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      <title>Problems &amp; Solutions of DNA Replication by Mary Mcgehee</title>
      <link>https://padlet.com/mary_c_mcgehee/k2v366a5a3xvlj7w</link>
      <description>For each problem with replication, explain how the cell prepares/deals with it.</description>
      <language>en-us</language>
      <pubDate>2020-09-21 14:59:44 UTC</pubDate>
      <lastBuildDate>2025-09-19 13:18:50 UTC</lastBuildDate>
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      <item>
         <title>Zachary Goldman</title>
         <author></author>
         <link>https://padlet.com/mary_c_mcgehee/k2v366a5a3xvlj7w/wish/3593967585</link>
         <description><![CDATA[<p>Solution: DNA P III proofreads each nucleotide against the template nucleotide as soon as it is added. If a pairing is incorrect, it removes the wrong nucleotide and then resumes synthesis.</p>]]></description>
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         <pubDate>2025-09-19 13:14:06 UTC</pubDate>
         <guid>https://padlet.com/mary_c_mcgehee/k2v366a5a3xvlj7w/wish/3593967585</guid>
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      <item>
         <title>Catherine &amp; Tiffany</title>
         <author></author>
         <link>https://padlet.com/mary_c_mcgehee/k2v366a5a3xvlj7w/wish/3593968804</link>
         <description><![CDATA[<p>When this happens, mismatch repair can help solve this problem. Polymerase II removes the singular mismatched nucleotide and replaces it with the correct one. This ensures that the error does not continue replicating.</p>]]></description>
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         <pubDate>2025-09-19 13:14:18 UTC</pubDate>
         <guid>https://padlet.com/mary_c_mcgehee/k2v366a5a3xvlj7w/wish/3593968804</guid>
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         <title>The DNA uses incision repair to replace the existing and damaged nucleotide. It does this by removing the damaged segment and fills in the gap with new nucleotides.</title>
         <author></author>
         <link>https://padlet.com/mary_c_mcgehee/k2v366a5a3xvlj7w/wish/3593969006</link>
         <description><![CDATA[]]></description>
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         <pubDate>2025-09-19 13:14:25 UTC</pubDate>
         <guid>https://padlet.com/mary_c_mcgehee/k2v366a5a3xvlj7w/wish/3593969006</guid>
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         <title>Solution </title>
         <author></author>
         <link>https://padlet.com/mary_c_mcgehee/k2v366a5a3xvlj7w/wish/3593969238</link>
         <description><![CDATA[<p>Mismatch repair can be used to remove/replace incorrect nucleotides using Polymerase II </p>]]></description>
         <enclosure url="" />
         <pubDate>2025-09-19 13:14:32 UTC</pubDate>
         <guid>https://padlet.com/mary_c_mcgehee/k2v366a5a3xvlj7w/wish/3593969238</guid>
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         <title>If the damage is specifically UV radiation damage, certain nucleotides are melded together which interferes with replication. In response. the repair enzymes will use excision repair which completely cuts out the damaged DNA segment.</title>
         <author></author>
         <link>https://padlet.com/mary_c_mcgehee/k2v366a5a3xvlj7w/wish/3593969607</link>
         <description><![CDATA[]]></description>
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         <pubDate>2025-09-19 13:14:44 UTC</pubDate>
         <guid>https://padlet.com/mary_c_mcgehee/k2v366a5a3xvlj7w/wish/3593969607</guid>
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      <item>
         <title>Laila and Noah</title>
         <author></author>
         <link>https://padlet.com/mary_c_mcgehee/k2v366a5a3xvlj7w/wish/3593970483</link>
         <description><![CDATA[<p>Telomerase adds "useless" base pairs that don't code for anything onto existing strands of DNA that can be cut off so that important pieces of DNA can not be cut off and so the protein is not damaged. </p>]]></description>
         <enclosure url="" />
         <pubDate>2025-09-19 13:15:21 UTC</pubDate>
         <guid>https://padlet.com/mary_c_mcgehee/k2v366a5a3xvlj7w/wish/3593970483</guid>
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         <title></title>
         <author></author>
         <link>https://padlet.com/mary_c_mcgehee/k2v366a5a3xvlj7w/wish/3593970772</link>
         <description><![CDATA[<p>Special proteins fix the mistakes by using mismatch repair and excision repair. This means it gets rid of the incorrect section and replaces it with a correct one</p>]]></description>
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         <pubDate>2025-09-19 13:15:34 UTC</pubDate>
         <guid>https://padlet.com/mary_c_mcgehee/k2v366a5a3xvlj7w/wish/3593970772</guid>
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      <item>
         <title>Olivia and Jodi</title>
         <author></author>
         <link>https://padlet.com/mary_c_mcgehee/k2v366a5a3xvlj7w/wish/3593971075</link>
         <description><![CDATA[<p>Telomerase is a special enzyme that lengthens telomeres. RNA has a molecule as part of its structure which serves as a template for new telomeres segments. </p>]]></description>
         <enclosure url="" />
         <pubDate>2025-09-19 13:15:46 UTC</pubDate>
         <guid>https://padlet.com/mary_c_mcgehee/k2v366a5a3xvlj7w/wish/3593971075</guid>
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      <item>
         <title></title>
         <author></author>
         <link>https://padlet.com/mary_c_mcgehee/k2v366a5a3xvlj7w/wish/3593971606</link>
         <description><![CDATA[<p>Mismatch repair can solve this problem by replacing incorrect nucleotides as more are added during the replication process.</p>]]></description>
         <enclosure url="" />
         <pubDate>2025-09-19 13:16:09 UTC</pubDate>
         <guid>https://padlet.com/mary_c_mcgehee/k2v366a5a3xvlj7w/wish/3593971606</guid>
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         <title></title>
         <author></author>
         <link>https://padlet.com/mary_c_mcgehee/k2v366a5a3xvlj7w/wish/3593971859</link>
         <description><![CDATA[<p>DNA polymerase III proofreads each nucleotide as soon as it's added, and if there is any incorrect pairing, the enzymes remove the wrong nucleotide and resume synthesis.</p>]]></description>
         <enclosure url="" />
         <pubDate>2025-09-19 13:16:19 UTC</pubDate>
         <guid>https://padlet.com/mary_c_mcgehee/k2v366a5a3xvlj7w/wish/3593971859</guid>
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      <item>
         <title>2</title>
         <author></author>
         <link>https://padlet.com/mary_c_mcgehee/k2v366a5a3xvlj7w/wish/3593972020</link>
         <description><![CDATA[<p>cell can use excision repair to have nucleases cut out damaged DNA segments</p>]]></description>
         <enclosure url="" />
         <pubDate>2025-09-19 13:16:26 UTC</pubDate>
         <guid>https://padlet.com/mary_c_mcgehee/k2v366a5a3xvlj7w/wish/3593972020</guid>
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      <item>
         <title>Hannah &amp; Jack</title>
         <author></author>
         <link>https://padlet.com/mary_c_mcgehee/k2v366a5a3xvlj7w/wish/3593973521</link>
         <description><![CDATA[<p>The enzyme and telomerase solves the problem of shortening DNA by adding repetitive DNA sequences (telomeres) to the ends of the shortened chromosomes.</p>]]></description>
         <enclosure url="" />
         <pubDate>2025-09-19 13:17:28 UTC</pubDate>
         <guid>https://padlet.com/mary_c_mcgehee/k2v366a5a3xvlj7w/wish/3593973521</guid>
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      <item>
         <title>Newt and Scarlett</title>
         <author></author>
         <link>https://padlet.com/mary_c_mcgehee/k2v366a5a3xvlj7w/wish/3593973965</link>
         <description><![CDATA[<p>The Enzyme class called nucleases repair the existing DNA that was altered by environmental factors. Through use of Excision repair, the segment that has been damaged is cut out and the gap is filled by DNA polymerase. Factors that can damage DNA are UV rays and hydrogen peroxide that our body naturally produces. </p>]]></description>
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         <pubDate>2025-09-19 13:17:47 UTC</pubDate>
         <guid>https://padlet.com/mary_c_mcgehee/k2v366a5a3xvlj7w/wish/3593973965</guid>
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         <title></title>
         <author></author>
         <link>https://padlet.com/mary_c_mcgehee/k2v366a5a3xvlj7w/wish/3593975641</link>
         <description><![CDATA[<p>DNA uses telomerase to add noncoding nitrogen bases to the gap of DNA after replication.</p>]]></description>
         <enclosure url="" />
         <pubDate>2025-09-19 13:18:49 UTC</pubDate>
         <guid>https://padlet.com/mary_c_mcgehee/k2v366a5a3xvlj7w/wish/3593975641</guid>
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