Multiple Sclerosis by Nia Judkins https://padlet.com/niajudkins/jpw704qq3ce6 en-us 2017-10-17 12:11:06 UTC 2026-01-07 04:45:17 UTC hello@padlet.com niajudkins https://padlet.com/niajudkins/jpw704qq3ce6/wish/197738426 2017-10-17 12:30:26 UTC https://padlet.com/niajudkins/jpw704qq3ce6/wish/197738426 Incorrect Mechanism niajudkins https://padlet.com/niajudkins/jpw704qq3ce6/wish/197748916
  • Macrophages take up known  substance and present antigen to T-cells in blood.
  • Activated T-cells display adheseion molecules that allow attachment to and entry through endothelial lining of blood-brain barrier
  • Myelin Oligodendrocyte glycoprotein (MOG); highly accessible to antibodies and has been thought to be a target of immune response in MS.
  • Auto-bodies can contribute to the disease process through a variety of ways.
    • ]]>     2017-10-17 12:52:13 UTC https://padlet.com/niajudkins/jpw704qq3ce6/wish/197748916     Correct Mechanism niajudkins https://padlet.com/niajudkins/jpw704qq3ce6/wish/197748992
  • T-Cells: main component of cell-mediated immune response.
  • Help B cells augment the production of antibodies
  • T-cells help produce B cells for the production of antibodies in your immune system.
  • Perforin: pore forming protein found in most natural killer cells
    • ]]>     2017-10-17 12:52:22 UTC https://padlet.com/niajudkins/jpw704qq3ce6/wish/197748992     niajudkins https://padlet.com/niajudkins/jpw704qq3ce6/wish/197824834 2017-10-17 14:46:56 UTC https://padlet.com/niajudkins/jpw704qq3ce6/wish/197824834 About the disease shaelynraleigh https://padlet.com/niajudkins/jpw704qq3ce6/wish/197828174 - unpredictable
    -disabling disease of central nervous system
    -disrupts information between the brain and body
    most people diagnosed between 20-50
    -women are 2-3x more likely to be diagnosed than men
    -myelin is damaged which disrupts signals to brain]]>     2017-10-17 14:51:34 UTC https://padlet.com/niajudkins/jpw704qq3ce6/wish/197828174     niajudkins https://padlet.com/niajudkins/jpw704qq3ce6/wish/197831102 2017-10-17 14:55:58 UTC https://padlet.com/niajudkins/jpw704qq3ce6/wish/197831102 Cause shaelynraleigh https://padlet.com/niajudkins/jpw704qq3ce6/wish/197831118 Unknown but most scientists believe it is triggered by an environmental factor (that is hasn't yet been identified) in a person who is already genetically predisposed to respond]]> 2017-10-17 14:56:00 UTC https://padlet.com/niajudkins/jpw704qq3ce6/wish/197831118 Symptoms shaelynraleigh https://padlet.com/niajudkins/jpw704qq3ce6/wish/197833179 Numbness, tingling, mood changes, memory problems, pain, fatigue, blindness, paralysis, taking a step or solving problems becomes difficult]]> 2017-10-17 14:58:53 UTC https://padlet.com/niajudkins/jpw704qq3ce6/wish/197833179 Cell Signaling Pathway Involved shaelynraleigh https://padlet.com/niajudkins/jpw704qq3ce6/wish/197834290 -caused by axonal and neuronal damage
    -a disconnect between the body and brain
    -the spinal cord can't signal to the brain-the pathway is impaired]]>     2017-10-17 15:00:34 UTC https://padlet.com/niajudkins/jpw704qq3ce6/wish/197834290     Current Direction of Research shaelynraleigh https://padlet.com/niajudkins/jpw704qq3ce6/wish/197836735 -Difficult to diagnosis but there are modifying treatments to slow down and reduce attacks
    - Can't stop it completely but more treatments are trying to be made]]>     2017-10-17 15:04:22 UTC https://padlet.com/niajudkins/jpw704qq3ce6/wish/197836735     niajudkins https://padlet.com/niajudkins/jpw704qq3ce6/wish/197837292 2017-10-17 15:05:14 UTC https://padlet.com/niajudkins/jpw704qq3ce6/wish/197837292 Sources niajudkins https://padlet.com/niajudkins/jpw704qq3ce6/wish/197843630
  • https://ghr.nlm.nih.gov/art/large/hla.jpeg?ow
  • https://images.medicinenet.com//images/slideshow/multiple-sclerosis-s1-brain-spinal-cord-nerves.jpg
  • https://i.pinimg.com/736x/1b/31/c9/1b31c9f68c159889308913b6c0b867aa--multiple-sclerosis-awareness-illusions.jpg
  • http://pt851.wikidot.com/multiple-sclerosis-cell-bio
  • http://www.heal-wheel-india.com/blog/wp-content/uploads/2016/03/multiple-sclerosis-s11-ms-symptoms.jpg

    • ]]>     2017-10-17 15:13:39 UTC https://padlet.com/niajudkins/jpw704qq3ce6/wish/197843630