https://padlet.com/amamay030/mlg5clf7r1rg Made while exhausted en-us 2019-03-08 15:02:55 UTC 2026-02-20 20:53:59 UTC hello@padlet.com amamay030 https://padlet.com/amamay030/mlg5clf7r1rg/wish/339330101 An action potential is sent to a neuromuscular junction. This causes the calcium ion channels to open and calcium ions will enter the neuron. This stimulates the release of the neurotransmitter acetylcholine, which leave the axon terminal. The voltage gated sodium channel open pumping Na+ in and K+ out. The cell interior in now depolarized. The depolarization moves down the sarcolemma. The sodium concentrations cause the opening of voltage gated K+ pumps. K+ diffuse across the sarcolemma which is called repolarization. ]]> 2019-03-08 15:06:57 UTC https://padlet.com/amamay030/mlg5clf7r1rg/wish/339330101 amamay030 https://padlet.com/amamay030/mlg5clf7r1rg/wish/339331296 Step 1:  The AP will move down the sarcolemma and down the T tubules which is a deep protrusion in the muscle cell.

 

]]> 2019-03-08 15:09:06 UTC https://padlet.com/amamay030/mlg5clf7r1rg/wish/339331296 amamay030 https://padlet.com/amamay030/mlg5clf7r1rg/wish/339331622 Step 2: The transmission of the AP in the T tubules cause the adjacent sarcoplasmic reticulum to release calcium into the cytosol.]]> 2019-03-08 15:09:37 UTC https://padlet.com/amamay030/mlg5clf7r1rg/wish/339331622 amamay030 https://padlet.com/amamay030/mlg5clf7r1rg/wish/339332149 Step 3 and 4: Calcium combines with troponin which removes the blocking protein of tropomyosin. This exposes the myosin binding site. The myosin binds to actin forming a cross bridge. Contractions will now start.

]]> 2019-03-08 15:10:30 UTC https://padlet.com/amamay030/mlg5clf7r1rg/wish/339332149 amamay030 https://padlet.com/amamay030/mlg5clf7r1rg/wish/339332600 step 1: The energized myosin head attaches to an actin microfilament, forming the cross bridge.]]> 2019-03-08 15:11:20 UTC https://padlet.com/amamay030/mlg5clf7r1rg/wish/339332600 amamay030 https://padlet.com/amamay030/mlg5clf7r1rg/wish/339370274 Step 4: As ATP is hydrolyzed to ADP and Pi, the myosin head returns to its prestroke high-energy.]]> 2019-03-08 16:27:21 UTC https://padlet.com/amamay030/mlg5clf7r1rg/wish/339370274 amamay030 https://padlet.com/amamay030/mlg5clf7r1rg/wish/339370422 Step 3: After ATP attaches to myosin, the link between the myosin and actin weakens. The myosin head then detaches.]]> 2019-03-08 16:27:39 UTC https://padlet.com/amamay030/mlg5clf7r1rg/wish/339370422 amamay030 https://padlet.com/amamay030/mlg5clf7r1rg/wish/339370613 step 2: ADP and Pi are released and the myosin head pivots, changing to its low energy bent state. This pulls the actin filament toward the M line.]]> 2019-03-08 16:28:03 UTC https://padlet.com/amamay030/mlg5clf7r1rg/wish/339370613