https://padlet.com/e_bhagwatprasad/iib61svj6mfx en-us 2018-11-19 21:59:12 UTC 2026-01-24 16:43:17 UTC hello@padlet.com https://padlet-assets.s3.amazonaws.com/icons/File.png e_bhagwatprasad https://padlet.com/e_bhagwatprasad/iib61svj6mfx/wish/306135124 This product is a drug made with CD52 monoclonal antibodies used for B-cell chronic lymphocytic leukemia. ¹]]> 2018-11-19 22:02:13 UTC https://padlet.com/e_bhagwatprasad/iib61svj6mfx/wish/306135124 e_bhagwatprasad https://padlet.com/e_bhagwatprasad/iib61svj6mfx/wish/306151385 A way to control the number of cancer cells in patients with chronic lymphocytic leukemia

About 21,000 new cases were diagnosed this year.³]]> 2018-11-19 23:20:25 UTC https://padlet.com/e_bhagwatprasad/iib61svj6mfx/wish/306151385 e_bhagwatprasad https://padlet.com/e_bhagwatprasad/iib61svj6mfx/wish/306152416 This drug works by targeting cells expressing significant levels of CD52 found on malignant lymphocytes by mediating lysis. The antibodies attach to the CD52 antigen so it can be detected by the immune system.²]]> 2018-11-19 23:27:29 UTC https://padlet.com/e_bhagwatprasad/iib61svj6mfx/wish/306152416 e_bhagwatprasad https://padlet.com/e_bhagwatprasad/iib61svj6mfx/wish/306157849 There does not appear to be ethical issues in using alemtuzumab for treating leukemia, but it has faced challenges as a treatment for multiple sclerosis regarding trials including children⁵.]]> 2018-11-20 00:06:24 UTC https://padlet.com/e_bhagwatprasad/iib61svj6mfx/wish/306157849 e_bhagwatprasad https://padlet.com/e_bhagwatprasad/iib61svj6mfx/wish/306158361

http://chemocare.com/chemotherapy/drug-info/alemtuzumab.aspx

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2767316/

https://www.cancer.org/cancer/chronic-lymphocytic-leukemia/about.html

http://www.whatisbiotechnology.org/index.php/exhibitions/campath/scaling

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3349081/

]]> 2018-11-20 00:10:51 UTC https://padlet.com/e_bhagwatprasad/iib61svj6mfx/wish/306158361 e_bhagwatprasad https://padlet.com/e_bhagwatprasad/iib61svj6mfx/wish/307574290 Regulatory approval was granted by the FDA  and the European Medicines Agency⁴
Clincal trials have been performed in order to find out the lowest possible effective dose needed for patients ]]> 2018-11-25 22:20:04 UTC https://padlet.com/e_bhagwatprasad/iib61svj6mfx/wish/307574290 e_bhagwatprasad https://padlet.com/e_bhagwatprasad/iib61svj6mfx/wish/307574973 Monoclonal antibodies need to be produced, typically using mice, and purified using column chromatography. Following this they are washed with the target molecule, separated into vials and distributed⁴.]]> 2018-11-25 22:25:40 UTC https://padlet.com/e_bhagwatprasad/iib61svj6mfx/wish/307574973 e_bhagwatprasad https://padlet.com/e_bhagwatprasad/iib61svj6mfx/wish/307577228 Primary consumers for this product include hospitals and clinics that treat patients with chronic lymphocytic leukemia. ]]> 2018-11-25 22:41:54 UTC https://padlet.com/e_bhagwatprasad/iib61svj6mfx/wish/307577228