https://padlet.com/iylafeist1/lixg1jpun66m The disease that affects 100,000 Americans en-us 2018-03-18 16:00:19 UTC 2023-07-01 19:23:30 UTC hello@padlet.com https://padlet-assets.s3.amazonaws.com/icons/Diskette.png iylafeist1 https://padlet.com/iylafeist1/lixg1jpun66m/wish/243206323 2018-03-18 16:03:12 UTC https://padlet.com/iylafeist1/lixg1jpun66m/wish/243206323 iylafeist1 https://padlet.com/iylafeist1/lixg1jpun66m/wish/243206472 2018-03-18 16:04:10 UTC https://padlet.com/iylafeist1/lixg1jpun66m/wish/243206472 iylafeist1 https://padlet.com/iylafeist1/lixg1jpun66m/wish/243243407 2018-03-18 19:50:54 UTC https://padlet.com/iylafeist1/lixg1jpun66m/wish/243243407 iylafeist1 https://padlet.com/iylafeist1/lixg1jpun66m/wish/243244890 Many people with SCD live in chronic pain and often get anemia due to low blood cell count. Some other symptoms include:

• Shortness of breath and/or dizziness
• Headache
• Coldness in the hands and feet
• Pale skin due to anemia
• Jaundice, or yellow eyes and skin
• Chest pain
• Leg ulcers that do not heal

]]> 2018-03-18 20:00:36 UTC https://padlet.com/iylafeist1/lixg1jpun66m/wish/243244890 iylafeist1 https://padlet.com/iylafeist1/lixg1jpun66m/wish/243245081 In the United States a simple blood test can show if you have SCD and testing is required at newborn screenings.]]> 2018-03-18 20:01:45 UTC https://padlet.com/iylafeist1/lixg1jpun66m/wish/243245081 iylafeist1 https://padlet.com/iylafeist1/lixg1jpun66m/wish/243245339 In people younger than 16 bone marrow transplants or stem cell transplants can be used and offer the only potential cure for SCD. However the risks are too high for those over 16 and donors are very hard to find, so most of the time treatment is found with medication and vaccines. Blood transfusion is another option but the risk of infection and iron buildup are not safe. In future years we may research more into gene therapy and its effectiveness towards SCD but it is not fully developed or available to the public for use. ]]> 2018-03-18 20:03:20 UTC https://padlet.com/iylafeist1/lixg1jpun66m/wish/243245339 iylafeist1 https://padlet.com/iylafeist1/lixg1jpun66m/wish/243246404 2018-03-18 20:10:33 UTC https://padlet.com/iylafeist1/lixg1jpun66m/wish/243246404 iylafeist1 https://padlet.com/iylafeist1/lixg1jpun66m/wish/243247384 2018-03-18 20:15:55 UTC https://padlet.com/iylafeist1/lixg1jpun66m/wish/243247384 iylafeist1 https://padlet.com/iylafeist1/lixg1jpun66m/wish/243302646 2018-03-19 02:17:51 UTC https://padlet.com/iylafeist1/lixg1jpun66m/wish/243302646 iylafeist1 https://padlet.com/iylafeist1/lixg1jpun66m/wish/243809696 The first report of Sickle-Cell Disease or SCD was by Ernest E. Irons in 1910, when he saw what he described as "elongated sickle shaped cells"in a patient. More and more cases of this were reported and it wasn't until 1933 that Lemuel Diggs made the connection between genetic traits. Further understandings have shown that the affected hemoglobin gene has a higher affect on ancestral malaria stricken areas meaning that 80% of SCD carriers are African-American. ]]> 2018-03-20 01:24:44 UTC https://padlet.com/iylafeist1/lixg1jpun66m/wish/243809696 iylafeist1 https://padlet.com/iylafeist1/lixg1jpun66m/wish/243814327 Distribution of Sickle-Cell trait]]> 2018-03-20 01:49:55 UTC https://padlet.com/iylafeist1/lixg1jpun66m/wish/243814327 iylafeist1 https://padlet.com/iylafeist1/lixg1jpun66m/wish/243814875 Distribution of malaria]]> 2018-03-20 01:52:57 UTC https://padlet.com/iylafeist1/lixg1jpun66m/wish/243814875 iylafeist1 https://padlet.com/iylafeist1/lixg1jpun66m/wish/243815113 https://www.mayoclinic.org/diseases-conditions/sickle-cell-anemia/diagnosis-treatment/drc-20355882
https://www.pixton.com/create/storyboard/mn38fbmc
https://en.wikipedia.org/wiki/Sickle-cell_disease
https://ghr.nlm.nih.gov/condition/sickle-cell-disease
https://medlineplus.gov/magazine/issues/winter11/articles/winter11pg18.html
https://www.webmd.com/a-to-z-guides/tc/sickle-cell-disease-treatment-overview#1
https://www.nhlbi.nih.gov/health-topics/sickle-cell-disease

]]> 2018-03-20 01:54:17 UTC https://padlet.com/iylafeist1/lixg1jpun66m/wish/243815113 iylafeist1 https://padlet.com/iylafeist1/lixg1jpun66m/wish/248725767 Sickle-cell disease is a common genetically inherited blood disorder. It gets the name sickle-cell because the red blood cells look like a crescent sickle shape instead of a full circle. Because of the irregular shape the red blood cell's hemoglobin, the part that carries blood throughout the body, is not smooth and flexible like normal. This causes a block of blood flow. 80,000-100,000 Americans have sickle cell disease.]]> 2018-04-05 02:31:52 UTC https://padlet.com/iylafeist1/lixg1jpun66m/wish/248725767 iylafeist1 https://padlet.com/iylafeist1/lixg1jpun66m/wish/248727451 Sickle-cell disease is inherited, meaning you are born with it and it can not be gained later in life. To get SCD both parents have do be carriers of the defective hemoglobin-beta gene in chromosome 11. You have a 1 in 4 chance of inheriting it.]]> 2018-04-05 02:42:59 UTC https://padlet.com/iylafeist1/lixg1jpun66m/wish/248727451 iylafeist1 https://padlet.com/iylafeist1/lixg1jpun66m/wish/248728627 Support groups:
http://www.ascaa.org/support-groups.php
http://www.sicklecellsociety.org/]]> 2018-04-05 02:53:08 UTC https://padlet.com/iylafeist1/lixg1jpun66m/wish/248728627