For this reason, you should consult your doctor immediately if you develop a sore throat, fever, any infections, including skin infections, or begin to feel generally unwell.

If you are having long-term or intensive immunosuppressive treatment you may be at increased risk of developing lymphomas and other cancers, particularly skin cancer.

To reduce the risk of skin cancer you should minimise your exposure to strong sunlight and UV light by wearing protective clothing and using a sunscreen with a high protection factor.

Sun beds and UV light treatment such as PUVA should also be avoided. 

Females should ensure they have had a cervical smear before starting these medicines.

You should not eat grapefruit or drink grapefruit juice in the hour before taking a dose of ciclosporin as this can interfere with the medicine.

Ciclosporin can occasionally increase potassium levels in your bloodstream. For this reason you should avoid consuming excessive amounts of foods that have high potassium content, for example dried fruit, bananas, tomatoes and 'low sodium' salt, while you are taking the medicine.

You should also avoid potassium supplements.

The immune system's activity is based on its ability to distinguish characteristic proteins or protein-linked components associated with alien substances. Once this distinction has been made, certain lymphocytes are provoked to produce antibodies directed against the foreign matter, while other lymphocytes are sensitized to the invading agent and react with it directly. Thus, there are two major branches of the immune system: antibody-mediated immunity (also known as humoral immunity) and cell-mediated immunity.
1. Prevent the rejection of transplanted organs and tissues (e.g., bone marrow, heart, kidney, liver)

2. Treat autoimmune diseases or diseases that are most likely of autoimmune origin (e.g., rheumatoid arthritis, multiple sclerosis, myasthenia gravis, systemic lupus erythematosus, sarcoidosis, focal segmental glomerulosclerosis, Crohn’s disease, Behcet’s Disease, pemphigus, and ulcerative colitis)

3. Treat some other non-autoimmune inflammatory diseases (e.g., long term allergic asthma control)

4. Treat some other non-autoimmune inflammatory diseases (e.g., long term allergic asthma control)
 

Any condition that leads to end-stage renal (kidney) disease:

·         Diabetes

·         Glomerulonephritis

·         Pyelonephritis

·         Polycystic kidney disease

·         Obstructive uropathy

·         Congenital urinary tract abnormalities

·         Alport's disease

·         Hypertensive nephrosclerosis

·         Reflux nephropathy

·         Interstitial nephritis

·         IgA nephropathy

·         Goodpasture's syndrome

·         Hemolytic uremic syndrome

·         Chemical nephrotoxicity

·         Renal artery emboli

·         Sickle cell nephropathy

·         Type I diabetes with advanced nephropathy in an adult

·         Malignancy within the past two years

·         Lack of adequate social or family support

·         Significant non-compliance with medical regimen

·         Central vascular disease (aortoiliac)

·         Significant coronary artery disease Severe malnutrition/cachexia