BIOL-K101 Project Poliovirus by

1. CDC Page: Poliovirus

kpeduhan — 2023-12-06 21:06:48 UTC

Depicted above are children holding up their marked pinkie fingers after getting vaccinated for the poliovirus.

2. What is Polio?

kpeduhan — 2023-12-06 21:13:46 UTC

Poliovirus, the causative agent of polio (also known as poliomyelitis), is a serotype of the species Enterovirus C, in the family of Picornaviridae.

Poliovirus is composed of an RNA genome and a protein capsid. The genome is a single-stranded positive-sense RNA. Because of its short genome and its simple configuration, poliovirus is often seen as the simplest significant virus.

Poliovirus has become a useful model system for understanding the biology of RNA viruses.

4. Three Symptoms and Conditions

kpeduhan — 2023-12-06 21:18:48 UTC

About 1 out of 4 people (or 25 out of 100) with poliovirus infection will have flu-like symptoms that last 2-5 days, then go away on their own.

A smaller proportion of people with poliovirus infection will develop other, more serious symptoms, affecting the brain and spinal cord:

Meningitis
Paralysis

Paralysis is the most severe symptom associated with poliovirus because it can lead to permanent disability and death. Between 2 and 10 out of 100 people who have paralysis from poliovirus infection die, because the virus affects the muscles that help them breathe.

3. Causative Agent

kpeduhan — 2023-12-06 21:27:03 UTC

5. Diagnosis

kpeduhan — 2023-12-06 21:27:20 UTC

Healthcare providers who suspect a patient has polio should hospitalize the patient right away, do a physical exam, take detailed medical history( vaccination history and history of any recent travel), collect samples (stool, throat swab, blood, urine, and spinal fluid), and get a MRI to look at the spinal cord. Poliovirus is most likely to be detected in stool specimens.

6. Treatment

kpeduhan — 2023-12-06 21:27:36 UTC

"There is no cure for paralytic polio and no specific treatment. Physical or occupational therapy can help with arm or leg weakness caused by polio and might improve long-term outcomes, especially if implemented early in the course of illness. Healthcare providers should consider consulting neurology and infectious disease experts to discuss possible treatments and recommend certain interventions on a case-by-case basis." (CDC)

7. Emerging Threats/Successes

kpeduhan — 2023-12-06 21:28:02 UTC

Abstract graphic showing a proposal for a new vaccine for poliovirus

8. Infographic or other Health-Related Image

kpeduhan — 2023-12-06 21:28:30 UTC

https://images.app.goo.gl/9ipnYWg4yi4Etixx7

9. Featured Scientist

kpeduhan — 2023-12-06 21:31:11 UTC

https://jp.linkedin.com/in/ming-te-yeh-943418b0

10. Learn More

kpeduhan — 2023-12-06 21:34:09 UTC

source: UC Davis Health

11. Breathing by Mark O'Brien

kpeduhan — 2023-12-06 21:35:00 UTC

Grasping for straws is easier;
You can see the straws.
“This most excellent canopy, the air, look you,”
Presses down upon me
At fifteen pounds per square inch,
A dense, heavy, blue-glowing ocean,
Supporting the weight of condors
That swim its churning currents.
All I get is a thin stream of it,
A finger’s width of the rope that ties me to life
As I labor like a stevedore to keep the connection.
Water wouldn’t be so circumspect;
Water would crash in like a drunken sailor,
But air is prissy and genteel,
Teasing me with its nearness and pervading immensity.
The vast, circumambient atmosphere
Allows me but ninety cubic centimeters
Of its billions of gallons and miles of sky.
I inhale it anyway,
Knowing that it will hurt
In the weary ends of my crumpled paper bag lungs.