Prophase
nuclear envelope disappears, DNA coils, fiber begins to move toward center of cell


Metaphase
fibers align double chromosomes across center of cell

Anaphase
chromosomes separate at centromere, fibers separate double chromosomes into single chromosomes, single chromosomes migrate to opposite sides of cell

Telophase
nuclear envelope reappears
establishes two separate nuclei
chromosomes uncoil

3.  Division of the cytoplasm into two daughter cells is called ___cytokinesis____________________

1.  What are the two major events of interphase? Growth and preparation 

2.  What are the major parts of M-phase? Mitosis and cytokinesis

3.  Describe what happens in each of the three parts of interphase? cell growth, copies of DNA are made, cytoplasmic components are doubled

4.  What are the three processes that mitosis plays a role in?
growth, tissue repair, and asexual reproduction

5.  Mitosis ensures the transfer of ____genome from a parent cell to two genetically identical daughter cells _________________________

6.  Mitosis is usually followed by _cytokinesis______________________

7.  Based on Figure 1 at the end of the video, what percentage of the time of a full cell cycle do cells spend in interphase? 95%

1.  What are four things that are “checked” at the G1 checkpoint? cell size, nutrient, growth factor, DNA damage 

2.  What are three things that are “checked” at the G2 checkpoint? damage and replication 

3.  Name a major event that is “checked” at the M-spindle checkpoint. Fiber attaching to chromosomes properly so mitosis may occur 

4.  What is the function of cyclins?  Why do you think they were named “cyclins”? a group of related proteins associated with various phases in cell cycle. I think they were named cyclins because they promote cell cycle progression 

5.  What is the function of CDKs?  How are they activated?
Group of enzymes involved in cell cycle regulation; requires cyclin binding for activation 

6.  If the cell cycle occurs too quickly, _____apoptosis__________ can result.

7.  Why might a cell go through apoptosis?

there are disruptions to a cell cycle or a cancer 


8.  Place the following events in the cell cycle in the proper order: