to condense following interphase
Stage 2: Synapsis aligns homologous, and chromosomes condense further
Stage 3: The chromosomes continue to coil and shorten. The chiasmata reflect crossing over, the exchange of genetic material between non sister chromatids in a homologs pair. In prometaphase the nuclear envelope breaks down 
Stage 4: The homologous pairs line up n the equatorial ( metaphase) plate
Stage 5: The homologous chromosomes ( each with two chromatids) move to opposite poles of the cell
Stage 6: The chromosomes gather into nuclei, and the original cell divides
Then Meiosis 2
Stage 7: The chromosomes condense again, following a brief interphase ( interkinesis) in which DNA does not replicate
Stage 8: The centromeres of the paired chromatids line up across the equatorial plates of each cell
Stage 9:The chromatids finally separate, becoming chromosomes in their own rights, and are pulled to opposite poles. Because of crossing over and independent assortment, each new cell will have a different genetic makeup
Stage 10: The chromosomes gather into nuclei, and the cell divide
Stage 11; Each of the four cells has a nucleus with haploid number of chromosomes ]]> 2021-04-19 11:12:02 UTC https://padlet.com/MsLeCour/n49diasq3abh5vsi/wish/1432487010 https://padlet.com/MsLeCour/n49diasq3abh5vsi/wish/1440179462 1) Cell cyclin dependent kinases are the cells that are responsible for cell cycle regulation. They catalyze the phosphorylation of target protiens that regulate the cell cycle.
2) When CDKS binds to cyclins  the shape of it starts to change and the cyclins are activated.
3) The first cell cycle checkpoint is G1 which is triggerd by damage. The next is S which is triggerd by incomplete replication or dna damage, next is G2 which is triggerrd by dna damage and lastly M which is triggerd by a chromosome that fails to attach to the spindle.
4)The three overall functions tht meiosis had evolved to serve are to reduce the chromosome number of diploid to haploid,to ensure that each haploid products have a complete set of chromosomes and to generate genetic diversity among the products.
5)The evets of meiosis 1 includes the replication of each chromosome resulting in two sister chromatids in each chromosome. At the end of meiosis 1 two nuclei form, each with half of the original chromosomes. Meiosis 2 includes the separation of the sister chromatids (not proceeded by DNA replication) resulting in 4 cells that aren't genetical identical but each containing the haploid number of chromosomes]]> 2021-04-20 22:23:46 UTC https://padlet.com/MsLeCour/n49diasq3abh5vsi/wish/1440179462 https://padlet.com/MsLeCour/n49diasq3abh5vsi/wish/1476826107 1. Cyclin-dependent kinases is a cell cycle regulation. They catalyze the phosphorylation of target proteins that regulate the cell cycle.
2. When CDKS bind to cyclins when the shape of it starts to change and then the cyclins are activated. 
3. The four cell cycle checkpoints is G1, then  S, then G2 and lastly it is M, 
4. The three overall functions that meiosis has evolved to serve are to reduce the chromosome number of diploid to haploid. 
5.  Meiosis 1 is that the replication of each chromosome resulting in two sister chromatids in each chromosome. Meiosis 2 is the separation of the sister chromatids (not proceeded by DNA replication) resulting in 4 cells that aren't genetical identical but each containing the haploid number of chromosomes.]]> 2021-04-30 03:55:16 UTC https://padlet.com/MsLeCour/n49diasq3abh5vsi/wish/1476826107 https://padlet.com/MsLeCour/n49diasq3abh5vsi/wish/1530997385 1. Cyclin are the dependent kinases is a cell cycle regulation. They catalyze the phosphorylation of target proteins that regulate the cell cycle
2. When CDKS bind to cyclins when the shape of it starts to change and then the cyclins are activated. 
3) The first cell cycle checkpoint is G1 which is triggerd by damage. The next is S which is triggerd by incomplete replication or dna damage, next is G2 which is triggerrd by dna damage and lastly M which is triggerd by a chromosome that fails to attach to the spindle.
4)The three overall functions tht meiosis had evolved to serve are to reduce the chromosome number of diploid to haploid,to ensure that each haploid products have a complete set of chromosomes and to generate genetic diversity among the products.
5.  Meiosis 1 is that the replication of each chromosome resulting in two sister chromatids in each chromosome. Meiosis 2 is the separation of the sister chromatids (not proceeded by DNA replication) resulting in 4 cells that aren't genetical identical but each containing the haploid number of chromosomes.

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