Hormones! by Heather Murray https://padlet.com/hglenville/lmhsw7tnoz0djke8 en-us 2021-12-31 22:41:24 UTC 2022-01-04 20:01:00 UTC hello@padlet.com Leptin https://padlet.com/hglenville/lmhsw7tnoz0djke8/wish/1975020570 Leptin - a hormone produced and secreted by the adipose tissues
Blood leptin concentration is controlled by food intake and the amount of adipose tissues in your body.
What do they do?
  • Leptin receptors can be found in the hypothalamus of the brain
  • the hypothalamus is the appetite control centre of the brain
  • once received by receptors they cause appetite inhibition
  •  if fat mass decreases, the level of plasma leptin falls so that appetite is stimulated until fat mass recovers
  • if fat mass increases, leptin levels increase and appetite is suppressed until weight loss occurs
  • leptin regulates energy intake and fat stores
  • makes sure weight is maintained in a narrow range
Leptin Resistance
People who are obese have very high levels of leptin in their blood. This implies that the receptor cells are no longer responsive to leptin, so appetite is not inhibited. This leads to obesity.
Mutated Gene
The gene that codes for leptin is called OB, and when it is not mutated it correctly codes for leptin. If it becomes mutated, it will not code correctly for leptin. Without functional leptin, no leptin signal is received by the hypothalamus, so appetite is not inhibited, which causes obesity.  
]]> 2022-01-04 19:47:27 UTC https://padlet.com/hglenville/lmhsw7tnoz0djke8/wish/1975020570 Thyroxin https://padlet.com/hglenville/lmhsw7tnoz0djke8/wish/1975032788 Function:
- regulates metabolism and body temperature

Where it is produced:
- thyroid gland

Disorders
- Goitre: Since iodine is required to produce thyroxine, iodine deficiency can cause a condition called Goitre. This causes an enlargement of the thyroid gland. Treatment involves supplementation with iodine tablets or increasing the amount of iodine in the diet with foods like fish, dairy products, and iodized salt.



]]> 2022-01-04 19:54:35 UTC https://padlet.com/hglenville/lmhsw7tnoz0djke8/wish/1975032788 Melatonin https://padlet.com/hglenville/lmhsw7tnoz0djke8/wish/1975043294 Melatonin is a hormone which promotes effects of sleep in humans. However, it is not the primary regulator of sleep. 

Peptide hormone released from the pineal gland
Secretion increase in the evening and drops at dawn

Acts on cells with a melatonin receptor (M1 and M2)

Multiple tissue types are affected by melatonin

Higher concentrations cause drowsiness and promote sleep

Higher concentrations drop core body temperature

Higher concentrations reduce kidney production of urine

Disorders - sleep insomnia in teens
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