Toxicology Final Project by Hannah Ewings https://padlet.com/676482/lkmf3r1tsl2j Natural Toxins and Controlled Substances en-us 2018-11-13 18:48:31 UTC 2018-11-23 20:15:06 UTC hello@padlet.com Scientific Name 676482 https://padlet.com/676482/lkmf3r1tsl2j/wish/303967102 Lysergic Acid Diethylamide ]]> 2018-11-13 19:03:26 UTC https://padlet.com/676482/lkmf3r1tsl2j/wish/303967102 Common Name 676482 https://padlet.com/676482/lkmf3r1tsl2j/wish/303967193 Acid, LSD]]> 2018-11-13 19:03:37 UTC https://padlet.com/676482/lkmf3r1tsl2j/wish/303967193 Scientific Name 676482 https://padlet.com/676482/lkmf3r1tsl2j/wish/303967954 Aconitum Napellus]]> 2018-11-13 19:04:44 UTC https://padlet.com/676482/lkmf3r1tsl2j/wish/303967954 Common Name 676482 https://padlet.com/676482/lkmf3r1tsl2j/wish/303968067 monkshood, wolf's bane, leopard's bane, mousebane, women's bane, devil's helmet, queen of poisons, or blue rocket,]]> 2018-11-13 19:04:53 UTC https://padlet.com/676482/lkmf3r1tsl2j/wish/303968067 Categorized 676482 https://padlet.com/676482/lkmf3r1tsl2j/wish/303968146 Family: Ranunculaceae
Genus: Aconitum
Species: A. napellus]]> 2018-11-13 19:04:59 UTC https://padlet.com/676482/lkmf3r1tsl2j/wish/303968146 Categorized 676482 https://padlet.com/676482/lkmf3r1tsl2j/wish/303968213 Hallucinogen]]> 2018-11-13 19:05:06 UTC https://padlet.com/676482/lkmf3r1tsl2j/wish/303968213 Effects 676482 https://padlet.com/676482/lkmf3r1tsl2j/wish/303968284 Central Nervous System
  • body temperature regulation
    • hypothermia
  • Agonist for Serotonin receptors
Cardiovascular
  • temporary moderate increased heart rate
]]> 2018-11-13 19:05:13 UTC https://padlet.com/676482/lkmf3r1tsl2j/wish/303968284 Effects 676482 https://padlet.com/676482/lkmf3r1tsl2j/wish/303968422 Neurological
  • Activate sodium channels with excessive depolarization  
  • convulsions, paralysis, pain
Cardiovascular
  • slows and stops heart
  •  monoesters block sodium channel and cause irregular rhythms
]]> 2018-11-13 19:05:24 UTC https://padlet.com/676482/lkmf3r1tsl2j/wish/303968422 Poisonous Toxicity Level 676482 https://padlet.com/676482/lkmf3r1tsl2j/wish/303968885
  • 2 mg of aconitine
    • death within 4 hours
  • 5 ml of aconite tincture
  • 1 g of the raw aconite plant
    • ]]>     2018-11-13 19:06:02 UTC https://padlet.com/676482/lkmf3r1tsl2j/wish/303968885     Poisonous Toxicity Level 676482 https://padlet.com/676482/lkmf3r1tsl2j/wish/303968997 >200μg or not pure Lysergic Acid Diethylamide ]]> 2018-11-13 19:06:11 UTC https://padlet.com/676482/lkmf3r1tsl2j/wish/303968997 Symptoms of Low Toxicity Level 676482 https://padlet.com/676482/lkmf3r1tsl2j/wish/303969200
  • skin irritation
  • upset stomach
  • face and mouth numbing
  • cold and clammy skin
  • dizziness
  • chest pain
  • defective color vision
    • ]]>     2018-11-13 19:06:27 UTC https://padlet.com/676482/lkmf3r1tsl2j/wish/303969200     Symptoms of Low Toxicity Level 676482 https://padlet.com/676482/lkmf3r1tsl2j/wish/303969518 50-200μg or 75 and 150 micrograms 
    • hallucinations
    • low self-awareness
    • anxiety
    • paranoid thinking
    • discomfort
    • confusion
    • increase in blood pressure 
    • increased heart rate
    • joy
    • happiness
    • possible catatonic state
    • increase time if schizophrenic traits
    • dryness of mouth
    • profuse sweating
    • nausea
    • numbness
    • weakness
    • tremors
    • dilated pupils
    • paranoia of not returning to normal
    • poor judgement
    • feelings of invincibility
    ]]>     2018-11-13 19:06:50 UTC https://padlet.com/676482/lkmf3r1tsl2j/wish/303969518     Symptoms of Poisonous Level 676482 https://padlet.com/676482/lkmf3r1tsl2j/wish/303969598 Rare overdoses
    • hypothermia
    • increased blood pressure
    • increased heart rate
    • seizures
    • stroke
    • kidney failure
    • paranoia lead accidents
    • gastric bleeding
    • coma
    Usually trauma related injuries
    ]]>     2018-11-13 19:06:58 UTC https://padlet.com/676482/lkmf3r1tsl2j/wish/303969598     Symptoms of Poisonous Level 676482 https://padlet.com/676482/lkmf3r1tsl2j/wish/303969869
  • heart failure
  • paralysis
  • convulsions
  • low blood pressure
  • dangerously low heart rate/pulse
  • irregular heart rate
  • gastrointestinal: nausea, vomiting, diarrhea
  • mouth, face, or tongue burning, tingling, or numb
  • inflammation
  • burning in the abdomen
  • difficulty breathing
  • cold and clammy skin
  • confusion
  • mania
    • ]]>     2018-11-13 19:07:20 UTC https://padlet.com/676482/lkmf3r1tsl2j/wish/303969869     Time it Stays in Body 676482 https://padlet.com/676482/lkmf3r1tsl2j/wish/303969995 Aconite can be spit out if not fully ingested otherwise will kill the animal or person rapidly.
    Aconite can be processed for medicinal purposes without scientific reports of how long the results last.]]>     2018-11-13 19:07:29 UTC https://padlet.com/676482/lkmf3r1tsl2j/wish/303969995     Time it Stays in Body 676482 https://padlet.com/676482/lkmf3r1tsl2j/wish/303970218 8-18 hours]]> 2018-11-13 19:07:47 UTC https://padlet.com/676482/lkmf3r1tsl2j/wish/303970218 Treatment for Overdose 676482 https://padlet.com/676482/lkmf3r1tsl2j/wish/303970422 No known antidotes.
    Wear gloves when working around it and don't ingest it.
    Overdose is death.]]>     2018-11-13 19:08:05 UTC https://padlet.com/676482/lkmf3r1tsl2j/wish/303970422     Treatment for Overdose 676482 https://padlet.com/676482/lkmf3r1tsl2j/wish/303970591
  • sedated with benzodiazepines (lorazepam or diazepam)
  • rapid fluid hydration
    • ]]>     2018-11-13 19:08:19 UTC https://padlet.com/676482/lkmf3r1tsl2j/wish/303970591     Forensic Test 676482 https://padlet.com/676482/lkmf3r1tsl2j/wish/303970732
  • Fluorescence- blue florescence
  • Ehrlich Reagent- color testing
  • TLC- hromatography
    • ]]>     2018-11-13 19:08:29 UTC https://padlet.com/676482/lkmf3r1tsl2j/wish/303970732     Forensic Test 676482 https://padlet.com/676482/lkmf3r1tsl2j/wish/303970795 Autopsies- Alkaloid
    • concentration of Aconite in blood and urine
    • highest levels in liver and kidneys
    • lower levels in heart and cerebrum
    Pathological and histopathological tests
    Scene
    • residue
    ]]>     2018-11-13 19:08:33 UTC https://padlet.com/676482/lkmf3r1tsl2j/wish/303970795     Health Benefits 676482 https://padlet.com/676482/lkmf3r1tsl2j/wish/303970958
  • reduce joint and muscle pain
    • in Chinese and Ayurveda medicine
    • ]]>     2018-11-13 19:08:43 UTC https://padlet.com/676482/lkmf3r1tsl2j/wish/303970958     Health Benefits 676482 https://padlet.com/676482/lkmf3r1tsl2j/wish/303971079
  • joy
  • happiness
  • decrease depression
  • stimulate circulation
    • ]]>     2018-11-13 19:08:54 UTC https://padlet.com/676482/lkmf3r1tsl2j/wish/303971079     Legality 676482 https://padlet.com/676482/lkmf3r1tsl2j/wish/303971173 Schedule I drug
    Sale, possession, and use is illegal in the United States because there are no significant medicinal uses.]]>     2018-11-13 19:09:01 UTC https://padlet.com/676482/lkmf3r1tsl2j/wish/303971173     Legality 676482 https://padlet.com/676482/lkmf3r1tsl2j/wish/303971209 Wolfsbane is grown in the wild but illegal as a method of poison.]]> 2018-11-13 19:09:04 UTC https://padlet.com/676482/lkmf3r1tsl2j/wish/303971209 Facts 676482 https://padlet.com/676482/lkmf3r1tsl2j/wish/303971306
  • Wolfsbane was used to poison carnivores by putting it in raw meat for the animals to eat.
  • Shakespeare wrote about wolfsbane acting as a poison on the blade in Hamlet.
    • ]]>     2018-11-13 19:09:11 UTC https://padlet.com/676482/lkmf3r1tsl2j/wish/303971306     Facts 676482 https://padlet.com/676482/lkmf3r1tsl2j/wish/303971352
  • First developed by Albert Hoffmann in 1938 and marketed for medicinal use under the name of Delysid.
  • The CIA and US Army started experiments for mind control with LSD in the 1950s.
    • ]]>     2018-11-13 19:09:15 UTC https://padlet.com/676482/lkmf3r1tsl2j/wish/303971352     676482 https://padlet.com/676482/lkmf3r1tsl2j/wish/304952687 "Wolfsbane: fictitous plant contains very real dangers | - The Evergreen ...." 31 Jan. 2017, https://sites.evergreen.edu/plantchemeco/wolfsbane-fictious-plant-contains-very-real-dangers/. Accessed 19 Nov. 2018.]]> 2018-11-15 18:23:31 UTC https://padlet.com/676482/lkmf3r1tsl2j/wish/304952687 676482 https://padlet.com/676482/lkmf3r1tsl2j/wish/304964996  "Monkshood (Wolfsbane) poisoning - Monica Wilde." 28 Jun. 2015, https://monicawilde.com/monkshood-wolfsbane-poisoning/. Accessed 19 Nov. 2018.]]> 2018-11-15 18:45:10 UTC https://padlet.com/676482/lkmf3r1tsl2j/wish/304964996 676482 https://padlet.com/676482/lkmf3r1tsl2j/wish/304990253  "Aconitum napellus (Monkshood): A Purple Poison - Poison Control." https://www.poison.org/articles/why-is-monkshood-considered-a-poison--174. Accessed 19 Nov. 2018.

    ]]>     2018-11-15 19:28:26 UTC https://padlet.com/676482/lkmf3r1tsl2j/wish/304990253     676482 https://padlet.com/676482/lkmf3r1tsl2j/wish/304994030 "Monkshood - AACC.org." https://www.aacc.org/community/divisions/tdm-and-toxicology/toxin-library/monkshood. Accessed 19 Nov. 2018.]]> 2018-11-15 19:34:28 UTC https://padlet.com/676482/lkmf3r1tsl2j/wish/304994030 676482 https://padlet.com/676482/lkmf3r1tsl2j/wish/306075594  "Is LSD toxic? - NCBI." 2 Feb. 2018, https://www.ncbi.nlm.nih.gov/pubmed/29408722. Accessed 19 Nov. 2018.]]> 2018-11-19 19:03:47 UTC https://padlet.com/676482/lkmf3r1tsl2j/wish/306075594 676482 https://padlet.com/676482/lkmf3r1tsl2j/wish/306083236 "LSD: Everything You Need to Know | TripSafe.org." https://tripsafe.org/lsd/. Accessed 19 Nov. 2018.]]> 2018-11-19 19:19:37 UTC https://padlet.com/676482/lkmf3r1tsl2j/wish/306083236 676482 https://padlet.com/676482/lkmf3r1tsl2j/wish/306083477 "The Effects of Acid - DrugAbuse.com." https://drugabuse.com/library/effects-acid-lsd/. Accessed 19 Nov. 2018.]]> 2018-11-19 19:20:05 UTC https://padlet.com/676482/lkmf3r1tsl2j/wish/306083477 676482 https://padlet.com/676482/lkmf3r1tsl2j/wish/306083941 "LSD - National Library of Medicine HSDB Database - Toxnet - NIH." https://toxnet.nlm.nih.gov/cgi-bin/sis/search/a?dbs+hsdb:@term+@DOCNO+3920. Accessed 19 Nov. 2018.]]> 2018-11-19 19:21:00 UTC https://padlet.com/676482/lkmf3r1tsl2j/wish/306083941 676482 https://padlet.com/676482/lkmf3r1tsl2j/wish/306084102 "Analysis of a controlled substance: LSD - Marshall University." http://www.marshall.edu/forensics/files/Nunney-Analysis-of-a-controlled-substance-LSD-Final-Version.pdf. Accessed 19 Nov. 2018.]]> 2018-11-19 19:21:20 UTC https://padlet.com/676482/lkmf3r1tsl2j/wish/306084102