•Communication Skills Negotiate ideas and knowledge with peers and teachers

•Self Management :Organization, Select and use technology effectively and productively

•Research Skills: Understand and use technology systems

1-      Cancer therapy 

2-      Diagnostic imaging 

3-      Treats hypertension 

4-      Used in metal containing 

5-      Used as nonsteroidal anti-inflammatory drugs 

6-      Used to create multi-therapeutic medicines 

 

 

How can ligands be used in multi-therapeutic medicines?! 

First of all multi-therapeutic medicines are medicines that can cure several diseases by containing more than 1 compound that targets more than one disease in the same body at the same time. Those kinds of medicines are great because they help doctors reduce the medicine or drug damage on the patient’s body organs. Ligands help doctors create those medicines in a very simple way. When doctors need 2 compounds in a patient’s body and the 2 compounds can form a dative bond, the doctors then inject the patients with the 2 compounds at the same time with one needle, and then as the complex compound is ingested, the bond dissociates into different tissues curing several diseases at once. 

 

There is a kind of ligand called PPAR which is primarily used to cure cancer in cells. When a cell has cancer specific genes are activated which show the cancer symptoms, and those PPAR ligands along with another substance called RXR, have the ability to activate or deactivate genes in cells, hence when patient starts to have cancer, doctors may inject their bodies with the activated cancer gene with PPAR ligands and RXR which deactivate this cancer gene, and this cures cancer in the patient’s body because cells which used to divide continuously now divide in normal rates.  

 

 Since I was the first one to add my work to the paddle, I can’t really comment much on my colleagues work, but they defiantly are going to write about one of the medical uses I read about because those uses are generally limited, and this allows me to in way comment about their work. All the uses in which ligands are used for are very simple, yet greatly affect us. For example how ligands can treat cancer simply by deactivating a gene or how it can save a person’s life from poisoning by not allowing the cell to absorb metals. All these functions or uses are simple, yet greatly affect our lives 

 

 

 

Safely injecting Gadolinium ion, Ge+3 which is very toxic, into patients is an advance in diagnosis. Ge ion has the ability to strongly bind to "multidentate chelated ligands, while still having sufficient room in its coordination sphere to bind and relax water."- https://www.technology.matthey.com/article/52/1/21-22/

i'd finally like to point out the minimal info I found about ligands utilization in medicine.

 

What are ligands? 

The ligand is element usually metal attached to a central element or atom in a coordinate bonding  and act as the donor of the electron pair.

ligands have features and applications that help facilitate targeting, diagnosing, and treating diseases.

Therapeutics

Ligands are used in therapeutics : anticancers and developing a controlled or improved toxicity levels. Radioimmunotherapy,  is one example of  targeted therapeutics. 

Antibodies

Legends are also used  in advanced Medical engineering of a fully humanized antibodies which is away to avoid  the immune response for foreign antibodies

Micro Reservoir System

 

Ligands are also applied to the micro Reservoir system and liposomes which are substances made to penetrate the cell in order to deliver a specific  medication or drug, it can be used as a way to create to allow sustained release of this drug or therapy inside the body, The more basic research is needed in order to understand how this side effect the body and understand how to optimise  sustained drug release rates.