REVISION: PROTEINS AND ENZYMES by https://padlet.com/hidayatia17sunway/iqtajuyx21s9 Learning Outcomes • To understand the interactions that govern the folding of proteins into their functional three-dimensional shapes. • To learn about how the shape of proteins is related to their function, referring to an enzyme within a biological system and in an industrial application. en-us 2019-10-17 01:54:48 UTC 2026-03-20 21:05:45 UTC hello@padlet.com Instruction hidayatia17sunway https://padlet.com/hidayatia17sunway/iqtajuyx21s9/wish/398808412 In groups, answer the two questions below. Your answer need to be in the form of key points. Your group have 30 minutes to discuss and fill the canvas in padlet.

]]> 2019-10-17 01:54:48 UTC https://padlet.com/hidayatia17sunway/iqtajuyx21s9/wish/398808412 Question One hidayatia17sunway https://padlet.com/hidayatia17sunway/iqtajuyx21s9/wish/398808413 Oxytoxin is a hormone that causes contractions during child birth. The image of oxytoxin shown here is a ‘ball and stick’ computer model. It is a polypeptide containing nine amino acids in the sequence 

                             Cys-Tyr-lle-Gln-Asn-Cys-Pro-Leu-Gly 

The colour code of the atoms is carbon (grey), oxygen (red), nitrogen (blue), hydrogen (white) and sulfur (yellow).

a)  Refer to the model and the labels below to describe the chemical structure of this polypeptide. Your answer should include the name the chemical bond labelled A, the significance of the groups labelled B, C and D which result in the overall three-dimensional shape of oxytoxin.

b)  Suppose a mutation occurred to one of the amino acids in oxytoxin whereby isoleucine (lle) was replaced with leucine (leu). In your opinion, how would this effect the three dimensional shape of oxytoxin.

Source: https://www.sciencephoto.com/media/450344/view/oxytocin-hormone-molecule
]]> 2019-10-17 01:54:48 UTC https://padlet.com/hidayatia17sunway/iqtajuyx21s9/wish/398808413 Label A hidayatia17sunway https://padlet.com/hidayatia17sunway/iqtajuyx21s9/wish/398808414 2019-10-17 01:54:48 UTC https://padlet.com/hidayatia17sunway/iqtajuyx21s9/wish/398808414 Label C hidayatia17sunway https://padlet.com/hidayatia17sunway/iqtajuyx21s9/wish/398808416 2019-10-17 01:54:48 UTC https://padlet.com/hidayatia17sunway/iqtajuyx21s9/wish/398808416 Label D hidayatia17sunway https://padlet.com/hidayatia17sunway/iqtajuyx21s9/wish/398808417 2019-10-17 01:54:48 UTC https://padlet.com/hidayatia17sunway/iqtajuyx21s9/wish/398808417 Question 1 (b) hidayatia17sunway https://padlet.com/hidayatia17sunway/iqtajuyx21s9/wish/398808418 2019-10-17 01:54:48 UTC https://padlet.com/hidayatia17sunway/iqtajuyx21s9/wish/398808418 Question 2 hidayatia17sunway https://padlet.com/hidayatia17sunway/iqtajuyx21s9/wish/398808419 The enzyme carbonic anhydrase catalyses the decomposition of carbonic acid molecules to carbon dioxide and water in the lungs. When heated above 60°C, the enzyme becomes denatured. 

Referring to the carbonic anhydrase enzyme, describe:

]]> 2019-10-17 01:54:48 UTC https://padlet.com/hidayatia17sunway/iqtajuyx21s9/wish/398808419 i) The term denatured and how it affects the enzyme structure. hidayatia17sunway https://padlet.com/hidayatia17sunway/iqtajuyx21s9/wish/398808421 2019-10-17 01:54:48 UTC https://padlet.com/hidayatia17sunway/iqtajuyx21s9/wish/398808421 ii) How does hydrolysis differ from denaturation? hidayatia17sunway https://padlet.com/hidayatia17sunway/iqtajuyx21s9/wish/398808422 2019-10-17 01:54:48 UTC https://padlet.com/hidayatia17sunway/iqtajuyx21s9/wish/398808422 Question 2 (b) hidayatia17sunway https://padlet.com/hidayatia17sunway/iqtajuyx21s9/wish/398808423 A food company intends to produce pineapple jelly using fresh pineapple. However, the food technologist realised the enzyme in fresh pineapple can breakdown gelatine molecules instead of enabling the jelly to set. Suggest what can be done to prepare the pineapple jelly as intended. 

]]> 2019-10-17 01:54:48 UTC https://padlet.com/hidayatia17sunway/iqtajuyx21s9/wish/398808423 Label B hidayatia17sunway https://padlet.com/hidayatia17sunway/iqtajuyx21s9/wish/398808424 2019-10-17 01:54:48 UTC https://padlet.com/hidayatia17sunway/iqtajuyx21s9/wish/398808424