Biossíntese dos Antígenos ABO, H e Le by Marcella Costa https://padlet.com/marcellacostad/j8kr2ptc3wl8akxf Atividade Aula Sistema ABO e Le en-us 2021-09-18 00:34:21 UTC 2021-09-18 01:22:53 UTC hello@padlet.com Braço Longo Cromossomo 9 marcellacostad https://padlet.com/marcellacostad/j8kr2ptc3wl8akxf/wish/1749793927 2021-09-18 00:37:39 UTC https://padlet.com/marcellacostad/j8kr2ptc3wl8akxf/wish/1749793927 Genes A, B e O marcellacostad https://padlet.com/marcellacostad/j8kr2ptc3wl8akxf/wish/1749794344 2021-09-18 00:38:07 UTC https://padlet.com/marcellacostad/j8kr2ptc3wl8akxf/wish/1749794344 Genes FUT1, FUT2 e FUT3 marcellacostad https://padlet.com/marcellacostad/j8kr2ptc3wl8akxf/wish/1749795574 2021-09-18 00:39:47 UTC https://padlet.com/marcellacostad/j8kr2ptc3wl8akxf/wish/1749795574 Braço Longo Cromossomo 19 marcellacostad https://padlet.com/marcellacostad/j8kr2ptc3wl8akxf/wish/1749795655 2021-09-18 00:39:52 UTC https://padlet.com/marcellacostad/j8kr2ptc3wl8akxf/wish/1749795655 FUT1 - α(1, 2)fucosiltransferase marcellacostad https://padlet.com/marcellacostad/j8kr2ptc3wl8akxf/wish/1749798072 Adiciona uma FUCOSE na substância precursora]]> 2021-09-18 00:42:48 UTC https://padlet.com/marcellacostad/j8kr2ptc3wl8akxf/wish/1749798072 Gene A - N-acetilgalactosamiltransferase marcellacostad https://padlet.com/marcellacostad/j8kr2ptc3wl8akxf/wish/1749799939 Adiciona o açúcar N-acetilgalactosamina ]]> 2021-09-18 00:45:03 UTC https://padlet.com/marcellacostad/j8kr2ptc3wl8akxf/wish/1749799939 Gene B - Galactosamiltransferase marcellacostad https://padlet.com/marcellacostad/j8kr2ptc3wl8akxf/wish/1749800225 Adiciona o açúcar galactose.]]> 2021-09-18 00:45:25 UTC https://padlet.com/marcellacostad/j8kr2ptc3wl8akxf/wish/1749800225 Gene O - Enzima afuncional marcellacostad https://padlet.com/marcellacostad/j8kr2ptc3wl8akxf/wish/1749800307 É incapaz de adicionar açúcar na substância precursora]]> 2021-09-18 00:45:30 UTC https://padlet.com/marcellacostad/j8kr2ptc3wl8akxf/wish/1749800307 Antígeno A marcellacostad https://padlet.com/marcellacostad/j8kr2ptc3wl8akxf/wish/1749802660 2021-09-18 00:48:19 UTC https://padlet.com/marcellacostad/j8kr2ptc3wl8akxf/wish/1749802660 Antígeno B marcellacostad https://padlet.com/marcellacostad/j8kr2ptc3wl8akxf/wish/1749802733 2021-09-18 00:48:25 UTC https://padlet.com/marcellacostad/j8kr2ptc3wl8akxf/wish/1749802733 Antígeno H marcellacostad https://padlet.com/marcellacostad/j8kr2ptc3wl8akxf/wish/1749802876 2021-09-18 00:48:36 UTC https://padlet.com/marcellacostad/j8kr2ptc3wl8akxf/wish/1749802876 Ausência do Gene H (FUT1) - [hh] marcellacostad https://padlet.com/marcellacostad/j8kr2ptc3wl8akxf/wish/1749804923 Não há atividade das enzimas que adicionam açúcares na substância precursora, inclusive a fucose (antígeno H)]]> 2021-09-18 00:50:53 UTC https://padlet.com/marcellacostad/j8kr2ptc3wl8akxf/wish/1749804923 Fenótipo Bombay marcellacostad https://padlet.com/marcellacostad/j8kr2ptc3wl8akxf/wish/1749807919 Ocorre produção de anti-H e o indivíduo se torna incompatível com doadores do tipo O.]]> 2021-09-18 00:53:24 UTC https://padlet.com/marcellacostad/j8kr2ptc3wl8akxf/wish/1749807919 [HH] ou [Hh] marcellacostad https://padlet.com/marcellacostad/j8kr2ptc3wl8akxf/wish/1749808389 2021-09-18 00:53:59 UTC https://padlet.com/marcellacostad/j8kr2ptc3wl8akxf/wish/1749808389 São genes codominantes marcellacostad https://padlet.com/marcellacostad/j8kr2ptc3wl8akxf/wish/1749813313 Os fenótipos podem ter ambas as características.
Gene A + Gene H = Antígenos A e H = Anticorpos anti-B
Gene A + Gene B = Antígenos A e B = Sem anticorpos
Gene B + Gene H = Antígeno B e H = Anticorpos anti-A
Gene H + Gene H = Antígenos H = Anticorpos anti-A e anti-B

]]> 2021-09-18 00:59:23 UTC https://padlet.com/marcellacostad/j8kr2ptc3wl8akxf/wish/1749813313 marcellacostad https://padlet.com/marcellacostad/j8kr2ptc3wl8akxf/wish/1749814962 Determina a presença ou ausência de antígenos A, B e H nos eritrócitos.]]> 2021-09-18 01:01:22 UTC https://padlet.com/marcellacostad/j8kr2ptc3wl8akxf/wish/1749814962 FUT2 - 2-α-fucosiltransferase marcellacostad https://padlet.com/marcellacostad/j8kr2ptc3wl8akxf/wish/1749816087 Adiciona uma FUCOSE no carbono 2 da substância precursora nas secreções]]> 2021-09-18 01:02:23 UTC https://padlet.com/marcellacostad/j8kr2ptc3wl8akxf/wish/1749816087 SISTEMA LEWIS marcellacostad https://padlet.com/marcellacostad/j8kr2ptc3wl8akxf/wish/1749818223 Os antígenos não são produzidos nos eritrócitos. São solúveis e presentes nos fluidos corpóreos, ou seja, são adsorvidos posteriormente na superfície eritrocitária.]]> 2021-09-18 01:04:51 UTC https://padlet.com/marcellacostad/j8kr2ptc3wl8akxf/wish/1749818223 FUT3 - 4-α-fucosiltransferase marcellacostad https://padlet.com/marcellacostad/j8kr2ptc3wl8akxf/wish/1749819723 Adiciona uma FUCOSE no carbono 4 da substância precursora nas secreções]]> 2021-09-18 01:06:39 UTC https://padlet.com/marcellacostad/j8kr2ptc3wl8akxf/wish/1749819723 marcellacostad https://padlet.com/marcellacostad/j8kr2ptc3wl8akxf/wish/1749820179 SOLÚVEIS]]> 2021-09-18 01:07:12 UTC https://padlet.com/marcellacostad/j8kr2ptc3wl8akxf/wish/1749820179 Antígeno Lea marcellacostad https://padlet.com/marcellacostad/j8kr2ptc3wl8akxf/wish/1749825025 2021-09-18 01:12:39 UTC https://padlet.com/marcellacostad/j8kr2ptc3wl8akxf/wish/1749825025 Antígeno H marcellacostad https://padlet.com/marcellacostad/j8kr2ptc3wl8akxf/wish/1749825769 2021-09-18 01:13:32 UTC https://padlet.com/marcellacostad/j8kr2ptc3wl8akxf/wish/1749825769 marcellacostad https://padlet.com/marcellacostad/j8kr2ptc3wl8akxf/wish/1749828042 Pode haver a interação dos dois genes, e ocorrer a adição de duas FUCOSES (carbonos 2 e 4)]]> 2021-09-18 01:16:05 UTC https://padlet.com/marcellacostad/j8kr2ptc3wl8akxf/wish/1749828042 Antígeno Leb marcellacostad https://padlet.com/marcellacostad/j8kr2ptc3wl8akxf/wish/1749828264 2021-09-18 01:16:18 UTC https://padlet.com/marcellacostad/j8kr2ptc3wl8akxf/wish/1749828264 Fenótipos marcellacostad https://padlet.com/marcellacostad/j8kr2ptc3wl8akxf/wish/1749833017 Le(a-b-) - Não há gene FUT3 (Gene Lewis) - Nenhuma substância do sistema é produzida
Le(a+b+) - NÃO EXISTE EM ERITRÓCITOS
Le(a-b+) - Ação do FUT3 e FUT2
Le(a+b-) - Ação apenas do FUT3]]> 2021-09-18 01:21:38 UTC https://padlet.com/marcellacostad/j8kr2ptc3wl8akxf/wish/1749833017