https://padlet.com/shsanders02/n1q6n9holchw Creutzfeldt-Jakob Disease en-us 2018-03-02 00:16:37 UTC 2026-01-04 12:58:27 UTC hello@padlet.com shsanders02 https://padlet.com/shsanders02/n1q6n9holchw/wish/237240278 Creutzfeldt-Jakob Disease is a human prion disease. It is a neurodegenerative disorder with characteristic clinical and diagnostic features. This disease is rapidly progressive and always fatal. Infection with this disease leads to death usually within one year of onset of illness. CJD is believed to be caused by an abnormal isoform of a cellular glycoprotein known as the prion protein. There is no specific therapy that has been shown to stop the progression of prion disease, including CJD. The most common form of CJD is believed to occur sporadically, caused by the spontaneous transformation of normal prion proteins into abnormal prions. This sporadic disease occurs worldwide, at a rate of roughly 1.5 cases per 1 million people per year. Symptoms of CJD include rapid mental deterioration, usually within a few months. Other signs and symptoms typically include: personality changes, anxiety, depression, memory loss, impaired thinking, blurred vision or blindness, insomnia, difficulty speaking, difficulty swallowing, sudden jerking movements.  

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