https://padlet.com/charissa4/l3n0uq9cfkgs Joseph Kim & Charissa Kim en-us 2018-03-13 23:36:31 UTC 2023-01-21 00:18:44 UTC hello@padlet.com joseph_kim3 https://padlet.com/charissa4/l3n0uq9cfkgs/wish/241665843 Family Pedigree]]> 2018-03-13 23:46:45 UTC https://padlet.com/charissa4/l3n0uq9cfkgs/wish/241665843 charissa4 https://padlet.com/charissa4/l3n0uq9cfkgs/wish/241667816 Yes, Jane has a good reason to be worried because cancer clearly runs in her family. Therefore, it is possible that either she or her children may also have colon cancer.]]> 2018-03-13 23:59:09 UTC https://padlet.com/charissa4/l3n0uq9cfkgs/wish/241667816 charissa4 https://padlet.com/charissa4/l3n0uq9cfkgs/wish/241668922 If a tumor is classified as "benign", it means that the tumor does not invade nearby tissue. It is not a cancerous tumor, and it is only an issue if it presses on blood vessels or nerves.

If a tumor is classified as "malignant", it means that the tumor is cancerous, and can spread to other parts of the body. ]]> 2018-03-14 00:06:46 UTC https://padlet.com/charissa4/l3n0uq9cfkgs/wish/241668922 charissa4 https://padlet.com/charissa4/l3n0uq9cfkgs/wish/241669295 Benign tumors are less likely to harm your body, as the outlook is very good, unless it interferes with vital structures. However, malignant tumors are harder to treat because they are cancerous and must be found before it spreads throughout your body.]]> 2018-03-14 00:08:50 UTC https://padlet.com/charissa4/l3n0uq9cfkgs/wish/241669295 charissa4 https://padlet.com/charissa4/l3n0uq9cfkgs/wish/241669535 When someone is predisposed to cancer, due to cancer running in their family, that person may have a higher risk of developing a similar type of cancer.]]> 2018-03-14 00:10:36 UTC https://padlet.com/charissa4/l3n0uq9cfkgs/wish/241669535 charissa4 https://padlet.com/charissa4/l3n0uq9cfkgs/wish/241669791 No. It only suggests that there is a higher possibility. It is not a guarantee.]]> 2018-03-14 00:12:23 UTC https://padlet.com/charissa4/l3n0uq9cfkgs/wish/241669791 charissa4 https://padlet.com/charissa4/l3n0uq9cfkgs/wish/242628321 At one point, Sam's DNA has an "A" where there should be a "T". ]]> 2018-03-15 23:34:07 UTC https://padlet.com/charissa4/l3n0uq9cfkgs/wish/242628321 charissa4 https://padlet.com/charissa4/l3n0uq9cfkgs/wish/242628812 The original amino acid will be replaced with a different amino acid.

The amino acid will signify a stop signal.

The amino acid might not be changed.]]> 2018-03-15 23:35:34 UTC https://padlet.com/charissa4/l3n0uq9cfkgs/wish/242628812 charissa4 https://padlet.com/charissa4/l3n0uq9cfkgs/wish/242630374 Sam's ORF1 is a lot shorter.]]> 2018-03-15 23:46:59 UTC https://padlet.com/charissa4/l3n0uq9cfkgs/wish/242630374 charissa4 https://padlet.com/charissa4/l3n0uq9cfkgs/wish/242630455 The original amino acid was replaced with another amino acid. In this case, it was most likely replaced by a STOP codon.]]> 2018-03-15 23:47:37 UTC https://padlet.com/charissa4/l3n0uq9cfkgs/wish/242630455 charissa4 https://padlet.com/charissa4/l3n0uq9cfkgs/wish/242630669 Instead of a mutation in the DNA, it might be caused because cancer runs in their family. 

However, cancer does not always have to run in the family for someone to get it. It is just as possible for someone to get cancer without a family history with cancer.]]> 2018-03-15 23:49:14 UTC https://padlet.com/charissa4/l3n0uq9cfkgs/wish/242630669 charissa4 https://padlet.com/charissa4/l3n0uq9cfkgs/wish/243274856 We would expect the mutation to increase the ability of the APC protein to bind to ß-catenin.]]> 2018-03-18 23:28:08 UTC https://padlet.com/charissa4/l3n0uq9cfkgs/wish/243274856 charissa4 https://padlet.com/charissa4/l3n0uq9cfkgs/wish/243275150 When the normal APC gene is damaged, there will be nothing to keep the levels of ß-catenin controlled, which will cause cell division to happen nonstop.]]> 2018-03-18 23:30:07 UTC https://padlet.com/charissa4/l3n0uq9cfkgs/wish/243275150 charissa4 https://padlet.com/charissa4/l3n0uq9cfkgs/wish/243275554 Oncogenes - when an oncogene is mutated, the cell continues to grow even though it normally wouldn't.

Tumor Suppressor genes - tumor suppressor genes protect a cell from one step on the cancer. When it is mutated, the cell can progress to cancer.

Stability genes - stability genes control the rate of mutations. Thus, if there is one mutated gene, then this gene will most likely cause all genes to be mutated more frequently.]]> 2018-03-18 23:33:33 UTC https://padlet.com/charissa4/l3n0uq9cfkgs/wish/243275554 charissa4 https://padlet.com/charissa4/l3n0uq9cfkgs/wish/243277366 The APC is most likely a tumor suppressor gene. 

The ß-catenin is most likely an oncogene. ]]> 2018-03-18 23:45:27 UTC https://padlet.com/charissa4/l3n0uq9cfkgs/wish/243277366 charissa4 https://padlet.com/charissa4/l3n0uq9cfkgs/wish/243277506 I think Ms. Meeker would recommend Jane to maintain a healthy diet by eating more fruits and vegetables over red meat and/or process meat. I think she would also highly suggest Jane to schedule a meeting with her doctor regularly.]]> 2018-03-18 23:46:16 UTC https://padlet.com/charissa4/l3n0uq9cfkgs/wish/243277506 https://padlet.com/charissa4/l3n0uq9cfkgs/wish/350045667 2019-04-09 17:21:06 UTC https://padlet.com/charissa4/l3n0uq9cfkgs/wish/350045667 https://padlet.com/charissa4/l3n0uq9cfkgs/wish/440904811 im pretty sure its actually decreased instead of increased looking at the diagram?]]> 2020-02-05 13:55:41 UTC https://padlet.com/charissa4/l3n0uq9cfkgs/wish/440904811 https://padlet.com/charissa4/l3n0uq9cfkgs/wish/2402151354 2022-11-29 15:56:46 UTC https://padlet.com/charissa4/l3n0uq9cfkgs/wish/2402151354